Results 111 to 120 of about 6,778,674 (329)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Frontiers in Immunology, 2020 Helicobacter pylori is a gram-negative, microaerophilic, and spiral-shaped bacterium and causes gastrointestinal diseases in human. IL-1β is a representative cytokine produced in innate immune cells and is considered to be a key factor in the development
Ah-Ra Jang +12 more
doaj +1 more source
Journal of Neuroinflammation, 2019 Chronic pain is a major clinical problem with limited treatment options. Previous studies have demonstrated that activation of adenosine monophosphate-activated protein kinase (AMPK) can attenuate neuropathic pain.
Hong-chun Xiang +11 more
semanticscholar +1 more source
, 2018 Sequences of the primers used in this study. (DOC 32Â kb)
Quan, Juan-Hua +7 more
openaire +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Inflammation and immunosuppression are dominant features of cancer progression. In the tumor microenvironment, macrophages produce interleukin-1β (IL-1β), which subsequently recruits myeloid cells from the bone marrow.
I. Kaplanov +8 more
semanticscholar +1 more source
Targeted anti–IL-1β platelet microparticles for cardiac detoxing and repair
Science Advances, 2020 Platelet microparticles are used to deliver IL-1β antibodies to myocardial infarction for cardiac detoxing and repair. An acute myocardial infarction (AMI) induces a sterile inflammatory response that facilitates further heart injury and promotes adverse
Zhen-Hua Li +5 more
semanticscholar +1 more source
IL-1β aggravates mycolactone-driven endothelial dysfunction.
, 2022 HDMECs (A) or HDLECs (B) were exposed to different concentrations of mycolactone (MYC), and/or IL-1β for 24 hours, then lysed and subjected to immunoblotting.
Joy Ogbechi (546561) +8 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
PLoS ONE, 2019 Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the immune response and inflammation. In this study, we investigated effect of the proinflammatory cytokine interleukin-1β (IL-1β) on IL-6 expression in canine dermal ...
Nanako Kitanaka +7 more
doaj +1 more source