Results 71 to 80 of about 14,944,976 (275)
IL-6 and IL-18 cytokine traps in COVID-19
Инфекция и иммунитетCytokines are mediators of immunity that regulate inflammation. Intensity of inflammatory process is strongly dependent on the cytokine type and duration of its effect.
A. A. Korotaeva +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens +6 more
wiley +1 more source
The Role of gp130 Cytokines in Tuberculosis
Cells, 2020 Protective immune responses to Mycobacterium tuberculosis (Mtb) infection substantially depend on a delicate balance within cytokine networks. Thus, immunosuppressive therapy by cytokine blockers, as successfully used in the management of various chronic
Kristina Ritter +2 more
doaj +1 more source
IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6 [PDF]
The Journal of Immunology, 2000 Abstract The genome of human herpes virus 8, which is associated with Kaposi’s sarcoma, encodes proteins with similarities to cytokines and chemokines including a homologue of IL-6. Although the function of these viral proteins is unclear, they might have the potential to modulate the immune system. For viral IL-6 (vIL-6), it has been
J, Müllberg +9 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho +6 more
wiley +1 more source
IL-6-STAT3 signaling is over-activated in osteoporotic BMSCs.
, 2016 The expression of thirty-six important bone metabolism markers was measured in normal and osteoporotic BMSCs treated with BMP2 for 7 days using an antibody array (A).
Xiang Li (114679) +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Physical rehabilitation is highly recognised in improving the quality of life of cancer survivors through prehabilitation, sequelae management and palliative care, yet its integration into routine care in Ghana has not been characterised, leading to potential gaps in service access.
Dorothy Ekua Adjabu +5 more
wiley +1 more source
Effects of IL-6 and IL-6 blockade on neutrophil function in vitro and in vivo [PDF]
Rheumatology, 2014 Reports on the regulation of neutrophil function by IL-6 are often conflicting. Therapeutic inhibition of IL-6 in RA is associated with occasional neutropenia, but the mechanisms underlying this observation are poorly understood. This study investigated interactions between IL-6, the anti-IL-6 receptor agent tocilizumab (TCZ) and neutrophils in vitro ...
Helen L, Wright +3 more
openaire +2 more sources
, 2022 Expression of IL-6 in negative control group of HepG2 cells by immunocytochemistry (400x magnification)
Ricadonna Raissa (12081878)
core +1 more source
Spotlight on tocilizumab and its potential in the treatment of systemic sclerosis
Drug Design, Development and Therapy, 2016 Lazaros I Sakkas Department of Rheumatology and Clinical Immunology, Medical School, University of Thessaly, Larissa, Greece Abstract: Systemic sclerosis (SSc) is a multisystem disease characterized by extensive collagen deposition in skin and internal
Sakkas LI
doaj