Results 1 to 10 of about 6,778,674 (329)

Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction.

PLoS ONE, 2023
Interleukin-1β (IL-1β) is one of the most potent pro-inflammatory cytokines implicated in a wide range of autoinflammatory, autoimmune, infectious, and degenerative diseases.
Hae-Ri Lee, Young-Jin Jeong, Joong-Woon Lee, JooYeon Jhun, Hyun Sik Na, Keun-Hyung Cho, Seok Jung Kim, Mi-La Cho, Tae-Hwe Heo   +8 more
doaj   +3 more sources

Serum IL–1β, IL–2, IL–6, and IL–8 levels in schizophrenia subtypes

Psychiatry and Clinical Psychopharmacology, 2021
Objective: The cytokines are considered to be an important topic in immunological studies of schizophrenia. In this clinical study IL-1β, IL-2, IL-6, and IL-8 levels were compared among schizophrenia subtypes and a control group.
Murat Kuloglu, Yılmaz Bayik, Ahmet Unal, Omer Gecici, Bilal Ustundag   +4 more
doaj   +1 more source

Relationship between IL-6, IL-1β, and vitamin D on frailty status in elderly women

Bali Medical Journal, 2021
Background: The aging process is associated with an increase in proinflammatory markers' serum levels, indicating that a chronic inflammatory process is correlated with an increase in disability, mortality, and frailty. Pro-inflammatory cytokines that increase with the incidence of frailty syndrome are IL-6, IL-1β and TNF-α.
Dwi Ngestiningsih, Jessa Kris Dayanti, Lusiana Batubara   +2 more
openaire   +1 more source

IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance.

Molecules and Cells, 2023
Interleukin-1β (IL-1β) is a key protein in inflammation and contributes to tumor progression. However, the role of IL-1β in cancer is ambiguous or even contradictory.
Yi Han, Yan-Yu Zhang, Yi-Qian Pan, Xiao-Jun Zheng, Kun Liao, Hai-Yu Mo, Hui Sheng, Qi-Nian Wu, Ze-Xian Liu, Z. Zeng, Wei Yang, Shu-Qiang Yuan, Peng Huang, H. Ju, Ruifeng Xu   +14 more
semanticscholar   +1 more source

Tpl2 contributes to IL-1β-induced IL-8 expression via ERK1/2 activation in canine dermal fibroblasts.

PLoS ONE, 2021
In autoimmune diseases, fibroblasts produce and secrete various cytokines and act as sentinel immune cells during inflammatory states. However, the contribution of sentinel immune cells (i.e.
Atsuto Naruke, Rei Nakano, Junichi Nunomura, Yoko Suwabe, Masumi Nakano, Shinichi Namba, Taku Kitanaka, Nanako Kitanaka, Hiroshi Sugiya, Tomohiro Nakayama   +9 more
doaj   +2 more sources

IL-1β and the Intestinal Epithelial Tight Junction Barrier

Frontiers in Immunology, 2021
The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of contents from the intestinal lumen into the intestinal tissue and systemic circulation.
L. Kaminsky, Rana Al-Sadi, T. Ma
semanticscholar   +1 more source

Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A

Cell Reports, 2022
SUMMARY Peripheral artery disease (PAD) leads to considerable morbidity, yet strategies for therapeutic angiogenesis fall short of being impactful. Inflammatory macrophage subsets play an important role in orchestrating post-developmental angiogenesis ...
C. Mantsounga, Cadence Lee, Jade Neverson, Shipra Sharma, A. Healy, Joshua Berus, Crystal Parry, Nicolle M. Ceneri, F. López-Giráldez, Hyung J. Chun, Q. Lu, F. Sellke, G. Choudhary, A. Morrison   +13 more
semanticscholar   +1 more source

The expression of TNF-α, IL-1β, and IL-10 in the diabetes mellitus condition induced by the combination of spirulina and chitosan

Bali Medical Journal, 2020
Background: Rapid wound healing is needed after tooth extraction treatment so that prosthodontics treatment can be done immediately. However, systemic diseases, such as diabetes mellitus, can inhibit the wound healing process. The state of hyperglycemia in people with diabetes mellitus can interfere with the function of macrophages and neutrophils ...
Nike Hendrijantini, -, Ratri Maya Sitalaksmi, -, Muhammad Dimas Aditya Ari, -, Tiffany Josephine Hidayat, -, Prisca Agustina Nurcahyani Putri, -, Daniel Sukandar, -   +5 more
openaire   +1 more source

Acute systemic inflammation exacerbates neuroinflammation in Alzheimer’s Disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction

Alzheimer's & Dementia, 2021
Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require elucidation.
A. López-Rodríguez, E. Hennessy, C. Murray, A. Nazmi, Hugh J Delaney, Dáire Healy, Steven G. Fagan, Michael Rooney, E. Stewart, Anouchka Lewis, Niamh de Barra, Philip L. Scarry, Louise Riggs-Miller, D. Boche, M. Cunningham, C. Cunningham   +15 more
semanticscholar   +1 more source

IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation. [PDF]

PLoS ONE, 2012
Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1β-driven neuroinflammation in the pathogenesis of diabetic retinopathy.
Yang Liu, Montserrat Biarnés Costa, Chiara Gerhardinger   +2 more
doaj   +1 more source