Results 31 to 40 of about 6,778,674 (329)
Peran Magnesium Sulfat dalam Menurunkan Kadar TNF-α dan IL-1β pada Bayi Prematur
Jurnal Kedokteran Brawijaya, 2017 Prematuritas menyebabkan mortalitas dan morbiditas neonatus yaitu cerebral palsy (CP), gangguan kognitif dan gangguan tingkah laku. Sitokin proinflamasi TNF-α dan IL-1β diduga secara signifikan meningkat pada bayi prematur. Magnesium sulfat (MgSO4) diduga dapat sebagai neuroprotektor terhadap otak janin, melindungi jaringan terhadap aktivitas radikal
Sri Sulistyowati +3 more
openaire +2 more sources
Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms
Frontiers in Immunology, 2018 Betaine is a critical nutrient for mammal health, and has been found to alleviate inflammation by lowering interleukin (IL)-1β secretion; however, the underlying mechanisms by which betaine inhibits IL-1β secretion remain to be uncovered. In this review,
Yaoyao Xia +11 more
doaj +1 more source
Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils
Frontiers in Immunology, 2018 Interleukin-1β (IL-1β), a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established.
Leonardo Iula +13 more
doaj +1 more source
Jurnal Kedokteran Brawijaya, 2020 Nigella sativa (NS) has been used for many years as an anti-bacterial herbal treatment, such as Methicillin-resistant Staphylococcus aureus, but the mechanism in bacterial elimination is still unknown. IL-1β is a proinflammatory cytokine that helps the immune system eliminate microbes when it enters the body. The purpose of this study was to prove the
Galuh Yulieta Nitihapsari +2 more
openaire +2 more sources
Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia [PDF]
, 2009 Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core +1 more source
Journal of the American College of Cardiology, 2018 Background Recent studies have shown that hematopoietic stem cells can undergo clonal expansion due to somatic mutations in leukemia-related genes, leading to an age-dependent accumulation of mutant leukocytes in the blood.
S. Sano +11 more
semanticscholar +1 more source
TUMOR CELL-DERIVED IL-1β PROMOTES DESMOPLASIA AND IMMUNE SUPPRESSION IN PANCREATIC CANCER
Cancer Research, 2020 Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy typified by a highly stromal and weakly immunogenic tumor microenvironment that promotes tumor evolution and contributes to therapeutic resistance.
Shipra Das +4 more
semanticscholar +1 more source
IL-1β-induced IL-8 release and IL-8 mRNA expression in canine dermal fibroblasts.
, 2021 Time-dependent increase in IL-8 protein release (a) and IL-8 mRNA expression levels (b) in cells treated with (closed circle) or without (open circle) canine recombinant IL-1β (100 pM).
Taku Kitanaka (3350276) +9 more
core +1 more source
Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion
eLife, 2015 Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells.
Min Zhang +4 more
doaj +1 more source
Understanding the mechanism of IL-1β secretion
Cytokine & growth factor reviews, 2011 The cytokine interleukin-1β (IL-1β) is a key mediator of the inflammatory response. Essential for the host-response and resistance to pathogens, it also exacerbates damage during chronic disease and acute tissue injury.
G. López-Castejón, D. Brough
semanticscholar +1 more source