Results 21 to 30 of about 4,734,962 (279)

Pro-IL-1β is expressed at similar levels in ArpC2 Flox and iKO cells.

, 2023
Mouse fibroblasts were treated with DMSO (Flox) or 4-OHT (iKO) for 6d and collected at 9d. Samples were lysed, subjected to SDS-PAGE, and immunoblotted with antibodies to IL-1β, tubulin, actin, and GAPDH. Pro-IL-1β densitometry values are shown.
Shirley Guo (14515841), Elena L. Haarer (14515835), Corey J. Theodore (14515838), Kenneth G. Campellone (7921649), Ryan B. Frier (14515844)   +4 more
core   +1 more source

IL-1β-induced IL-8 release and IL-8 mRNA expression in canine dermal fibroblasts.

, 2021
Time-dependent increase in IL-8 protein release (a) and IL-8 mRNA expression levels (b) in cells treated with (closed circle) or without (open circle) canine recombinant IL-1β (100 pM).
Taku Kitanaka (3350276), Tomohiro Nakayama (30894), Nanako Kitanaka (3350285), Masumi Nakano (11648962), Atsuto Naruke (11648956), Hiroshi Sugiya (412101), Rei Nakano (820735), Junichi Nunomura (11648959), Yoko Suwabe (9468965), Shinichi Namba (3350288)   +9 more
core   +1 more source

Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur

Jurnal Kedokteran Brawijaya, 2017
Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati, Ferri Waluyo Wiwoho Pujojati, Supriyadi Hari Respati, Soetrisno - -   +3 more
openaire   +2 more sources

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

Cell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]

, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core   +1 more source

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

eLife, 2015
Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells.
Min Zhang, Samuel J Kenny, Liang Ge, Ke Xu, Randy Schekman   +4 more
doaj   +1 more source

Immunomodulatory Effect of Nigella sativa Extract through the Improvement of IL-1β Level in Balb-c Mice Infected by Methicillin-resistant Staphylococcus aureus

Jurnal Kedokteran Brawijaya, 2020
Nigella sativa (NS) has been used for many years as an anti-bacterial herbal treatment, such as Methicillin-resistant Staphylococcus aureus, but the mechanism in bacterial elimination is still unknown. IL-1β is a proinflammatory cytokine that helps the immune system eliminate microbes when it enters the body. The purpose of this study was to prove the
Galuh Yulieta Nitihapsari, Octavia Permata S, Miko Ferine   +2 more
openaire   +2 more sources

Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D/bioreactor model [PDF]

, 2013
IntroductionThe present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs.MethodsNatriuretic peptide (Npr) 2 and 3 expression were compared in ...
Salter, Donald M, Salter, Donald M., Ramachandran, Manoj, Adrian J Hobbs, Hobbs, Adrian J., Ramachandran, M, Moyes, AJ, Amie J Moyes, Peake, Nicholas, Bader, Dan L, Bader, DL, Chowdhury, Tina T., Donald M Salter, Pramod Achan, Bader, Dan L., Peake, N, Su, N, Achan, P, Hobbs, AJ, Salter, DM, Nyan Su, Achan, Pramod, Nicholas Peake, Chowdhury, TT, Moyes, Amie J., Dan L Bader, Tina T Chowdhury, Su, Nyan, Chowdhury, Tina T, Hobbs, Adrian J, Moyes, Amie J, Manoj Ramachandran   +31 more
core   +1 more source

Modulation of human polymorphonuclear leukocyte chemotaxis and superoxide anion production byPseudomonas aeruginosaexoproducts, IL-1β and piroxicam [PDF]

FEMS Immunology & Medical Microbiology, 1995
Whereas addition of 200 ng ml-1 exotoxin A (exoA) did not modify PMNL chemotaxis, 20 U ml-1 human recombinant interleukin-1 beta (hrIL-1 beta) primed polymorphonuclear leukocytes (PMNL) for migration towards Pseudomonas aeruginosa peptide chemotactins (PAPCs).
P A, Fontán, C R, Amura, F R, Buzzola, D O, Sordelli   +3 more
openaire   +2 more sources

The In Situ Expression of IL-6 and IL-1? in breast cancer patients

Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
Breast cancer is the second most common cancer in women world. Multiple Cytokines appear to have a dominant role in human breast cancer formation. Estimation of the in situ expression of  IL-6 and IL-1β in breast cancer patients. A sixty patients with breast cancer BC were divided into two clinical subgroups, (30) with malignant breast cancer MBC and (
Amal H. Salman, Mayada N. Iqbal, Wasan A. Bakir   +2 more
openaire   +3 more sources