Results 51 to 60 of about 2,245,474 (285)

The Effect of Transurethral Resection and BCG Therapy on Cytokine Levels in Non-Muscle Invasive Bladder Cancer

Journal of Urological Surgery, 2022
Objective:The present study investigated the effect of treatment on interleukin (IL)-1, IL-6, IL-8, and neopterin levels in patients with non-muscle invasive bladder cancer (NMIBC).Materials and Methods:Thirty patients with NMIBC and 30 age-matched ...
Oktay Üçer, Gökhan Temeltaş, Talha Müezzinoğlu, Zeki Ari, Funda Kosova   +4 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Producción de citoquinas proinflamatorias durante los estadios tempranos de la infección experimental por Paracoccidioides brasiliensis

Iatreia, 2001
La paracoccidioidomicosis (PCM) es una micosis sistémica restringida a América Latina y producida por la inhalación de las conidias del hongo dimórfico Paracoccidioides brasilienis (Pb) (1).
Luz Elena Cano, Angela Restrepo, Blanca Ortiz, Jorge Sahaza, Angel González   +4 more
doaj  

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Correlation Between Interleukin IL-6/IL-6 Receptor Polymorphisms (IL6–174C>G and IL6R 1073A>C) and RAS/BRAF Mutations in Patients with Colorectal Cancer

Gastroenterology Insights
Background: Chronic inflammation is an important factor in the development and progression of colorectal cancer (CRC). One of the key participants of chronic inflammation is interleukin-6 (IL-6), which enhances tumor malignancy.
Ekaterina Smagina, Dar’ya Polit’ko, Vadim Kumeiko, Lyudmila Gurina, Anna Stenkova   +4 more
doaj   +1 more source

The Role of gp130 Cytokines in Tuberculosis

Cells, 2020
Protective immune responses to Mycobacterium tuberculosis (Mtb) infection substantially depend on a delicate balance within cytokine networks. Thus, immunosuppressive therapy by cytokine blockers, as successfully used in the management of various chronic
Kristina Ritter, Jasmin Rousseau, Christoph Hölscher   +2 more
doaj   +1 more source

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
A Kitamura, AA Willette, AH Miller, AL Jefferson, AL Marsland, AL Sousa, American Psychiatric Association, Astrid V Rauch, AT Beck, B Balasubramaniam, B Viviani, Bernhard T Baune, BL Pierce, BT Baune, BT Baune, Carsten Konrad, CF Terry, Christina Uhlmann, CS Carlson, Dominik Grotegerd, E Brietzke, E Halperin, E Vermetten, Eva Birosova, F Faul, GM MacQueen, H Tilg, H-U Wittchen, Harald Kugel, I HapMap, I Hickie, I Morales, J Ashburner, J Hannestad, J McAfoose, J Oh, JA Wagner, JE Malberg, JM Gatt, JM Kim, Jochen Bauer, JP Godbout, K Kasai, K Pham, Katharina Domschke, KK Bowen, L Capuron, L Christiansen, L Vallieres, L Vitkovic, LD Ward, M Bonafe, M Murphy, M Pickering, M Yamada, MA Kahn, MA Munoz-Fernandez, MK Kang, ML Monje, MT Heneka, N Ohbayashi, N Pervaiz, N Raz, N Tzourio-Mazoyer, O Davidovich, O Islam, P Angelopoulos, P Oeth, P Videbech, Patricia Ohrmann, RA Gadient, RA Gadient, RM Thomas, S Campbell, S Eickhoff, S Ihara, S Ihara, S Lehrl, S Matsuda, S Toulmond, SA Loddick, SD Forman, Sonja Schöning, T Beblo, T Frodl, T Hama, T Hama, T Hirano, Thomas Suslow, U Dannlowski, Udo Dannlowski, V Tancredi, Volker Arolt, Walter Heindel, Y Akaneya, Y Dowlati, Y Kushima, Y Kushima, YP Peng, YY Wu   +99 more
core   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Environmental Circadian Disruption Elevates the IL-6 Response to Lipopolysaccharide in Blood [PDF]

, 2013
The immune system is regulated by circadian clocks within the brain and immune cells. Environmental circadian disruption (ECD), consisting of a 6-h phase advance of the light:dark cycle once a week for 4 weeks, elevates the inflammatory response to ...
Adams, Kandis L., Castanon-Cervantes, Oscar, Davidson, Alec J., Evans, Jennifer A.   +3 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source