Results 11 to 20 of about 3,308,702 (244)
The emerging role of Interleukin 1β (IL-1β) in cancer cachexia [PDF]
, 2021 Treatment of cancer cachexia remains an unmet need. The host-tumour interface and the resulting sequestration of the pro-inflammatory cytokine Il-1β is critical in cachexia development.
Laird, Barry J +12 more
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Platelet-Rich Fibrin Reduces IL-1β Release from Macrophages Undergoing Pyroptosis [PDF]
, 2022 Background: Pyroptosis is a catabolic process relevant to periodontal disorders for which interleukin-1β (IL-1β) inflammation is central to the pathophysiology of the disease.
Gruber, Reinhard +7 more
core +1 more source
IL-1β promotes immunoregulatory responses in human blood basophils.
, 2021 Human basophils are essential effector cells of chronic allergic inflammation. IL-1 family cytokines such as interleukin (IL)-33 and IL-1β are elevated in serum and bronchoalveolar lavage fluid of allergic asthmatics.
Fux, Michaela +9 more
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IL-1β-induced activation of ERK1/2.
, 2021 (a, b) Time-dependent changes of ERK1/2 phosphorylation. Western blotting for the levels of phosphorylated ERK1/2 (p-ERK1/2) and total ERK1/2 (t-ERK1/2) in dermal fibroblasts treated with IL-1β (100 pM) (a) and relative levels of [p-ERK1/2]/[t-ERK1/2] in
Taku Kitanaka (3350276) +9 more
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IL-1β-induced IL-8 release and IL-8 mRNA expression in canine dermal fibroblasts.
, 2021 Time-dependent increase in IL-8 protein release (a) and IL-8 mRNA expression levels (b) in cells treated with (closed circle) or without (open circle) canine recombinant IL-1β (100 pM).
Taku Kitanaka (3350276) +9 more
core +1 more source
IL-1β mediates miR-155 upregulation by colitis in cardiomyocytes.
, 2021 (A) IL-1β upregulated miR-155 in H9c2 cells. Cells were treated with H2O2, TNF-α, IL-1β or LPS for 24 hours. miR-155 levels were quantitated by TaqMan-based RT-qPCR with 18S ribosomal RNA as endogenous control.
Yanbo Tang (11457519) +9 more
core +1 more source
IL-1β affected the expression of PAPP-A mRNA.
, 2023 The increased IL-1β mRNA expression level was observed in model group, which was significantly reduced in IL-1β knockdown group (A). The PAPP-A mRNA expression level was observed in model group, which was significantly downregulated by the IL-1β ...
Rui Min (4039946) +6 more
core +1 more source
Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D/bioreactor model [PDF]
, 2013 IntroductionThe present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs.MethodsNatriuretic peptide (Npr) 2 and 3 expression were compared in ...
Salter, Donald M +31 more
core +1 more source
Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms
Frontiers in Immunology, 2018 Betaine is a critical nutrient for mammal health, and has been found to alleviate inflammation by lowering interleukin (IL)-1β secretion; however, the underlying mechanisms by which betaine inhibits IL-1β secretion remain to be uncovered. In this review,
Yaoyao Xia +11 more
doaj +1 more source
Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils
Frontiers in Immunology, 2018 Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula +13 more
doaj +1 more source