Results 31 to 40 of about 3,308,702 (244)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source
, 2020 There is growing evidence that inflammation underpins many common diseases. Inflammatory/immunomodulatory/immune mediators, such as cytokines, are key modulators of inflammation and mediate both immune cell recruitment and complex intracellular ...
Simonova, G +6 more
core +1 more source
IL-17 and IL-1β stimulate ERK and STAT3 in SFs.
, 2021 Flow cytometric analysis of (A) ERK and (B) STAT3 activation, determining the relative expression of dually phosphorylated versus total ERK or phosphorylated STAT3 versus total STAT3 expression, following incubation of Naïve-SFs in medium alone or ...
Felicity E. Lumb (8566887) +9 more
core +1 more source
Cell Reports, 2018 Summary: IL-1β requires processing by caspase-1 to generate the active, pro-inflammatory cytokine. Acute IL-1β secretion from inflammasome-activated macrophages requires caspase-1-dependent GSDMD cleavage, which also induces pyroptosis.
Mercedes Monteleone +13 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
, 2017 Cells isolated from lesions or PBMC obtained from L. braziliensis patients were stained for flow cytometry directly ex vivo and depicted are (a) IL-1β+ CD11b+ cells (b) IL-1β expression within CD68+ (macrophages and monocytes) or CD66b+ (granulocytes) in
Daniel P. Beiting (434631) +7 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
IL-1β aggravates mycolactone-driven endothelial dysfunction.
, 2022 HDMECs (A) or HDLECs (B) were exposed to different concentrations of mycolactone (MYC), and/or IL-1β for 24 hours, then lysed and subjected to immunoblotting.
Joy Ogbechi (546561) +8 more
core +1 more source
Iatreia, 2001 La paracoccidioidomicosis (PCM) es una micosis sistémica restringida a América Latina y producida por la inhalación de las conidias del hongo dimórfico Paracoccidioides brasilienis (Pb) (1).
Luz Elena Cano +4 more
doaj
PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes[S]
Journal of Lipid Research, 2014 This study examined the role of interleukin (IL)-1 receptor-associated kinase (IRAK) and protein kinase C (PKC) in oxidized LDL (Ox-LDL)-induced monocyte IL-1β production.
Rajiv Lochan Tiwari +9 more
doaj +1 more source