مجلة علوم ذي قار, 2023 The present study was carried out in the labs of Technical Institute –Al-Nasiriyah /Community Health Department and Nasiriyah Heart Center in Thi- Qar province, during the period of research was extended from January to July 2022 .
Taqwa Kadhem, Rasha Salih
doaj +1 more source
Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]
, 1998 Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Cremer, Peter +8 more
core +1 more source
Atherosclerosis Plus, 2023 Background and aims: Lipoprotein(a) [Lp(a)] and interleuking-6 (IL-6), an inflammation biomarker, have been established as distinct targets of the residual atherosclerotic cardiovascular disease (ASCVD) risk.
Anastasios Makris +6 more
doaj +1 more source
IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function. [PDF]
, 2019 Objective: We have previously shown that increased circulating interleukin-6 (IL-6) results in enhanced CD4+ T cell signaling via signal transduction and activator of transcription-3 (STAT3) in early rheumatoid arthritis (RA).
Aletaha +33 more
core +2 more sources
IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation
Frontiers in Immunology, 2022 Elevated levels and enhanced sensing of the pro-inflammatory cytokine interleukin-6 (IL-6) are key features of many autoimmune and inflammatory diseases.
Katharina Lambert +11 more
doaj +1 more source
Interleukin-6 (IL-6) Production by Astrocytes: Autocrine Regulation by IL-6 and the Soluble IL-6 Receptor [PDF]
The Journal of Neuroscience, 1999 In the CNS, astrocytes are a major inducible source of interleukin-6 (IL-6). Although IL-6 has beneficial effects in the CNS because of its neurotrophic properties, its overexpression is generally detrimental, adding to the pathophysiology associated with CNS disorders.
N J, Van Wagoner +3 more
openaire +2 more sources
The role of IL-6 and IL-6 blockade in COVID-19 [PDF]
Expert Review of Clinical Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a dysregulated hyperinflammatory response.Authors review evidence on IL-6 and IL-6 blockade in coronavirus disease 2019 (COVID-19) and discuss the pathophysiological and prognostic roles of this cytokine and the clinical impact of pharmacological blockade of IL-6 .
Nicola Potere +7 more
openaire +5 more sources
In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]
, 2019 An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D. +8 more
core +1 more source
The role of serum IL-6 changes in evaluation of endometriosis
مجلة كلية الطب, 2013 Background:- Endometriosis is a common chronic gynecological disorder characterized by the presence and proliferation of functional endometrial gland and stroma outside the uterine cavity, affecting approximately 10% of reproductive age women. Il-6 level
Tharwa H. Hassan AL-Tai +2 more
doaj +1 more source
Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients. [PDF]
, 2020 OBJECTIVE: To determine if there is correlation between intradiscal levels of interleukin-6 (IL-6) and early outcome measures in patients undergoing lumbar fusion for painful disc degeneration.
Anderson, D Greg +7 more
core +1 more source