Results 61 to 70 of about 530,867 (277)
Is interleukin-1 beta a culprit in macrophage-adipocyte crosstalk in obesity? [PDF]
, 2015 Adipose tissue remodeling occurs in obesity, characterized by adipocyte hypertrophy and increased infiltration of macrophages which also shift to a proinflammatory phenotype.
Bing, Chen
core +1 more source
Majalah Kedokteran Andalas, 2021 Tujuan penelitian ini adalah untuk menganalisis pengaruh dari Mesenchymal Stem Cell Wharton’s Jelly (MSC-WJ) terhadap ekspresi gen IL-1β dan Ryr3 pada otak tikus sebagai hewan model Alzheimer’s disease. Metode yang digunakan untuk mendeteksi ekspresi gen IL-1β dan Ryr3 dilakukan secara kuantitatif menggunakan Real-Time PCR.
openaire +2 more sources
IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway [PDF]
PLoS ONE, 2011 Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the catabolic actions of cytokines may have therapeutic potential in the treatment of OA.
Montaseri A. +6 more
openaire +6 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Iatreia, 2001 La paracoccidioidomicosis (PCM) es una micosis sistémica restringida a América Latina y producida por la inhalación de las conidias del hongo dimórfico Paracoccidioides brasilienis (Pb) (1).
Luz Elena Cano +4 more
doaj
PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes[S]
Journal of Lipid Research, 2014 This study examined the role of interleukin (IL)-1 receptor-associated kinase (IRAK) and protein kinase C (PKC) in oxidized LDL (Ox-LDL)-induced monocyte IL-1β production.
Rajiv Lochan Tiwari +9 more
doaj +1 more source
Brain Perivascular Macrophages Do Not Mediate Interleukin-1-Induced Sickness Behavior in Rats
Pharmaceuticals, 2021 Sickness behavior, characterized by on overall reduction in behavioral activity, is commonly observed after bacterial infection. Sickness behavior can also be induced by the peripheral administration of Gram-negative bacterial lipopolysaccharide (LPS) or
Léa Chaskiel +2 more
doaj +1 more source
Oncotarget, 2018 // Zhuoya Wang 1, * , Weiwei Wang 1, * , Yun Hou 2 , Aiping Zhang 1 , Guoyan Wang 3 , Junzhu Yi 1 , Qiang Fu 1 and Xiying Luan 1, 4 1 Department of Immunology, Binzhou Medical University, Shandong Province, Yantai 264003, People’s Republic of China 2 Department of Histology and Embryology, Binzhou Medical University, Shandong Province ...
Zhuoya Wang +15 more
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Correlation b etween IL - 1β and IL - 10 Levels in Estimating t he Risk of Febrile Seizures
Journal of Tropical Life Science, 2014 Febrile seizures are the most-common form of seizures in children with fever and evidence from clinical and experimental studies suggests the potential role of immune generated products in their genesis.
Gunawan A +4 more
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