Results 11 to 20 of about 4,734,962 (279)

Release of IL-1β via IL-1β-Converting Enzyme in a Skin Dendritic Cell Line Exposed to 2,4-Dinitrofluorobenzene

Mediators of Inflammation, 2005
We used a mouse fetal skin dendritic cell line (FSDC) to study the effect of the strong allergen 2,4-dinitrofluorobenzene (DNFB) on interleukin (IL)-1β release and IL-1β receptor immunoreactivity.
Teresa J. Matos, Sara P. Jaleco, Margarida Gonçalo, Carlos B. Duarte, M. Celeste Lopes   +4 more
doaj   +2 more sources

Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease.

PLoS Pathogens
Inflammasomes play pivotal roles in inflammation by processing and promoting the secretion of IL-1β. Caspase-1 is involved in the maturation of IL-1β and IL-18, while human caspase-4 specifically processes IL-18.
Xiangyu Huang, Zhenchao Zhao, Cheng Zhu, Lvye Chai, Ya Yan, Ye Yuan, Lei Wu, Minjie Li, Xiaohan Jiang, Haiwei Wang, Zheng Liu, Pingwei Li, Xin Li   +12 more
doaj   +2 more sources

Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus [PDF]

Proceedings of the National Academy of Sciences, 2015
Significance There is a growing understanding that inflammation impairs synaptic plasticity and cognition and that the aged brain has an elevated sensitivity to cognitive impairment by the proinflammatory cytokine interleukin 1β (IL-1β).
Prieto, GA, Snigdha, S, Baglietto-Vargas, D, Smith, ED, Berchtold, NC, Tong, L, Ajami, D, Laferla, FM, Rebek, J, Cotman, CW   +9 more
openaire   +8 more sources

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway [PDF]

PLoS ONE, 2011
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the catabolic actions of cytokines may have therapeutic potential in the treatment of OA.
Montaseri A., Busch F., Mobasheri A., Buhrmann C., Aldinger C., Rad J. S., Shakibaei M.   +6 more
openaire   +9 more sources

Relationship between IL-6, IL-1β, and vitamin D on frailty status in elderly women

Bali Medical Journal, 2021
Background: The aging process is associated with an increase in proinflammatory markers' serum levels, indicating that a chronic inflammatory process is correlated with an increase in disability, mortality, and frailty. Pro-inflammatory cytokines that increase with the incidence of frailty syndrome are IL-6, IL-1β and TNF-α.
Dwi Ngestiningsih, Jessa Kris Dayanti, Lusiana Batubara   +2 more
openaire   +1 more source

The emerging role of Interleukin 1β (IL-1β) in cancer cachexia [PDF]

, 2021
Treatment of cancer cachexia remains an unmet need. The host-tumour interface and the resulting sequestration of the pro-inflammatory cytokine Il-1β is critical in cachexia development.
Laird, Barry J, McMillan, Donald, Gallagher, Iain J, Skipworth, Richard JE, Paval, D Robert, Skipworth, Richard, Skipworth, Richard J E, Laird, Barry J A, McNeish, I., Gallagher, Iain, Paval, Robert, McNeish, Iain, Fallon, Marie T, Richard J. E. Skipworth, Donald McMillan, Barry J. Laird, Iain McNeish, Marie T. Fallon, D. Robert Paval, Iain J. Gallagher   +19 more
core   +1 more source

IL-1β promotes immunoregulatory responses in human blood basophils. [PDF]

, 2021
Human basophils are essential effector cells of chronic allergic inflammation. IL-1 family cytokines such as interleukin (IL)-33 and IL-1β are elevated in serum and bronchoalveolar lavage fluid of allergic asthmatics.
Fux, Michaela, Sofia Bachmann, Joseena Iype, Iype, Joseena, Bachmann, Sofia, Andrea Odermatt, Mazarine Coeudevez, Michaela Fux, Odermatt, Andrea, Coeudevez, Mazarine   +9 more
core   +1 more source

Platelet-Rich Fibrin Reduces IL-1β Release from Macrophages Undergoing Pyroptosis [PDF]

, 2022
Background: Pyroptosis is a catabolic process relevant to periodontal disorders for which interleukin-1β (IL-1β) inflammation is central to the pathophysiology of the disease.
Gruber, Reinhard, Reinhard Gruber, Panahipour, Layla, Sordi, Mariane Beatriz, Zahra Kargarpour, Kargarpour, Zahra, Mariane Beatriz Sordi, Layla Panahipour   +7 more
core   +2 more sources

The expression of TNF-α, IL-1β, and IL-10 in the diabetes mellitus condition induced by the combination of spirulina and chitosan

Bali Medical Journal, 2020
Background: Rapid wound healing is needed after tooth extraction treatment so that prosthodontics treatment can be done immediately. However, systemic diseases, such as diabetes mellitus, can inhibit the wound healing process. The state of hyperglycemia in people with diabetes mellitus can interfere with the function of macrophages and neutrophils ...
Nike Hendrijantini, -, Ratri Maya Sitalaksmi, -, Muhammad Dimas Aditya Ari, -, Tiffany Josephine Hidayat, -, Prisca Agustina Nurcahyani Putri, -, Daniel Sukandar, -   +5 more
openaire   +1 more source

IL-1β-induced activation of ERK1/2.

, 2021
(a, b) Time-dependent changes of ERK1/2 phosphorylation. Western blotting for the levels of phosphorylated ERK1/2 (p-ERK1/2) and total ERK1/2 (t-ERK1/2) in dermal fibroblasts treated with IL-1β (100 pM) (a) and relative levels of [p-ERK1/2]/[t-ERK1/2] in
Taku Kitanaka (3350276), Tomohiro Nakayama (30894), Nanako Kitanaka (3350285), Masumi Nakano (11648962), Atsuto Naruke (11648956), Hiroshi Sugiya (412101), Rei Nakano (820735), Junichi Nunomura (11648959), Yoko Suwabe (9468965), Shinichi Namba (3350288)   +9 more
core   +1 more source