Results 41 to 50 of about 1,417,216 (308)

Germination of Aspergillus fumigatus inside avian respiratory macrophages is associated with cytotoxicity [PDF]

, 2012
Although aspergillosis is one of the most common diseases in captive birds, the pathogenesis of avian aspergillosis is poorly known. We studied the role of avian respiratory macrophages as a first line of defense against avian aspergillosis.
D'Herde, Katharina, Ducatelle, Richard, Favoreel, Herman, Haesebrouck, Freddy, Li, Shaoji, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven   +7 more
core   +2 more sources

Macrophage elastase kills bacteria within murine macrophages [PDF]

Nature, 2009
Macrophages are aptly positioned to function as the primary line of defence against invading pathogens in many organs, including the lung and peritoneum. Their ability to phagocytose and clear microorganisms has been well documented. Macrophages possess several substances with which they can kill bacteria, including reactive oxygen species, nitric ...
A McGarry, Houghton, William O, Hartzell, Clinton S, Robbins, F Xavier, Gomis-Rüth, Steven D, Shapiro   +4 more
openaire   +2 more sources

Macrophage Fusion [PDF]

The Journal of Experimental Medicine, 2005
The fusion of cells is a fundamental biological event that is essential for a variety of developmental and homeostatic processes. Fusion is required for the formation of multinucleated osteoclasts and giant cells, although the mechanisms that govern these processes are poorly understood.
openaire   +1 more source

Bidirectional Crosstalk Between Cancer Stem Cells and Immune Cell Subsets

Frontiers in Immunology, 2020
Cancer stem cells (CSCs), also known as tumor-initiating cells, are characterized by an increased capacity for self-renewal, multipotency, and tumor initiation.
Luise Müller, Antje Tunger, Antje Tunger, Ioana Plesca, Rebekka Wehner, Rebekka Wehner, Rebekka Wehner, Achim Temme, Achim Temme, Achim Temme, Dana Westphal, Friedegund Meier, Friedegund Meier, Friedegund Meier, Michael Bachmann, Michael Bachmann, Michael Bachmann, Marc Schmitz, Marc Schmitz, Marc Schmitz   +19 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Crosstalk between cancer stem cells and the tumor microenvironment drives progression of premalignant oral epithelium

Frontiers in Oral Health, 2023
Cancer stem cells (CSC) are a subpopulation of cancer cells that exhibit properties of self-renewal and differentiation and have been implicated in metastasis and treatment failures. There is mounting evidence that carcinogen-initiated mucosal epithelial
Peter J. Polverini, Felipe Nör, Jacques E. Nör   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Immune response in glioma’s microenvironment

Innovative Surgical Sciences, 2021
Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma ...
Chen Houminji, Li Ming, Guo Yanwu, Zhong Yongsheng, He Zhuoyi, Xu Yuting, Zou Junjie   +6 more
doaj   +1 more source

The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release [PDF]

, 2013
<p>Objectives: Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial macrophages and thereby promote RA disease pathology remain poorly understood.</
Ananth, Antoniv, Asquith, Asquith, Baeten, Bresnihan, Darren Lee Asquith, Enevold, Feldmann, Fontaine, Gerlag, Haringman, He, Huang, Iain B McInnes, Iwahashi, J Alastair Gracie, Jagtar Singh Nijjar, Jahangier, James H Reilly, Janowski, Kauffmann, Kinne, Koch, Long, Lucy E Ballantine, Manhal Khuder Makdasy, Mariola Kurowska-Stolarska, Mulherin, Ospelt, Pamela B Wright, Radstake, Ridley, Sabina Patel, Sack, Sacre, Sattar, Shauna Kerr, Tamaki, van der Heijden, van Halm, van Sijl, Zhao   +42 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source