Results 1 to 10 of about 6,985,758 (299)
Canadian Respiratory Journal, 2022 Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading
Lan Wang +7 more
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Overview of CircRNAs Roles and Mechanisms in Liver Fibrosis
Biomolecules, 2023 Liver fibrosis represents the reversible pathological process with the feature of the over-accumulation of extracellular matrix (ECM) proteins within the liver, which results in the deposition of fibrotic tissues and liver dysfunction. Circular noncoding
Gaiping Wang +6 more
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Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Mottram, Jeremy +3 more
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The correlation of keratin expression with in-vitro epithelial cell line differentiation [PDF]
, 2009 MPhil 2009 QMThe mechanism of transcriptional regulation which allows oral mucosal-specific expression of the human keratin 13 (K13) gene remains unknown.
Aden, Deeqo
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Mitochondrial Dysfunction and Chronic Liver Disease
Current Issues in Molecular Biology, 2022 Mitochondria are generally considered the powerhouse of the cell, a small subcellular organelle that produces most of the cellular energy in the form of adenosine triphosphate (ATP). In addition, mitochondria are involved in various biological functions,
Chunyan Zhang +5 more
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Criticality in Cell Differentiation [PDF]
Journal of Biosciences, 2016 Abstract Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and stochastic components.
Bose, Indrani, Pal, Mainak
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Animal Cells and Systems, 2020 Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair +9 more
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Scientific Reports, 2023 Parkinson’s disease (PD) is the second most common neurodegenerative disease and is characterized by the loss of midbrain dopaminergic neurons. Endocrine disrupting chemicals (EDCs) are active substances that interfere with hormonal signaling. Among EDCs,
Andrea Di Credico +6 more
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Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells [PDF]
, 2015 © 2015 Macmillan Publishers Limited. All rights reserved. microRNA-34a (miR-34a) and sirtuin 1 (SirT1) have been extensively studied in tumour biology and longevityaging, but little is known about their functional roles in smooth muscle cell (SMC ...
L A Luong +35 more
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DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
Genetics and Molecular Biology, 2014 Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li +3 more
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