Indonesian Journal of Chemistry, 2023 The objective of this study was to assess the predictive value of inflammatory biomarkers in COVID-19 patients, namely the CRP/albumin ratio (CAR), interleukin 6 (IL-6), IL-6/lymphocyte ratio (IL-6/LY), and neutrophil/lymphocyte ratio (NLR).
Agustin Iskandar +6 more
doaj +1 more source
Interleukin-6 mediates delirium-like phenotypes in a murine model of urinary tract infection
Journal of Neuroinflammation, 2021 Background Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay, and long-term cognitive decline. The pathogenesis
Mohammad Harun Rashid +8 more
doaj +1 more source
Evaluation of serum levels of interleukins 6, 8, 17 and 22 in acne vulgaris: A cross-sectional study
Indian Journal of Dermatology, 2023 Background: Acne vulgaris (AV) is a chronic, multifactorial, inflammatory skin disease, and it is now becoming increasingly clear that the inflammatory pathway is involved at a very early in the pathogenesis of acne.
Sweta Singh +2 more
doaj +1 more source
Serum IL–1β, IL–2, IL–6, and IL–8 levels in schizophrenia subtypes
Psychiatry and Clinical Psychopharmacology, 2021 Objective: The cytokines are considered to be an important topic in immunological studies of schizophrenia. In this clinical study IL-1β, IL-2, IL-6, and IL-8 levels were compared among schizophrenia subtypes and a control group.
Murat Kuloglu +4 more
doaj +1 more source
The Role of Interleukin-6, and IL-12+p40 in the Development of Ischemic Heart Disease
Kufa Journal for Nursing Sciences, 2023 Background: Because low-grade inflammation may play a role in the pathogenesis of coronary heart disease, and pro-inflammatory cytokines govern inflammatory cascades leading to atherosclerosis, and then to ischemic heart disease.
Dina A. A. Al-Roubaey +4 more
doaj +1 more source
Immunity, Inflammation and Disease, 2020 Introduction The aim of this study was to give quantitative insight into the number of cytokine molecules needed to activate a target cell and relate this to the physiological consequences of the amounts of cytokines typically detectable in humans.
Morten B. Hansen
doaj +1 more source
The immune and metabolic treatment approach of using testosterone on mice models of liver injury
Frontiers in Pharmacology, 2023 Background: Natural killer (NK) cells showed an anti-fibrotic effect; however, their function is thought to be impaired in advanced liver injury. In the current study, we aimed to assess the immune and metabolic impact of testosterone on mice models of ...
Johnny Amer +3 more
doaj +1 more source
Immunological studies of chronic ocular toxoplasmosis : up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6 [PDF]
, 2001 A murine model was used to characterize the local immune and inflammatory response during ocular toxoplasmosis. Major histocompatibility complex (MHC) class I, normally expressed at low levels in immune-privileged sites such as the eye, was up-regulated ...
Byrne, N. +6 more
core +4 more sources
IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]
, 2014 IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M. +5 more
core +1 more source
Molecules, 2021 The contemporary theory of the inflammatory-immunological pathomechanism of atherosclerosis includes the participation of interleukin-1β (Il), Il-6, Il-10, Il-12, RANTES, and homocysteine in this process.
Magdalena Borowska +5 more
doaj +1 more source