Results 31 to 40 of about 1,115,069 (312)
Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core +6 more sources
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni +12 more
doaj +1 more source
Effects of Scutellariae Radix-acupuncture solution On Anti-inflammatory in RAW 264.7 macrophages
Objective : Recently, Herbal-acupuncture therapeutics has been used for the treatment of inflammatory diseases such as rheumatoid arthritis. Especially, we have been interested in chemical mediators concerned with inflammation such as prostaglandin ...
Young-kwang Choi +5 more
doaj +1 more source
The Peculiar Characteristics of Fish Type I Interferons
Antiviral type I interferons (IFNs) have been discovered in fish. Genomic studies revealed their considerable number in many species; some genes encode secreted and non-secreted isoforms.
Pierre Boudinot +3 more
doaj +1 more source
Major roles of kupffer cells and macrophages in NAFLD development
Non-alcoholic fatty liver disease (NAFLD) is an important public health problem with growing numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of NAFLD due to various factors.
Soo-Jeung Park +5 more
doaj +1 more source
Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Ebermann, L. +37 more
core +2 more sources
Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado +5 more
doaj +1 more source
The elegance of a macrophage [PDF]
In the latest issue of Nature Immunology, Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ (IFN-γ) and interleukin 4 (IL-4) antagonistic signals on macrophage transcriptional and epigenetic profiles and, interestingly, identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized ...
Maria, De Santis +2 more
openaire +2 more sources
"Re-educating" tumor-associated macrophages by targeting NF-kappaB [PDF]
The nuclear factor kappaB (NF-kappaB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-kappaB in cancer in maintaining the immunosuppressive phenotype of tumor-associated ...
Balkwill, F.R. +23 more
core +1 more source
Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
K James +7 more
core +1 more source

