Results 21 to 30 of about 375,754 (237)

MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION

open access: yesМедицинская иммунология, 2014
. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region.
A. L. Burmistrova   +5 more
doaj   +1 more source

NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

open access: yesCell Reports, 2020
The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue, Donado et al. (2020) describe an alternative, two-cell model, to
Jelena S. Bezbradica, Sebastian Joyce
doaj   +1 more source

Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur

open access: yesJurnal Kedokteran Brawijaya, 2017
Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati   +3 more
openaire   +2 more sources

Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms

open access: yesFrontiers in Immunology, 2018
Betaine is a critical nutrient for mammal health, and has been found to alleviate inflammation by lowering interleukin (IL)-1β secretion; however, the underlying mechanisms by which betaine inhibits IL-1β secretion remain to be uncovered. In this review,
Yaoyao Xia   +11 more
doaj   +1 more source

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

open access: yesFrontiers in Immunology, 2018
Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula   +13 more
doaj   +1 more source

Immunomodulatory Effect of Nigella sativa Extract through the Improvement of IL-1β Level in Balb-c Mice Infected by Methicillin-resistant Staphylococcus aureus

open access: yesJurnal Kedokteran Brawijaya, 2020
Nigella sativa (NS) has been used for many years as an anti-bacterial herbal treatment, such as Methicillin-resistant Staphylococcus aureus, but the mechanism in bacterial elimination is still unknown. IL-1β is a proinflammatory cytokine that helps the immune system eliminate microbes when it enters the body. The purpose of this study was to prove the
Galuh Yulieta Nitihapsari   +2 more
openaire   +2 more sources

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

open access: yeseLife, 2015
Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells.
Min Zhang   +4 more
doaj   +1 more source

Interleukin-1β-Induced Promatrilysin Expression is Mediated by NFκB-Regulated Synthesis of Interleukin-6 in the Prostate Carcinoma Cell Line, LNCaP

open access: yesNeoplasia: An International Journal for Oncology Research, 2001
Previously, our laboratory showed that interleukin-1β (IL-1β) secreted by lipopolysaccharide-activated monocytes induces promatrilysin expression in the prostate carcinoma cell line, LNCaP.
Mimi Suzanne Maliner-Stratton   +4 more
doaj   +1 more source

Modulation of human polymorphonuclear leukocyte chemotaxis and superoxide anion production byPseudomonas aeruginosaexoproducts, IL-1β and piroxicam [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 1995
Whereas addition of 200 ng ml-1 exotoxin A (exoA) did not modify PMNL chemotaxis, 20 U ml-1 human recombinant interleukin-1 beta (hrIL-1 beta) primed polymorphonuclear leukocytes (PMNL) for migration towards Pseudomonas aeruginosa peptide chemotactins (PAPCs).
P A, Fontán   +3 more
openaire   +2 more sources

The In Situ Expression of IL-6 and IL-1? in breast cancer patients

open access: yesIraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
Breast cancer is the second most common cancer in women world. Multiple Cytokines appear to have a dominant role in human breast cancer formation. Estimation of the in situ expression of  IL-6 and IL-1β in breast cancer patients. A sixty patients with breast cancer BC were divided into two clinical subgroups, (30) with malignant breast cancer MBC and (
Amal H. Salman   +2 more
openaire   +3 more sources

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