Results 1 to 10 of about 6,985,286 (295)

Immunobiology of IL-17A in human colorectal cancer [PDF]

, 2015
During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
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The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Harnett, M.M., Pineda, Miguel, McGrath, Mairi, Al-Riyami, Lamyaa, Pineda, M.A., Harnett, W., Pauline C. Smith, Lamyaa Al-Riyami, Harnett, Margaret, Miguel A. Pineda, Smith, P.C., Smith, Pauline, J. Alastair Gracie, Harnett, William, McGrath, M.A., Rzepecka, J., Gracie, Alastair, Rzepecka, Justyna, Margaret M. Harnett, Al-Riyami, L., Gracie, J.A., Justyna Rzepecka, Mairi A. McGrath, William Harnett   +23 more
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IL-17 levels measured in CSF (preoperatively).

, 2021
IL-17 levels measured in CSF (preoperatively).
Regina Carlson (388166), Annika Kämpe (11507012), Karl Rohn (555695), Andrea Tipold (192569), Anna Knebel (6757913)   +4 more
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B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response [PDF]

, 2013
We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by
Porcelli, SA, Wang, Yanhua, Steven A. Porcelli, William R Jacobs, Flynn, Joanne L, Chen, Y, John Chan, Kozakiewicz, Lee, Qinglin Ou, Lee Kozakiewicz, Chan, John, Xu, J, Ou, Qinglin, Yong Chen (109188), John Chan (47914), Jacobs, WR, Flynn, JL, Ou, Q, Jacobs, William R, William R. Jacobs, Dunussi-Joannopoulos, K, Dunussi-Joannopoulos, Kyri, Steven A. Porcelli (47915), Chen, Yong, Joanne L Flynn, Xu, Jiayong, Kozakiewicz, L, Jiayong Xu (432778), Wang, Y, Joanne L. Flynn (5655565), William R. Jacobs Jr (199645), Chan, J, Lee Kozakiewicz (432777), Qinglin Ou (432779), Joanne L. Flynn, Yanhua Wang, Porcelli, Steven A, Yanhua Wang (127897), Jiayong Xu, Steven A Porcelli, Yong Chen, Kyri Dunussi-Joannopoulos, Kyri Dunussi-Joannopoulos (344714)   +42 more
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IL-17 levels measured in serum (preoperatively).

, 2021
IL-17 levels measured in serum (preoperatively).
Regina Carlson (388166), Annika Kämpe (11507012), Karl Rohn (555695), Andrea Tipold (192569), Anna Knebel (6757913)   +4 more
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Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Pfeilschifter, Josef, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Koehl, Ulricke, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +40 more
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Elucidation of breast cancer lung metastasis by IL-17 through the modulation of stromal cells and the development of treatment model [PDF]

, 2020
炎症性サイトカインであるIL-17は炎症や自己免疫疾患、癌の増殖において重要な働きを有するが、転移促進の機序は明らかでない。我々はマウス乳がん細胞株4T1を野生型(WT)およびIL-17A欠損(KO)マウス乳腺内に担癌すると、腫瘍径は両群で差はないが、IL-17KOマウスでは肺転移が著明に抑制される系を確立した。本研究ではこのモデルを用いてIL-17Aが腫瘍形成早期の時点で血管新生の増強、単球からM2型マクロファージへの分化促進、主要微小環境の免疫抑制状態に寄与していることを明らかにした ...
サイトウ, カナコ, Kato, Takuma, カトウ, タクマ, 齋藤, 佳菜子, Saito, Kanako, 加藤, 琢磨   +5 more
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IL-17 and IL-1β stimulate ERK and STAT3 in SFs.

, 2021
Flow cytometric analysis of (A) ERK and (B) STAT3 activation, determining the relative expression of dually phosphorylated versus total ERK or phosphorylated STAT3 versus total STAT3 expression, following incubation of Naïve-SFs in medium alone or ...
Felicity E. Lumb (8566887), William Harnett (848414), Margaret M. Harnett (1304640), Sarah McGrath (11663424), Rinako Nakagawa (5830145), Miguel A. Pineda (8566893), Kun Yang (19445), Marlene Corbet (11663421), Anuradha Tarafdar (489798), Colin J. Suckling (1268478)   +9 more
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IL-17はRAW264.7細胞のRANKL誘導性破骨細胞分化をダウンレギュレートする [PDF]

大阪歯科大学Osaka Dental University博士（歯学）In orthodontic treatment, tooth movement occurs based on bone remodeling in response to orthodontic forces. Interleukin-17A (IL-17) is a proinflammatory cytokine that is primarily secreted by Th17 cells.
Fukawa, Akito, フカワ, アキト, 布川, 朗人   +2 more
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IL-23/IL-17 axis and disease activity in systemic lupus erythematosus patients [PDF]

, 2020
Introduction: The latest paradigm proposes that imbalance of Treg and Th17 cells play a significant role in Systemic Lupus Erythematosus (SLE) pathogenesis. The influence of IL-23 and IL-17 on the pathogenesis of SLE remains controversial.
Tri Yanti, Yuliasih, Lita Diah Rahmawati
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