Results 51 to 60 of about 3,701,935 (349)

Airway neutrophils and interleukin-17 [PDF]

European Respiratory Journal, 2000
It is well known that exacerbations of obstructive airways disease such as asthma and chronic obstructive pulmonary disease are associated with an increased number of neutrophils in the airways. However, the mechanisms behind this phenomenon are poorly understood.
A, Lindén, H, Hoshino, M, Laan
openaire   +2 more sources

Paradoxical gastrointestinal effects of interleukin-17 blockers

Annals of the Rheumatic Diseases, 2020
Secukinumab, ixekizumab and brodalumab are monoclonal antibody therapies that inhibit interleukin (IL)-17 activity and are widely used for the treatment of psoriasis, psoriatic arthritis and ankylosing spondylitis.
M. Fauny, D. Moulin, F. D'amico, P. Netter, N. Petitpain, D. Arnone, J. Jouzeau, D. Loeuille, L. Peyrin-Biroulet   +8 more
semanticscholar   +1 more source

Influence of interleukin 17 A and 17 F polymorphisms in keratoconus [PDF]

, 2021
Background: Until a few years ago, keratoconus was defined as a noninflammatory degenerative disease. However, recent studies have shown that the altered balance between inflammatory cytokines, proteases, and protease inhibitors, as well as free radicals
Ayo, Christiane Maria, de Mattos, Luiz Carlos, Gomes, Isabela Bronchtein, Kumano, Laurie Sayuri, de Faria Junior, Geraldo Magela, Lopes, Alessandro Garcia [UNESP], Brandão, Cinara Cássia, de Almeida, Gildásio Castello, Castiglioni, Lilian [UNESP]   +8 more
core   +1 more source

Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]

, 2011
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M, Pathan, Ansar A, Sander Clare R., Hill, Adrian, Helen A. Fletcher, Fletcher, Helen A, Natalie E R Beveridge, Hill, AVS, Minassian Angela M., Angela M Minassian, Fletcher, HA, Kristin L. Griffiths, Pathan Ansar A., Kristin L Griffiths, Hill, Adrian VS, Griffiths Kristin L., Sander, CR, Hill Adrian V. S., McShane Helen, Beveridge Natalie E. R., Pathan, AA, Minassian, AM, Clare R. Sander, Ansar A. Pathan, Hill, AV, Griffiths, KL, Beveridge, NER, Clare R Sander, Helen McShane, Ansar A Pathan, Beveridge, NE, Natalie E. R. Beveridge, Griffiths , Kristin Lisa, Griffiths, Kristin L, Sander, Clare R, Adrian V S Hill, Adrian V. S. Hill, Helen A Fletcher, Fletcher Helen A., Beveridge, Natalie ER, McShane, H, Fletcher, Helen, Angela M. Minassian, McShane, Helen   +43 more
core   +1 more source

Serum interleukin-17 (IL-17) in chronic periodontitis patients

Padjadjaran Journal of Dentistry, 2017
Introduction: Explorations into the periodontal medicine relationship have discovered interleukin-17 (IL-17) cytokine as one of the pro-inflammatory mediators that play a crucial role in the initiation and progression of the chronic periodontal disease ...
Erry Mochamad Arief, Marina binti Mubin, Siti Lailatul Akmar Zainuddin, Nurul Asma Abdullah, Basaruddin Ahmad   +4 more
doaj   +1 more source

Interleukin-17: A Revisited Study [PDF]

International Journal of Immunopathology and Pharmacology, 2004
Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses.
HUANG SH, FRYDAS S, CONTI, Pio, KEMPURAJ D, BARBACANE, Renato Carmine, GRILLI, Alfredo, BOUCHER W, LETOURNEAU R, PAPADOPOULOU N, DONELAN J, MADHAPPAN B, THEOHARIDES TC, DE LUTIIS, Maria Anna, RICCIONI, Graziano, SABATINO, Giuseppe   +14 more
openaire   +3 more sources

Is interleukin-17 implicated in early knee osteoarthritis pathogenesis as in rheumatoid arthritis?

Egyptian Rheumatology and Rehabilitation, 2022
Background Interleukin-17 (IL-17) is a cytokine that promotes activation of multiple catabolic pathways resulting in cartilage and tissue damage. It has features making it increasingly attractive as a biological marker, especially in rheumatoid arthritis
Hoda M. Abdel-Naby, Sarah S. El-Tawab, Mohamed M. Rizk, Nesrin A. Aboeladl   +3 more
doaj   +1 more source

The Treatment with Interleukin 17 Inhibitors and Immune-Mediated Inflammatory Diseases

Current Issues in Molecular Biology, 2022
IL-17 inhibitors (IL-17i) are medicines used to treat dermatological and rheumatic diseases They belong to a class of medicines called biological disease-modifying anti-rheumatic drugs (bDMARDs).
Laura Țiburcă, Marius Bembea, Dana Carmen Zaha, Alexandru Daniel Jurca, Cosmin Mihai Vesa, Ioana Adela Rațiu, Claudia Maria Jurca   +6 more
doaj   +1 more source

Biology of Interleukin-17 and Its Pathophysiological Significance in Sepsis

Frontiers in Immunology, 2020
The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer.
Yun Ge, Man Huang, Yong-Ming Yao
semanticscholar   +1 more source

Current perspective on the role of the interleukin-23/interleukin-17 axis in inflammation and disease (chronic arthritis and psoriasis) [PDF]

, 2015
TH17 is a lymphocyte subset, which is characterized by its polarization to secrete interleukin (IL)-17. IL-23 is the pivotal mediator responsible for TH17 differentiation and the IL-23/IL-17 axis has been strongly implicated in the pathogenesis of ...
PIGA, MATTEO, Floris A, MATHIEU, ALESSANDRO, CAULI, ALBERTO, Piga M, Mathieu A, FLORIS, ALBERTO, Cauli A   +7 more
core   +1 more source