Results 1 to 10 of about 1,851,762 (241)
Role of IL-6 gene polymorphisms in children with autism spectrum disorders [PDF]
Italian Journal of PediatricsBackground Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by impairment in social interaction, and communication skills, along with restricted or repetitive behaviors.
Noha M. Abdullah +5 more
doaj +2 more sources
Journal of Inflammation Research, 2021 Joanna Kamińska,1 Violetta Dymicka-Piekarska,1 Robert Chrzanowski,2 Karol Sawicki,2 Anna J Milewska,3 Justyna Zińczuk,1 Marzena Tylicka,4 Marek Jadeszko,2 Zenon Mariak,2 Ewa M Kratz,5 Joanna Matowicka-Karna,1 Johannes Kornhuber,6 Piotr ...
Kamińska J +13 more
doaj +4 more sources
IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6 [PDF]
International Journal of Biological Sciences, 2012 Interleukin-6 (IL-6) is a cytokine with many activities. It has functions in the regulation of the immune system and the nervous system. Furthermore, IL-6 is involved in liver regeneration and in the metabolic control of the body.
Stefan Rose-John
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The role of IL-6 and IL-6 blockade in COVID-19 [PDF]
Expert Review of Clinical Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a dysregulated hyperinflammatory response.Authors review evidence on IL-6 and IL-6 blockade in coronavirus disease 2019 (COVID-19) and discuss the pathophysiological and prognostic roles of this cytokine and the clinical impact of pharmacological blockade of IL-6 .
Nicola Potere +7 more
openaire +5 more sources
A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer
Membranes, 2021 Colorectal cancer (CRC) is the third most frequent cancer worldwide and the second greatest cause of cancer deaths. About 75% of all CRCs are sporadic cancers and arise following somatic mutations, while about 10% are hereditary cancers caused by ...
Mimmo Turano +4 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundThe use of IL-6 blockers in COVID-19 hospitalized patients has been associated with a reduction in mortality compared to standard care. However, many uncertainties remain pertaining to optimal intervention time, administration schedule, and ...
Rosario García-Vicuña +15 more
doaj +1 more source
Efficacy Of Tocilizumab On Critical Intensive Care Unit COVID-19 Patients: Retrospective Study Among Egyptian Armed Forces Hospitals. [PDF]
Arcades of Medicine, 2023 Background: Since the first reports of COVID-19 disease, it has become clear that acute respiratory distress syndrome was responsible for a significant number of deaths among infected patients.
Mahmoud Hussien +5 more
doaj +1 more source
International Journal of Infectious Diseases, 2022 Objectives: This study aimed to assess if tocilizumab (TCZ) timing is associated with improved survival. Material and methods: Data obtained from adult patients with moderate/severe/critical COVID-19 and treated with TCZ, who were admitted to the ...
Amanda Radulescu +2 more
doaj +1 more source
Indonesian Journal of Chemistry, 2023 The objective of this study was to assess the predictive value of inflammatory biomarkers in COVID-19 patients, namely the CRP/albumin ratio (CAR), interleukin 6 (IL-6), IL-6/lymphocyte ratio (IL-6/LY), and neutrophil/lymphocyte ratio (NLR).
Agustin Iskandar +6 more
doaj +1 more source
Interleukin-6 mediates delirium-like phenotypes in a murine model of urinary tract infection
Journal of Neuroinflammation, 2021 Background Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The pathogenesis
Mohammad Harun Rashid +8 more
doaj +1 more source