Results 11 to 20 of about 579,790 (305)

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation

Frontiers in Bioengineering and Biotechnology, 2021
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen, Sarah J. B. Snelling, Andrew J. Carr, Stephanie G. Dakin   +3 more
doaj   +1 more source

Relationship between interleukin 17 & 6 in patients with varicocele compare with a control group [PDF]

Journal of Medical and Life Science, 2019
The spermatogenesis process is very complex and involves many processes that lead to giving normal sperm, these sperms are very important for Fertility in the male.
Hayder AL-Msaid, Waleed H., Hydar Khalfa
doaj   +1 more source

The comparison of the salivary concentration of interleukin-17 and interleukin-18 in patients with chronic periodontitis and healthy individuals

Dental Research Journal, 2020
Background: Regarding the prevalence and importance of periodontal disease and the potential of salivary biomarkers for the early diagnosis of these diseases, this study was conducted to compare salivary concentrations of Interleukin-17 (IL-17) and ...
Surena Vahabi, Zahra Yadegari, Samaneh Pournaghi   +2 more
doaj   +1 more source

Dramatic secukinumab-mediated improvements in refractory leprosy-related neuritis via the modulation of T helper 1 (Th1) and T helper 17 (Th17) immune pathways

Revista da Sociedade Brasileira de Medicina Tropical, 2021
A 39-year-old woman was diagnosed with relapsed multibacillary leprosy and refractory neuritis. Here, we describe an evident loss of therapeutic effectiveness after the third pulse of corticosteroids, which may be attributed to tachyphylaxis and the ...
Patrícia Shu Kurizky, Jorgeth de Oliveira Carneiro da Motta, Natanael Victor Furtunato Bezerra, Marcia Carolline dos Santos Sousa, Danilo Corazza, Taiana Karla dos Santos Borges, Ciro Martins Gomes   +6 more
doaj   +1 more source

SELEX-discovered aptamer that inhibits cellular interleukin-17/interleukin-17 receptor interaction and antagonizes interleukin-17 signaling

Bioscience, Biotechnology, and Biochemistry, 2023
ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi, Tong Wang, Yukio Takamori, Takehiro Ando, Takumi Yokoyama, Daisuke Fuji, Zhehao Xu, Santhana Vedi, Mizuki Yamamoto, Keita Tsukamoto, Takashi Kawakami   +10 more
openaire   +2 more sources

Current concepts in the pathogenesis of spondyloarthritis

Indian Journal of Rheumatology, 2020
Pathogenesis of spondyloarthritis (SpA) is multifactorial and still not understood entirely. The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us ...
Nibha Jain, Arumugam Moorthy
doaj   +1 more source

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Harnett, M.M., Pineda, Miguel, McGrath, Mairi, Al-Riyami, Lamyaa, Pineda, M.A., Harnett, W., Pauline C. Smith, Lamyaa Al-Riyami, Harnett, Margaret, Miguel A. Pineda, Smith, P.C., Smith, Pauline, J. Alastair Gracie, Harnett, William, McGrath, M.A., Rzepecka, J., Gracie, Alastair, Rzepecka, Justyna, Margaret M. Harnett, Al-Riyami, L., Gracie, J.A., Justyna Rzepecka, Mairi A. McGrath, William Harnett   +23 more
core   +1 more source

Interleukin-6 levels in the control and AAA groups.

, 2023
There was no significant difference in plasma levels of IL-6 between groups (P = .17). AAA, abdominal aortic aneurysm; IL-6, interleukin-6.
Lenka Maliskova (8781746), Robert L. Raffai (12633072), Shant M. Vartanian (14614693), Adam Z. Oskowitz (14614696), Andrea J. Barczak (782932), Laura Bouchareychas (3493793), Michael S. Conte (12160976), Joshua D. Rudolph (14614690), Phat Duong (5718677), Jose L. Lopez (14614678), Tuan Anh Phu (14614684), Christina R. Kuhrau (14614687), Pei-Yu Lin (3370841), Walter L. Eckalbar (9243670), Joel L. Ramirez (14614681)   +14 more
core   +1 more source

The interleukin-23/interleukin-17 axis in spondyloarthritis [PDF]

Current Opinion in Rheumatology, 2008
To inform readers of recent advances in our understanding of the development and function of Th17 T cells and emerging data suggesting that the interleukin-23/interleukin-17 axis may be involved in the pathogenesis of spondyloarthritis.The discovery of CD4+ Th17 T cells and the interleukin-23/interleukin-17 axis has challenged existing paradigms and ...
Gerlinde, Layh-Schmitt, Robert A, Colbert   +1 more
openaire   +2 more sources

ES-62 protects against collagen-induced arthritis by resetting interleukin-22 towards resolution of inflammation in the joints [PDF]

, 2014
Objective. The parasitic worm–derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17 associated cytokine
Al-Riyami, Lamyaa, Pineda, Miguel A, Rodgers, David T, Harnett, Margaret M., Harnett, Margaret, Miguel A. Pineda, Lamyaa Al‐Riyami, Harnett, William, Rodgers, David T., David T. Rodgers, Margaret M. Harnett, Pineda, Miguel A., William Harnett   +12 more
core   +1 more source