Non-genetic heterogeneity criticality and cell differentiation
, 2014 The different cell types in a living organism acquire their identity through the process of cell differentiation in which the multipotent progenitor cells differentiate into distinct cell types.
Bose, Indrani +2 more
core +1 more source
Adult human biliary tree stem cells differentiate to β-pancreatic islet cells by treatment with a recombinant human Pdx1 peptide [PDF]
, 2015 Generation of β-pancreatic cells represents a major goal in research. The aim of this study was to explore a protein-based strategy to induce differentiation of human biliary tree stem cells (hBTSCs) towards β-pancreatic cells.
Alvaro, Domenico +15 more
core +7 more sources
Micro- and nanoengineering approaches to control stem cell-biomaterial interactions. [PDF]
, 2011 As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem
Dokmeci, Mehmet R +4 more
core +2 more sources
The proteome of the heterocyst cell wall in Anabaena sp. PCC 7120 [PDF]
, 2007 Anabaena sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation.
Berg, Matthias +8 more
core +1 more source
Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
core +2 more sources
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation [PDF]
, 2019 Yes-associated protein (YAP) is a transcriptional co-factor involved in many cell processes, including development, proliferation, stemness, differentiation, and tumorigenesis.
Amicone, Laura +8 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Nature Communications, 2018 Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.
Guoliang Lyu +10 more
doaj +1 more source
Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation
FEBS Open Bio, 2020 Myogenesis is a physiological process which involves the proliferation of myoblasts and their differentiation into multinucleated myotubes, which constitute the future muscle fibers.
Caroline Vergé +5 more
doaj +1 more source
High-Fat Diet Related Lung Fibrosis-Epigenetic Regulation Matters
Biomolecules, 2023 Pulmonary fibrosis (PF) is an interstitial lung disease characterized by the destruction of the pulmonary parenchyma caused by excessive extracellular matrix deposition.
Juntang Yang +4 more
doaj +1 more source