Results 21 to 30 of about 1,150,963 (313)

Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages—Potential Implications for Cytokine Storm Syndrome

Vaccines, 2021
The pandemic of the new coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has led to the deaths of more than 1.5 million people worldwide.
Iwona Karwaciak, Anna Sałkowska, Kaja Karaś, Jarosław Dastych, Marcin Ratajewski   +4 more
doaj   +1 more source

Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level

eLife, 2023
The regulation of inflammatory responses is an important intervention in biological function and macrophages play an essential role during inflammation.
Atomu Yamaguchi, Noriaki Maeshige, Hikari Noguchi, Jiawei Yan, Xiaoqi Ma, Mikiko Uemura, Dongming Su, Hiroyo Kondo, Kristopher Sarosiek, Hidemi Fujino   +9 more
doaj   +1 more source

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Journal of Extracellular Vesicles, 2023
Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological
Younggap Lim, Hyun Young Kim, Dohyun Han, Bong‐Kyu Choi   +3 more
doaj   +1 more source

A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death

Frontiers in Immunology, 2018
Enhanced susceptibility to bacterial infection in the days following an acute virus infection such as flu is a major clinical problem. Mouse models have provided major advances in understanding viral-bacterial superinfections, yet interactions of the ...
Laurent Boucontet, Laurent Boucontet, Gabriella Passoni, Gabriella Passoni, Valéry Thiry, Valéry Thiry, Ludovico Maggi, Ludovico Maggi, Philippe Herbomel, Philippe Herbomel, Jean-Pierre Levraud, Jean-Pierre Levraud, Emma Colucci-Guyon, Emma Colucci-Guyon   +13 more
doaj   +1 more source

IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype [PDF]

, 2002
Background"Alternatively-activated" macrophages are found in Th2-mediated inflammatory settings such as nematode infection and allergic pulmonary inflammation.
Nair, Meera G, P'ng Loke, John Parkinson, Parkinson, John, Judith E Allen, Loke, P'ng, Blaxter, Mark, Meera G Nair, Guiliano, David, Mark Blaxter, Allen, Judith E, David Guiliano, Blaxter, M., Allen, J.E., Guiliano, D.B., Loke, P., Parkinson John, Parkinson, J., Allen Judith E, Blaxter Mark, Nair, M.G., Guiliano David, Nair Meera G, Loke P'ng   +23 more
core   +1 more source

The role of macrophage in lung injury, repair and regeneration

生物医学转化, 2023
The risk of lung injury induced by microorganism infection or other physical/chemical insults is high due to the nature that the lung is constantly exposed to microbiota through inhalation. The lung was previously thought to be a highly quiescent tissue,
Ran Linyu, Li Qiang, Wang Feilong
doaj   +1 more source

The Macrophage Paradox [PDF]

Immunity, 2014
Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the body. At sites of infection, macrophages encounter and engulf invading microbes. Accordingly, macrophages possess specialized effector functions to kill or coordinate the elimination of their prey.
Price, Jordan V., Vance, Russell E.
openaire   +2 more sources

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

Frontiers in Immunology, 2017
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin, Elina Aleksejeva, Armel Houel, Valérie Briolat, Valérie Briolat, Corinne Torhy, Aurélie Lunazzi, Jean-Pierre Levraud, Jean-Pierre Levraud, Pierre Boudinot   +9 more
doaj   +1 more source

Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts. [PDF]

, 2012
The inhibition of death-receptor apoptosis is a conserved viral function. The murine cytomegalovirus (MCMV) gene M36 is a sequence and functional homologue of the human cytomegalovirus gene UL36, and it encodes an inhibitor of apoptosis that binds to ...
Čičin-Šain, Luka, Luka Čičin-Šain, Rosaely Casalegno-Garduño (111456), Carlos A Guzmán, Ruzsics, Zsolt, van Rooijen, Nico, Ulrich Koszinowski, Linda Ebermann (111451), Zsolt Ruzsics (75383), Nico van Rooijen, Ulrich Koszinowski (111457), Ruzsics Zsolt, Casalegno-Garduño, Rosaely, Nico van Rooijen (4110211), Koszinowski, Ulrich H., Zsolt Ruzsics, Carlos A. Guzmán (111454), Luka Čičin-Šain (111459), Guzmán, Carlos A., Guzmán Carlos A., Ebermann Linda, Linda Ebermann, Čičin-Šain Luka, Guzmán, Carlos A, Casalegno-Garduño Rosaely, Koszinowski, Ulrich, Rosaely Casalegno-Garduño, Ebermann, Linda, van Rooijen Nico, Koszinowski Ulrich   +29 more
core   +1 more source

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

Disease Models & Mechanisms, 2017
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni, Christelle Langevin, Nuno Palha, Bryan C. Mounce, Valérie Briolat, Pierre Affaticati, Elodie De Job, Jean-Stéphane Joly, Marco Vignuzzi, Maria-Carla Saleh, Philippe Herbomel, Pierre Boudinot, Jean-Pierre Levraud   +12 more
doaj   +1 more source