Results 21 to 30 of about 375,754 (237)

MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION

Медицинская иммунология, 2014
. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region.
A. L. Burmistrova, D. S. Stashkevich, T. A. Susslova, I. V. Devald, A. O. Issakanova, O. N. Dimcheva   +5 more
doaj   +1 more source

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

Cell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur

Jurnal Kedokteran Brawijaya, 2017
Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati, Ferri Waluyo Wiwoho Pujojati, Supriyadi Hari Respati, Soetrisno - -   +3 more
openaire   +2 more sources

Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms

Frontiers in Immunology, 2018
Betaine is a critical nutrient for mammal health, and has been found to alleviate inflammation by lowering interleukin (IL)-1β secretion; however, the underlying mechanisms by which betaine inhibits IL-1β secretion remain to be uncovered. In this review,
Yaoyao Xia, Yaoyao Xia, Yaoyao Xia, Shuai Chen, Shuai Chen, Guoqiang Zhu, Ruilin Huang, Yulong Yin, Yulong Yin, Yulong Yin, Wenkai Ren, Wenkai Ren   +11 more
doaj   +1 more source

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

Frontiers in Immunology, 2018
Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula, Irene A. Keitelman, Florencia Sabbione, Federico Fuentes, Mauricio Guzman, Jeremías Gastón Galletti, Pehuén Pereyra Gerber, Matías Ostrowski, Jorge R. Geffner, Jorge R. Geffner, Carolina C. Jancic, Carolina C. Jancic, Analía S. Trevani, Analía S. Trevani   +13 more
doaj   +1 more source

Immunomodulatory Effect of Nigella sativa Extract through the Improvement of IL-1β Level in Balb-c Mice Infected by Methicillin-resistant Staphylococcus aureus

Jurnal Kedokteran Brawijaya, 2020
Nigella sativa (NS) has been used for many years as an anti-bacterial herbal treatment, such as Methicillin-resistant Staphylococcus aureus, but the mechanism in bacterial elimination is still unknown. IL-1β is a proinflammatory cytokine that helps the immune system eliminate microbes when it enters the body. The purpose of this study was to prove the
Galuh Yulieta Nitihapsari, Octavia Permata S, Miko Ferine   +2 more
openaire   +2 more sources

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

eLife, 2015
Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells.
Min Zhang, Samuel J Kenny, Liang Ge, Ke Xu, Randy Schekman   +4 more
doaj   +1 more source

Interleukin-1β-Induced Promatrilysin Expression is Mediated by NFκB-Regulated Synthesis of Interleukin-6 in the Prostate Carcinoma Cell Line, LNCaP

Neoplasia: An International Journal for Oncology Research, 2001
Previously, our laboratory showed that interleukin-1β (IL-1β) secreted by lipopolysaccharide-activated monocytes induces promatrilysin expression in the prostate carcinoma cell line, LNCaP.
Mimi Suzanne Maliner-Stratton, Russell D. Klein, Thirupandiyur S. Udayakumar, Raymond B. Nagle, George Timothy Bowden   +4 more
doaj   +1 more source

Modulation of human polymorphonuclear leukocyte chemotaxis and superoxide anion production byPseudomonas aeruginosaexoproducts, IL-1β and piroxicam [PDF]

FEMS Immunology & Medical Microbiology, 1995
Whereas addition of 200 ng ml-1 exotoxin A (exoA) did not modify PMNL chemotaxis, 20 U ml-1 human recombinant interleukin-1 beta (hrIL-1 beta) primed polymorphonuclear leukocytes (PMNL) for migration towards Pseudomonas aeruginosa peptide chemotactins (PAPCs).
P A, Fontán, C R, Amura, F R, Buzzola, D O, Sordelli   +3 more
openaire   +2 more sources

The In Situ Expression of IL-6 and IL-1? in breast cancer patients

Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
Breast cancer is the second most common cancer in women world. Multiple Cytokines appear to have a dominant role in human breast cancer formation. Estimation of the in situ expression of  IL-6 and IL-1β in breast cancer patients. A sixty patients with breast cancer BC were divided into two clinical subgroups, (30) with malignant breast cancer MBC and (
Amal H. Salman, Mayada N. Iqbal, Wasan A. Bakir   +2 more
openaire   +3 more sources