Results 41 to 50 of about 3,701,935 (349)

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

Journal of Experimental Medicine, 2020
IL17 cross-talk with pancreatic cancer cells orchestrates neutrophil recruitment and activation of Padi4-dependent NETosis, resulting in immune spatial remodeling and immunosuppression reversal.
Yu Zhang, Vidhi Chandra, E. Riquelme Sanchez, Prasanta Dutta, P. Quesada, Amanda I Rakoski, Michelle Zoltan, Nivedita Arora, Seyda Baydogan, W. Horne, J. Burks, Hanwen Xu, Perwez Hussain, Huamin Wang, Sonal Gupta, A. Maitra, Jennifer M. Bailey, S. Moghaddam, Sulagna Banerjee, I. Sahin, P. Bhattacharya, F. McAllister   +21 more
semanticscholar   +1 more source

Interleukin – 17 and interleukin-10 as inflammatory and prevention biomarkers in periimplant diseases

International Journal of Preventive Medicine, 2019
Background: Periimplant diseases are inflammatory diseases. Thus, the level of preinflammatory cytokines which has important role in the inflammation processes can consider as biomchemical markers for early diagnosis and prevention of periimplant ...
Shirin Zahra Farhad, Faeze Rezazadeh, Majid Mohammadi   +2 more
doaj   +1 more source

Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans

Science Translational Medicine, 2020
Interleukin 17 and senescent cells regulate fibrosis in the foreign body response to synthetic material implants. Elucidating the foreign body response Synthetic materials are the building blocks for medical devices and implants but can induce a foreign ...
Liam Chung, David R Maestas, Andriana Lebid, Ashlie Mageau, G. Rosson, Xinqun Wu, Matthew T. Wolf, A. Tam, Isabel Vanderzee, Xiaokun Wang, James I. Andorko, Hong Zhang, Radhika Narain, Kaitlyn Sadtler, H. Fan, Daniela Čiháková, C. L. Le Saux, F. Housseau, D. Pardoll, J. Elisseeff   +19 more
semanticscholar   +1 more source

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +2 more sources

Interleukin 17 in vascular inflammation [PDF]

Cytokine & Growth Factor Reviews, 2010
Interleukin (IL)-17 (also known as IL-17A) is produced by activated T cells. It is a marker cytokine of the T(H₁₇) lineage. IL-17 production is induced in infections, autoimmune diseases and other inflammatory events. IL-17 is involved in host defense, but also inflammatory tissue destruction.
Sibylle, von Vietinghoff, Klaus, Ley
openaire   +2 more sources

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan   +23 more
core   +1 more source

Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study

BMC Rheumatology, 2020
Background Osteoarthritis (OA) is a progressive, chronic disease characterized by articular cartilage destruction. The pro-inflammatory cytokine IL-17 levels have been reported elevated in serum and synovial fluid of OA patients and correlated with ...
Dovile Sinkeviciute, Anders Aspberg, Yi He, Anne-Christine Bay-Jensen, Patrik Önnerfjord   +4 more
doaj   +1 more source

Interleukin-35 Is Involved in Angiogenesis/Bone Remodeling Coupling Through T Helper 17/Interleukin-17 Axis

Frontiers in Endocrinology, 2021
ObjectiveOsteoporosis is a common metabolic bone disease mainly involving bone remodeling and blood vessels. The current study aimed to explore the suppressive role of interleukin (IL)-35 in nuclear factor kappa-B ligand receptor activator (RANKL) and ...
Hui Zhang, Yuxuan Li, Lin Yuan, Lutian Yao, Jie Yang, Liping Xia, Hui Shen, Jing Lu   +7 more
doaj   +1 more source

The effect of hymenoptera venom immunotherapy on neutrophils, interleukin 8 (IL-8) and interleukin 17 (IL-17)

International Journal of Occupational Medicine and Environmental Health, 2020
Objectives Venom immunotherapy (VIT) is an effective treatment method and is addressed to patients with a history of an anaphylactic reaction to Hymenoptera stings. However, the immunological mechanisms of protection have not been explained yet.
Krzysztof Pałgan, Magdalena Żbikowska-Gotz, Robert Zacniewski, Zbigniew Bartuzi   +3 more
doaj   +1 more source

New Findings on Autoimmune Etiology of Idiopathic Granulomatous Mastitis: Serum IL-17, IL-22 and IL-23 Levels of Patients

Journal of Investigative Surgery, 2021
Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam, Kerim Bora Yilmaz, Mutlu Sahin, Hamdullah Yanik, Melih Akinci, Ibrahim Yilmaz, Sener Balas, Cem Azili, Mehmet Ali Gulcelik   +8 more
doaj   +1 more source