Results 41 to 50 of about 375,559 (237)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Hyperuricemia and Pro Inflammatory Cytokine (IL-1β, IL-6, and TNF-α)

Indonesian Journal of Rheumatology, 2018
Background. Rugerio et al 2006 reported that there were a positive correlation between the level of hyperuricemia and the level of IL-1β, IL-6, and TNF-α pro infl ammatory cytokines value. On the other hand, Choi et al reported a negative correlation between hyperuricemia and the level of pro infl ammatory cytokine in the late phase of hyperuricemia.
Suyanto Hadi, D Sudarsono, Bantar Suntoko   +2 more
openaire   +1 more source

Additional file 1: of HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway

, 2018
Table S1. Primers list used for quantitative real-time PCR analysis of different genes. Figure S1. Confirmation of HSP60 knockdown by vivo morpholino in mice brain. Figure S2. The overexpression of HSP60 was confirmed by Western blot. Figure S3. JEV induces inflammation in N9 murine microglial cells at MOI 2. (DOCX 1066 kb)
Swaroop, Shalini, Mahadevan, Anita, Shankar, Susarla, Adlakha, Yogita, Basu, Anirban   +4 more
openaire   +1 more source

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway [PDF]

PLoS ONE, 2011
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the catabolic actions of cytokines may have therapeutic potential in the treatment of OA.
Montaseri A., Busch F., Mobasheri A., Buhrmann C., Aldinger C., Rad J. S., Shakibaei M.   +6 more
openaire   +6 more sources

The Correlation b etween IL - 1β and IL - 10 Levels in Estimating t he Risk of Febrile Seizures

Journal of Tropical Life Science, 2014
Febrile seizures are the most-common form of seizures in children with fever and evidence from clinical and experimental studies suggests the potential role of immune generated products in their genesis.
Gunawan A, Muid M, Sujuti H, Barlianto W, Subandiyah K   +4 more
doaj  

PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes[S]

Journal of Lipid Research, 2014
This study examined the role of interleukin (IL)-1 receptor-associated kinase (IRAK) and protein kinase C (PKC) in oxidized LDL (Ox-LDL)-induced monocyte IL-1β production.
Rajiv Lochan Tiwari, Vishal Singh, Ankita Singh, Minakshi Rana, Anupam Verma, Nikhil Kothari, Monica Kohli, Jaishri Bogra, Madhu Dikshit, Manoj Kumar Barthwal   +9 more
doaj   +1 more source

Brain Perivascular Macrophages Do Not Mediate Interleukin-1-Induced Sickness Behavior in Rats

Pharmaceuticals, 2021
Sickness behavior, characterized by on overall reduction in behavioral activity, is commonly observed after bacterial infection. Sickness behavior can also be induced by the peripheral administration of Gram-negative bacterial lipopolysaccharide (LPS) or
Léa Chaskiel, Robert Dantzer, Jan Pieter Konsman   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

WITHDRAWN: IFN-γ and IL-1β treated-human placenta-derived mesenchymal stromal cells enhance the generation of IL-10+T cells by upregulating PDLs expressions and ameliorate experimental autoimmune encephalomyelitis

Oncotarget, 2018
// Zhuoya Wang 1, * , Weiwei Wang 1, * , Yun Hou 2 , Aiping Zhang 1 , Guoyan Wang 3 , Junzhu Yi 1 , Qiang Fu 1 and Xiying Luan 1, 4 1 Department of Immunology, Binzhou Medical University, Shandong Province, Yantai 264003, People’s Republic of China 2 Department of Histology and Embryology, Binzhou Medical University, Shandong Province ...
Zhuoya Wang, Zhuoya Wang, Weiwei Wang, Weiwei Wang, Yun Hou, Yun Hou, Aiping Zhang, Aiping Zhang, Guoyan Wang, Guoyan Wang, Junzhu Yi, Junzhu Yi, Qiang Fu, Qiang Fu, Xiying Luan, Xiying Luan   +15 more
openaire   +1 more source

Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease.

PLoS Pathogens
Inflammasomes play pivotal roles in inflammation by processing and promoting the secretion of IL-1β. Caspase-1 is involved in the maturation of IL-1β and IL-18, while human caspase-4 specifically processes IL-18.
Xiangyu Huang, Zhenchao Zhao, Cheng Zhu, Lvye Chai, Ya Yan, Ye Yuan, Lei Wu, Minjie Li, Xiaohan Jiang, Haiwei Wang, Zheng Liu, Pingwei Li, Xin Li   +12 more
doaj   +1 more source