Results 31 to 40 of about 4,734,962 (279)

Evaluation of IL-1β and TNF-α expression and periodontitis under the influence of orthodontic appliances with minocycline

Cellular and Molecular Biology, 2020
The current experiment was carried out to observe and analyze the effects of three orthodontic appliances combined with minocycline on periodontitis and inflammatory factors of gingival crevicular fluid. the patients included in this study were 180 patients with dental crowding treated in our hospital.
Jingjing, Zhang, Suqing, Qi, Weican, Chen, Lin, Liu, Hongwei, Hui   +4 more
openaire   +3 more sources

The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages [PDF]

Scientific Reports, 2019
Abstract Inflammation and metabolism are intricately linked during inflammatory diseases in which activation of the nucleotide-binding domain–like receptors Family Pyrin Domain Containing 3 (NLRP3) inflammasome, an innate immune sensor, is critical.
Orla M. Finucane, Jamie Sugrue, Ana Rubio-Araiz, Marie-Victoire Guillot-Sestier, Marina A. Lynch   +4 more
openaire   +4 more sources

Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

Journal of Neuroinflammation, 2019
Background Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague.
Yi Sun, Jiangjun Ma, Dongfang Li, Pinggan Li, Xiaolin Zhou, Yu Li, Zhanwen He, Lijun Qin, Liyang Liang, Xiangyang Luo   +9 more
doaj   +1 more source

TNIP1 regulates myddosome dynamics during IL-1β signaling [PDF]

, 2023
Die Interleukin 1β (IL-1β) vermittelte Signaltransduktion ist für die akute Entzündung von entscheidender Bedeutung, muss aber gleichzeitig streng reguliert werden.
Gerpott, Fenja Helga Ursel
core   +1 more source

Interleukin-1β-Induced Promatrilysin Expression is Mediated by NFκB-Regulated Synthesis of Interleukin-6 in the Prostate Carcinoma Cell Line, LNCaP

Neoplasia: An International Journal for Oncology Research, 2001
Previously, our laboratory showed that interleukin-1β (IL-1β) secreted by lipopolysaccharide-activated monocytes induces promatrilysin expression in the prostate carcinoma cell line, LNCaP.
Mimi Suzanne Maliner-Stratton, Russell D. Klein, Thirupandiyur S. Udayakumar, Raymond B. Nagle, George Timothy Bowden   +4 more
doaj   +1 more source

Trimeric form of intracellular ATP synthase subunit β of Aggregatibacter actinomycetemcomitans binds human interleukin-1β. [PDF]

PLoS ONE, 2011
Bacterial biofilms resist host defenses and antibiotics partly because of their decreased metabolism. Some bacteria use proinflammatory cytokines, such as interleukin (IL)-1β, as cues to promote biofilm formation and to alter virulence.
Annamari Paino, Heidi Tuominen, Mari Jääskeläinen, Jonna Alanko, Jari Nuutila, Sirkka E Asikainen, Lauri J Pelliniemi, Marja T Pöllänen, Casey Chen, Riikka Ihalin   +9 more
doaj   +1 more source

IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH

Scientific Reports, 2023
Interleukin-1β (IL-1β) is a key mediator of non-alcoholic steatohepatitis (NASH), a chronic liver disease, and of systemic inflammation-driven aging.
Dániel Kucsera, Viktória E. Tóth, Nabil V. Sayour, Tamás Kovács, Tamás G. Gergely, Mihály Ruppert, Tamás Radovits, Alexandra Fábián, Attila Kovács, Béla Merkely, Péter Ferdinandy, Zoltán V. Varga   +11 more
doaj   +1 more source

A novel histone deacetylase inhibitor prevents IL-1β induced metabolic dysfunction in pancreatic β-cells [PDF]

Journal of Cellular and Molecular Medicine, 2009
AbstractThe histone deacetylase (HDAC) inhibitor trichostatin A (TSA) has recently been shown to inhibit deleterious effects of cytokines on β‐cells, but it is unable to protect β‐cells from death due to its own cytotoxicity. Herein, we investigated novel HDAC inhibitors for their cytoprotective effects against IL‐1β‐induced damage to isolated β‐cells.
Laura, Susick, Thulani, Senanayake, Rajakrishnan, Veluthakal, Patrick M, Woster, Anjaneyulu, Kowluru   +4 more
openaire   +3 more sources

Effects of interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α ) on dopamine of the cerebral palsy

Asian Journal of Tropical Biotechnology, 2004
The caused of disability on cerebral palsy is unknown, but the human cerebral hypoxic, which affected to the motor cortex and motor pathways in the brain is believed cause of it. The major clinical manifestations are abnormality of movements and posture patterns. The immunity against the cerebral palsy (CP) is unknown, but interleukine-1β (IL-1β) and
openaire   +1 more source

IL-1β processing by MMP-7.

, 2016
(A) Gene expression profiling identified Mmp7 as one of the top up-regulated gene in Asc-/- and Nlrp3-/- mice with bladder pathology (CFT073 infected mice, 7 days). Log2 fold change of Mmp7 expression levels in individual mice are shown relative to the H&
Björn Wullt (243099), Caterina Cafaro (3211710), Karoly Nagy (3211707), Gustav Rydström (3211716), Manoj Puthia (3211725), Aftab Nadeem (3211719), Nina A. Filenko (232011), Daniel S. C. Butler (3211722), Ines Ambite (3211713), Catharina Svanborg (67921), Thomas Miethke (197637)   +10 more
core   +1 more source