Results 21 to 30 of about 1,851,762 (241)

Lipoprotein(a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association?

open access: yesAtherosclerosis Plus, 2023
Background and aims: Lipoprotein(a) [Lp(a)] and interleuking-6 (IL-6), an inflammation biomarker, have been established as distinct targets of the residual atherosclerotic cardiovascular disease (ASCVD) risk.
Anastasios Makris   +6 more
doaj   +1 more source

Interleukin (IL-6) Immunotherapy [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2017
Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses.
Toshio, Tanaka   +2 more
openaire   +2 more sources

IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation

open access: yesFrontiers in Immunology, 2022
Elevated levels and enhanced sensing of the pro-inflammatory cytokine interleukin-6 (IL-6) are key features of many autoimmune and inflammatory diseases.
Katharina Lambert   +11 more
doaj   +1 more source

Cytokine gene polymorphisms in lymphoma: Thesis Abstract [PDF]

open access: yesEgyptian Journal of Cancer and Biomedical Research, 2021
Thesis Abstract Several cytokines are known to be involved in the pathogenesis of non-Hodgkin Lymphomas (NHL). Given the importance of understanding the genetic predisposition involved in the pathogenesis of NHL, this work was designed to study the ...
naser Abd El Bary   +3 more
doaj   +1 more source

The role of serum IL-6 changes in evaluation of endometriosis

open access: yesمجلة كلية الطب, 2013
Background:- Endometriosis is a common chronic gynecological disorder characterized by the presence and proliferation of functional endometrial gland and stroma outside the uterine cavity, affecting approximately 10% of reproductive age women. Il-6 level
Tharwa H. Hassan AL-Tai   +2 more
doaj   +1 more source

Carvacrol alleviates the proconvulsive effects of lipopolysaccharide (LPS) and reduces the gene expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-α [PDF]

open access: yesAvicenna Journal of Phytomedicine
Objective: Carvacrol has anti-inflammatory effects. According to the links between inflammatory processes and seizures, this study was designed to investigate the potential effect of carvacrol in reducing seizure severity and involvement of hippocampal ...
Hesamodin Bagheripoor   +2 more
doaj   +1 more source

Phenotypic and Functional Heterogeneity of Low-Density and High-Density Human Lung Macrophages

open access: yesBiomedicines, 2021
Background: Pulmonary macrophages are a highly heterogeneous cell population distributed in different lung compartments. Methods: We separated two subpopulations of macrophages from human lung parenchyma according to flotation over density gradients ...
Barbara Balestrieri   +8 more
doaj   +1 more source

IL-6 and diabetic kidney disease

open access: yesFrontiers in Immunology
Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes associated with high mortality and disability rates. Inflammation has emerged as a key pathological mechanism in DKD, prompting interest in novel therapeutic approaches ...
Lei Zhang, Futian Xu, Liyan Hou
doaj   +1 more source

The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer

open access: yesJournal of Urological Surgery, 2022
Objective:The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC).Materials and Methods:Thirty patients with NMIBC and 30 age-matched ...
Oktay Üçer   +4 more
doaj   +1 more source

IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6 [PDF]

open access: yesThe Journal of Immunology, 2000
Abstract The genome of human herpes virus 8, which is associated with Kaposi’s sarcoma, encodes proteins with similarities to cytokines and chemokines including a homologue of IL-6. Although the function of these viral proteins is unclear, they might have the potential to modulate the immune system. For viral IL-6 (vIL-6), it has been
J, Müllberg   +9 more
openaire   +2 more sources

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