Results 1 to 10 of about 397,057 (96)
PLoS ONE, 2023 Interleukin-1β (IL-1β) is one of the most potent pro-inflammatory cytokines implicated in a wide range of autoinflammatory, autoimmune, infectious, and degenerative diseases.
Hae-Ri Lee +8 more
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Serum IL–1β, IL–2, IL–6, and IL–8 levels in schizophrenia subtypes
Psychiatry and Clinical Psychopharmacology, 2021 Objective: The cytokines are considered to be an important topic in immunological studies of schizophrenia. In this clinical study IL-1β, IL-2, IL-6, and IL-8 levels were compared among schizophrenia subtypes and a control group.
Murat Kuloglu +4 more
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Tpl2 contributes to IL-1β-induced IL-8 expression via ERK1/2 activation in canine dermal fibroblasts
PLoS ONE, 2021 In autoimmune diseases, fibroblasts produce and secrete various cytokines and act as sentinel immune cells during inflammatory states. However, the contribution of sentinel immune cells (i.e.
Atsuto Naruke +9 more
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IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation. [PDF]
PLoS ONE, 2012 Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1β-driven neuroinflammation in the pathogenesis of diabetic retinopathy.
Yang Liu +2 more
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Molecules, 2023 IL-1β mediates inflammation and regulates immune responses, cell proliferation, and differentiation. Dysregulation of IL-1β is linked to inflammatory and autoimmune diseases.
Ting-ting Liu +9 more
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Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome
Veterinary Research, 2020 Newcastle disease virus (NDV) infection causes severe inflammation and is a highly contagious disease in poultry. Virulent NDV strains (GM) induce large quantities of interleukin-1β (IL-1β), which is the central mediator of the inflammatory reaction ...
Pei Gao +14 more
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Медицинская иммунология, 2014 . Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region.
A. L. Burmistrova +5 more
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IL-1β turnover by the UBE2L3 ubiquitin conjugating enzyme and HECT E3 ligases limits inflammation
Nature Communications, 2023 The cytokine interleukin-1β (IL-1β) has pivotal roles in antimicrobial immunity, but also incites inflammatory disease. Bioactive IL-1β is released following proteolytic maturation of the pro-IL-1β precursor by caspase-1.
Vishwas Mishra +13 more
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Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms
Frontiers in Immunology, 2018 Betaine is a critical nutrient for mammal health, and has been found to alleviate inflammation by lowering interleukin (IL)-1β secretion; however, the underlying mechanisms by which betaine inhibits IL-1β secretion remain to be uncovered. In this review,
Yaoyao Xia +11 more
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Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils
Frontiers in Immunology, 2018 Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula +13 more
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