Results 11 to 20 of about 77,599,971 (244)

Comparison of Serum Interleukin 10 Levels between Leprosy and Non-Leprosy Population

open access: yesMutiara Medika, 2021
Leprosy is a chronic granulomatous infectious disease that attacks the peripheral nerves, skin, and other organs. The cytokine IL-10 can deactivate macrophages, inhibit IL-12 production, which also inhibits IFN-ϒ production. IL-10 directly inhibits CD4+T
Adika Kodrati, Eddy Mart Salim, Zen Hafy
doaj   +1 more source

Parapoxvirus Interleukin-10 Homologues Vary in Their Receptor Binding, Anti-Inflammatory, and Stimulatory Activities

open access: yesPathogens, 2022
Homologues of interleukin (IL)-10, a pleiotropic immunomodulatory cytokine, have been identified in the Parapoxvirus genus. The first identified, Orf virus (ORFV) IL-10, greatly enhanced infection of its host, exhibiting immune modulatory effects ...
Amreen Naqash   +3 more
doaj   +1 more source

IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review

open access: yesDiyala Journal of Medicine, 2023
Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings.
Maha Abdulsalam Mohammed ,   +1 more
doaj   +1 more source

Artificial Intelligence Algorithms for Treatment of Diabetes

open access: yesAlgorithms, 2022
Artificial intelligence (AI) algorithms can provide actionable insights for clinical decision-making and managing chronic diseases. The treatment and management of complex chronic diseases, such as diabetes, stands to benefit from novel AI algorithms ...
Mudassir M. Rashid   +5 more
doaj   +1 more source

Cytokine gene polymorphisms in lymphoma: Thesis Abstract [PDF]

open access: yesEgyptian Journal of Cancer and Biomedical Research, 2021
Thesis Abstract Several cytokines are known to be involved in the pathogenesis of non-Hodgkin Lymphomas (NHL). Given the importance of understanding the genetic predisposition involved in the pathogenesis of NHL, this work was designed to study the ...
naser Abd El Bary   +3 more
doaj   +1 more source

Toll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection

open access: yesVirulence, 2020
Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection.
Jaehun Park   +6 more
doaj   +1 more source

Gestational Age-Dependent Regulation of Transthyretin in Mice during Pregnancy

open access: yesBiology, 2023
Our prior studies have shown that protein misfolding and aggregation in the placenta are linked to the development of preeclampsia, a severe pregnancy complication.
Shibin Cheng   +3 more
doaj   +1 more source

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

open access: yes, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core   +1 more source

BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]

open access: yes, 2011
Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington   +29 more
core   +3 more sources

Effect of IL-10-producing B cells in peripheral blood and tumor tissue on gastric cancer

open access: yesCell Communication and Signaling, 2023
Background Interleukin (IL)-10-producing B (B10) cells are generated in response to signals from the tumor microenvironment and promote tumor growth by interacting with B10 cells.
Yoon Ju Jung   +9 more
doaj   +1 more source

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