Results 31 to 40 of about 1,115,069 (312)

Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]

open access: yes, 2004
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core   +6 more sources

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

open access: yesDisease Models & Mechanisms, 2017
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni   +12 more
doaj   +1 more source

Effects of Scutellariae Radix-acupuncture solution On Anti-inflammatory in RAW 264.7 macrophages

open access: yesJournal of Pharmacopuncture, 2003
Objective : Recently, Herbal-acupuncture therapeutics has been used for the treatment of inflammatory diseases such as rheumatoid arthritis. Especially, we have been interested in chemical mediators concerned with inflammation such as prostaglandin ...
Young-kwang Choi   +5 more
doaj   +1 more source

The Peculiar Characteristics of Fish Type I Interferons

open access: yesViruses, 2016
Antiviral type I interferons (IFNs) have been discovered in fish. Genomic studies revealed their considerable number in many species; some genes encode secreted and non-secreted isoforms.
Pierre Boudinot   +3 more
doaj   +1 more source

Major roles of kupffer cells and macrophages in NAFLD development

open access: yesFrontiers in Endocrinology, 2023
Non-alcoholic fatty liver disease (NAFLD) is an important public health problem with growing numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of NAFLD due to various factors.
Soo-Jeung Park   +5 more
doaj   +1 more source

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

open access: yes, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Ebermann, L.   +37 more
core   +2 more sources

Soybean Meal-Induced Intestinal Inflammation in Zebrafish Is T Cell-Dependent and Has a Th17 Cytokine Profile

open access: yesFrontiers in Immunology, 2019
Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado   +5 more
doaj   +1 more source

The elegance of a macrophage [PDF]

open access: yesCellular & Molecular Immunology, 2017
In the latest issue of Nature Immunology, Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ (IFN-γ) and interleukin 4 (IL-4) antagonistic signals on macrophage transcriptional and epigenetic profiles and, interestingly, identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized ...
Maria, De Santis   +2 more
openaire   +2 more sources

"Re-educating" tumor-associated macrophages by targeting NF-kappaB [PDF]

open access: yes, 2008
The nuclear factor kappaB (NF-kappaB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-kappaB in cancer in maintaining the immunosuppressive phenotype of tumor-associated ...
Balkwill, F.R.   +23 more
core   +1 more source

Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]

open access: yes, 1983
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
K James   +7 more
core   +1 more source

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