Results 41 to 50 of about 14,944,976 (275)

Carvacrol alleviates the proconvulsive effects of lipopolysaccharide (LPS) and reduces the gene expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-α [PDF]

Avicenna Journal of Phytomedicine
Objective: Carvacrol has anti-inflammatory effects. According to the links between inflammatory processes and seizures, this study was designed to investigate the potential effect of carvacrol in reducing seizure severity and involvement of hippocampal ...
Hesamodin Bagheripoor, Mahdieh Mondanizadeh, Mehdi Sadegh   +2 more
doaj   +1 more source

Interleukin (IL-6) Immunotherapy [PDF]

Cold Spring Harbor Perspectives in Biology, 2017
Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses.
Toshio, Tanaka, Masashi, Narazaki, Tadamitsu, Kishimoto   +2 more
openaire   +2 more sources

Validation of an automated enzyme immunoassay for interleukin-6 for routine clinical use [PDF]

, 1998
Serum levels of Interleukin-6 (IL-6), a proinflammatory cytokine, are increased in early stages of inflammatory diseases such as infection and sepsis. Assay systems which permit its measurement within a few hours and as a single measurement have not been
Peter Fraunberger, Michael Thein, Cremer, Peter, Peter Cremer, Dietrich Seidel, Isabelle Dehart, Seidel, Dietrich, Dorothea Nagel, Fraunberger, Peter, Dehart, Isabelle, Thein, Michael, Ernst Holler, Walli, Autar K., Autar K. Walli, Holler, Ernst, Pfeiffer, Matthias, Matthias Pfeiffer, Nagel, Dorothea   +17 more
core   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

Phenotypic and Functional Heterogeneity of Low-Density and High-Density Human Lung Macrophages

Biomedicines, 2021
Background: Pulmonary macrophages are a highly heterogeneous cell population distributed in different lung compartments. Methods: We separated two subpopulations of macrophages from human lung parenchyma according to flotation over density gradients ...
Barbara Balestrieri, Francescopaolo Granata, Stefania Loffredo, Angelica Petraroli, Giulia Scalia, Paolo Morabito, Chiara Cardamone, Gilda Varricchi, Massimo Triggiani   +8 more
doaj   +1 more source

IL-6 and diabetic kidney disease

Frontiers in Immunology
Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes associated with high mortality and disability rates. Inflammation has emerged as a key pathological mechanism in DKD, prompting interest in novel therapeutic approaches ...
Lei Zhang, Futian Xu, Liyan Hou
doaj   +1 more source

The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer

Journal of Urological Surgery, 2022
Objective:The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC).Materials and Methods:Thirty patients with NMIBC and 30 age-matched ...
Oktay Üçer, Gökhan Temeltaş, Talha Müezzinoğlu, Zeki Ari, Funda Kosova   +4 more
doaj   +1 more source

The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response [PDF]

, 2010
The aim of this article is to review current literature on the response of soluble interleukin-6 receptor to exercise and identify a potential role for sIL-6R in skeletal muscle function.
Stevenson, Emma, Nimmo, Myra, Cockburn, Emma, Stevenson, Emma J, Robson-Ansley, Paula, Walshe, Ian, Nimmo, Myra A   +6 more
core  

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis

Frontiers in Immunology, 2017
Paracoccidioidomycosis (PCM), a chronic granulomatous disease caused by the thermally dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii, has the highest mortality rate among systemic mycosis.
Fabrine Sales Massafera Tristão, Fernanda Agostini Rocha, Daniela Carlos, Natália Ketelut-Carneiro, Camila Oliveira Silva Souza, Cristiane Maria Milanezi, João Santana Silva   +6 more
doaj   +1 more source