Results 91 to 100 of about 6,778,674 (329)

IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells. [PDF]

, 2011
Earlier, we have shown that GM-CSF-exposed CD8α- DCs that express low levels of pro-inflammatory cytokines IL-12 and IL-1β can induce Foxp3+ Tregs leading to suppression of autoimmunity.
Prabhakar Bellur S., Ganesh Balaji B., Jianrong Sheng, Vasu Chenthamarakshan, Balaji B Ganesh, Palash Bhattacharya (214331), Chenthamarakshan Vasu (214342), Gopisetty Anupama, Chenthamarakshan Vasu, Palash Bhattacharya, Anupama Gopisetty (214334), Jianrong Sheng (214337), Bellur S Prabhakar, Anupama Gopisetty, Balaji B. Ganesh (7946876), Bhattacharya Palash, Bellur S. Prabhakar, Bellur S. Prabhakar (117610), Balaji B. Ganesh, Sheng Jianrong   +19 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

La interleucina-1β aumenta la muerte neuronal en el giro dentado del hipocampo asociada al estado epiléptico en la rata en desarrollo

Neurología, 2017
Resumen: Introducción: La interleucina 1β (IL-1β) aumenta la muerte neuronal necrótica debido al estado epiléptico (EE) en el área CA1 del hipocampo de ratas en desarrollo; sin embargo, se desconoce si ejerce un efecto similar en el giro dentado (GD ...
C. Rincón-López, A. Tlapa-Pale, J.-S. Medel-Matus, J. Martínez-Quiroz, J.F. Rodríguez-Landa, M.-L. López-Meraz   +5 more
doaj   +1 more source

Alteration of dopamine, homovanillic acid (HVA) with interleukine-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in cerebral palsy

Biodiversitas Journal of Biological Diversity, 1970
Now, diagnosis of cerebral palsy base only on clinical finding without involve the alteration of the neurochemistry cause by cerebral hypoxic, although cerebral palsy is a syndrome cause by cerebral hypoxic; so, the accuracy diagnosis of this disease is very low.
openaire   +2 more sources

Additional file 2: Table S1. of IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

, 2018
Commercially available primer sequences for genes analysed with RT-qPCR. (DOCX 13 kb)
Mahmutovic Persson, Irma, Menzel, Mandy, Ramu, Sangeetha, Cerps, Samuel, Akbarshahi, Hamid, Uller, Lena   +5 more
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Additional file 1: Figure S1. of Human iPSC-derived chondrocytes mimic juvenile chondrocyte function for the dual advantage of increased proliferation and resistance to IL-1β

, 2017
Global gene expression patterns in hiChondrocytes and juvenile chondrocytes are distinct from adult chondrocytes: (a) scheme for a step-wise hiChondrocyte differentiation from hiPSC using defined growth factors, (b) cell proliferation kinetics of hiChondrocytes, adult chondrocytes, and juvenile chondrocytes over 24, 48, and 96 hours, (c)heatmap ...
Lee, Jieun, Smeriglio, Piera, Chu, Constance, Bhutani, Nidhi   +3 more
openaire   +1 more source

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]

, 2005
Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Uzan, Benjamin, Lioté, Frédéric, Rey, Christian, Ea, Hang-Korng   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A moonlighting function of tumoral interleukin-1β precursor promotes metastasis via RACK1-mediated actin remodeling

Nature Communications
Interleukin-1β (IL-1β) is a key inflammatory mediator in cancer. Its precursor, Pro-IL-1β, is conventionally considered inactive. Here we demonstrate that head and neck squamous cell carcinoma (HNSCC) cells exhibit significantly elevated Pro-IL-1β ...
Quanzhu Chen, Pan Wu, Jing Cai, Xingxing Lu, Zhaojian Gong, Pan Chen, Zhaoyang Zeng, Guiyuan Li, Wei Xiong, Mei Yi, Bo Xiang   +10 more
doaj   +1 more source