Results 71 to 80 of about 3,308,702 (244)

IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.

open access: yes, 2011
Earlier, we have shown that GM-CSF-exposed CD8α- DCs that express low levels of pro-inflammatory cytokines IL-12 and IL-1β can induce Foxp3+ Tregs leading to suppression of autoimmunity.
Prabhakar Bellur S.   +19 more
core   +1 more source

Interleukin-1β promotes interleulin-6 expression via ERK1/2 signaling pathway in canine dermal fibroblasts.

open access: yesPLoS ONE, 2019
Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the immune response and inflammation. In this study, we investigated effect of the proinflammatory cytokine interleukin-1β (IL-1β) on IL-6 expression in canine dermal ...
Nanako Kitanaka   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

open access: yes, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core  

Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome. [PDF]

open access: yes, 2011
The use of antimycotic drugs in fungal infections is based on the concept that they suppress fungal growth by a direct killing effect. However, amphotericin and nystatin have been reported to also trigger interleukin-1β (IL-1β) secretion in monocytes but
Rupanagudi Khader Valli   +15 more
core   +1 more source

IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

open access: yesRespiratory Research, 2018
Background Viral-induced asthma exacerbations, which exhibit both Th1-type neutrophilia and Th2-type inflammation, associate with secretion of Interleukin (IL)-1β. IL-1β induces neutrophilic inflammation. It may also increase Th2-type cytokine expression.
Irma Mahmutovic Persson   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Alternatív bioaktív hatóanyagok hatása a brojlercsirkék IL-1β génexpressziójára és viselkedésére

open access: yes, 2018
A dolgozatban különbözö alternatív bioaktív hatóanyagok brojler csirkékre gyakorolt hatásának vizsgálata olvasható. Ezeket a hatóanyagokat (β- glükán, karotinoid, fruktooligoszacharid, probiotikum, flavonoid, antocianin) a takarmányba keverve vizsgáltuk ...
Balogh, Kristóf
core  

IL-1β and OPN mRNA expression in RSV infected cells.

open access: yes, 2018
HEp-2 and HEK-293 cells were mock infected or infected with 1 MOI of RSV-L19F. RNA was isolated at 24, 48 and 72 hpi. (A-C) Expression levels of RSV-N, IL-1β and OPN were determined by qPCR. Results are presented as fold-change in expression of RSV-N, IL-
Michael B. Cheung (3190440)   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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