Results 1 to 10 of about 2,037,860 (143)

Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population

open access: yesMutiara Medika, 2021
Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
doaj   +1 more source

Parapoxvirus Interleukin-10 Homologues Vary in Their Receptor Binding, Anti-Inflammatory, and Stimulatory Activities

open access: yesPathogens, 2022
Homologues of interleukin (IL)-10, a pleiotropic immunomodulatory cytokine, have been identified in the Parapoxvirus genus. The first identified, Orf virus (ORFV) IL-10, greatly enhanced infection of its host, exhibiting immune modulatory effects ...
Amreen Naqash   +3 more
doaj   +1 more source

IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review

open access: yesDiyala Journal of Medicine, 2023
Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings.
Maha Abdulsalam Mohammed ,   +1 more
doaj   +1 more source

Artificial Intelligence Algorithms for Treatment of Diabetes

open access: yesAlgorithms, 2022
Artificial intelligence (AI) algorithms can provide actionable insights for clinical decision-making and managing chronic diseases. The treatment and management of complex chronic diseases, such as diabetes, stands to benefit from novel AI algorithms ...
Mudassir M. Rashid   +5 more
doaj   +1 more source

Modulation of human immune responses by bovine interleukin-10 [PDF]

open access: yes, 2011
Cytokines can be functionally active across species barriers. Bovine IL-10 has an amino acid sequence identity with human IL-10 of 76.8%. Therefore, the aim of this study was to evaluate whether bovine IL-10 has immunomodulatory activities on human ...
Hartog, C.G., den   +7 more
core   +11 more sources

Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]

open access: yes, 2018
Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena   +3 more
core   +6 more sources

Toll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection

open access: yesVirulence, 2020
Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection.
Jaehun Park   +6 more
doaj   +1 more source

Gestational Age-Dependent Regulation of Transthyretin in Mice during Pregnancy

open access: yesBiology, 2023
Our prior studies have shown that protein misfolding and aggregation in the placenta are linked to the development of preeclampsia, a severe pregnancy complication.
Shibin Cheng   +3 more
doaj   +1 more source

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

open access: yes, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea   +6 more
core   +1 more source

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

open access: yes, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core   +5 more sources

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