Results 1 to 10 of about 1,115,069 (312)

Memory Macrophages

International Journal of Molecular Sciences, 2022
Immunological memory is a crucial part of the immune defense that allows organisms to respond against previously encountered pathogens or other harmful factors. Immunological memory is based on the establishment of epigenetic modifications of the genome.
Malgorzata Kloc, Jacek Z. Kubiak, Robert Zdanowski, Rafik M. Ghobrial   +3 more
openaire   +2 more sources

Homegrown Macrophages [PDF]

Immunity, 2016
Macrophages residing in different organs have diverse gene-expression programs. Mass et al. (2016) propose that this diversity develops "at home"-within those organs-after the recruitment of a common precursor that had not made prior commitments to diversity.
Ki-Wook, Kim, Nan, Zhang, Kyunghee, Choi, Gwendalyn J, Randolph   +3 more
openaire   +2 more sources

Heterogeneity of Bovine Peripheral Blood Monocytes

Frontiers in Immunology, 2017
Peripheral blood monocytes of several species can be divided into different subpopulations with distinct phenotypic and functional properties. Herein, we aim at reviewing published work regarding the heterogeneity of the recently characterized bovine ...
Jamal Hussen, Jamal Hussen, Hans-Joachim Schuberth   +2 more
doaj   +1 more source

BMAL2 promotes eCIRP-induced macrophage endotoxin tolerance

Frontiers in Immunology
BackgroundThe disruption of the circadian clock is associated with inflammatory and immunological disorders. BMAL2, a critical circadian protein, forms a dimer with CLOCK, activating transcription. Extracellular cold-inducible RNA-binding protein (eCIRP),
Mian Zhou, Monowar Aziz, Monowar Aziz, Jingsong Li, Alok Jha, Gaifeng Ma, Atsushi Murao, Ping Wang, Ping Wang   +8 more
doaj   +1 more source

Activation of Murine Immune Cells upon Co-culture with Plasma-treated B16F10 Melanoma Cells

Applied Sciences, 2019
Recent advances in melanoma therapy increased median survival in patients. However, death rates are still high, motivating the need of novel avenues in melanoma treatment.
Katrin Rödder, Juliane Moritz, Vandana Miller, Klaus-Dieter Weltmann, Hans-Robert Metelmann, Rajesh Gandhirajan, Sander Bekeschus   +6 more
doaj   +1 more source

Characterization of novel double-reporter strains of Mycobacterium abscessus for drug discovery: a study in mScarlet

Microbiology Spectrum
Mycobacterium abscessus (Mab) is an emerging pathogen that poses a severe health threat, especially in people with cystic fibrosis and other chronic lung diseases.
Clara M. Bento, Kevin van Calster, Tatiana Piller, Gabriel S. Oliveira, Linda de Vooght, Davie Cappoen, Paul Cos, M. Salomé Gomes, Tânia Silva   +8 more
doaj   +1 more source

GRN Activates TNFR2 to Promote Macrophage M2 Polarization Aggravating Mycobacterium Tuberculosis Infection

Frontiers in Bioscience-Landmark
Background: The polarization of macrophages plays a critical role in the immune response to infectious diseases, with M2 polarization shown to be particularly important in various pathological processes.
Bingling Zhang, Lan Xiang, Jun Chen, Jun Zhang, Renliu Dong, Guolun Mo, Feng Wu   +6 more
doaj   +1 more source

The Role of Breastmilk in Macrophage-Tumour Cell Interactions in Postpartum Breast Cancer

Frontiers in Bioscience-Landmark
Background: Lactation is associated with long-term reduced risk of breast cancer. However, there is a transient increased risk of breast cancer in the 5 to 10 years postpartum and this is associated with a high incidence of metastasis ...
Reza Maleki, Amna Ghith, Hanieh Heydarlou, Luke E Grzeskowiak, Wendy V Ingman   +4 more
doaj   +1 more source

Dynamic Roles and Expanding Diversity of Adipose Tissue Macrophages in Obesity

Journal of Obesity & Metabolic Syndrome
Adipose tissue macrophages (ATMs) are key regulators of adipose tissue (AT) inflammation and insulin resistance in obesity, and the traditional M1/M2 characterization of ATMs is inadequate for capturing their diversity in obese conditions.
Shindy Soedono, Vivi Julietta, Hadia Nawaz, Kae Won Cho   +3 more
doaj   +1 more source

The oxidant-antioxidant imbalance was involved in the pathogenesis of chronic rhinosinusitis with nasal polyps

Frontiers in Immunology
BackgroundAlthough oxidative stress is involved in the pathophysiological process of chronic rhinosinusitis with nasal polyps (CRSwNP), the specific underlying mechanism is still unclear.
Jing Zhou, Jing Zhou, Jiao Zhou, Ruowu Liu, Ruowu Liu, Yafeng Liu, Yafeng Liu, Juan Meng, Juan Meng, Qiao Wen, Qiao Wen, Yirui Luo, Shixi Liu, Shixi Liu, Huabin Li, Luo Ba, Jintao Du, Jintao Du   +17 more
doaj   +1 more source