Results 1 to 10 of about 63,742,190 (280)

IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 Biology [PDF]

open access: yesFrontiers in Immunology, 2021
Cytokines are powerful mediators of inflammation. Consequently, their potency is regulated in many ways to protect the host. Several cytokines, including IL-22, have coordinating binding proteins or soluble receptors that bind to the cytokine, block the ...
Lauren A. Zenewicz
doaj   +3 more sources

Microbiota-Dependent Effects of IL-22 [PDF]

open access: yesCells, 2020
Cytokines are important contributors to immune responses against microbial and environmental threats and are of particular importance at epithelial barriers. These interfaces are continuously exposed to external factors and thus require immune components
Morsal Sabihi   +3 more
doaj   +3 more sources

Evaluation of serum levels of interleukins 6, 8, 17 and 22 in acne vulgaris: A cross-sectional study

open access: yesIndian Journal of Dermatology, 2023
Background: Acne vulgaris (AV) is a chronic, multifactorial, inflammatory skin disease, and it is now becoming increasingly clear that the inflammatory pathway is involved at a very early in the pathogenesis of acne.
Sweta Singh   +2 more
doaj   +1 more source

IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix

open access: yesFrontiers in Immunology, 2022
The uterine endometrium uniquely regenerates after menses, postpartum, or after breaks in the uterine layer integrity throughout women’s lives. Direct cell–cell contacts ensured by tight and adherens junctions play an important role in endometrial ...
Umida Ganieva   +6 more
doaj   +1 more source

The effect of high-intensity interval training on IL-22 and STAT3 gene expression of liver tissue in steatosis animal model [PDF]

open access: yesJournal of Exercise & Organ Cross Talk, 2023
Inflammation is a major component of almost all acute and chronic liver disorders, including non-alcoholic fatty liver disease. This study aimed to investigate the effect of high-intensity interval training on IL-22 and STAT3 gene expression of liver ...
Vahideh Ebrahimi Gharab   +3 more
doaj   +1 more source

Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2023
Background This study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-inflammatory and anti-inflammatory cytokines) in 90 patients with mild/moderate coronavirus disease 2019 (COVID-19) and 90 healthy controls.
Abdulraheem Y. Majeed   +2 more
doaj   +1 more source

IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice

open access: yesArthritis Research & Therapy, 2022
Background Interstitial lung disease, a common extra-articular complication of connective tissue disease, is characterized by progressive and irreversible pulmonary inflammation and fibrosis, which causes significant mortality. IL-22 shows a potential in
Ziye Qu   +5 more
doaj   +1 more source

Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/IκBα pathway

open access: yesArthritis Research & Therapy, 2020
Background The present study aimed to evaluate the suppressive role of interleukin (IL)-25 in IL-22-induced osteoclastogenesis and receptor activator of nuclear factor κB ligand (RANKL) expression in rheumatoid arthritis (RA). Methods Serum from patients
Hong Ki Min   +7 more
doaj   +1 more source

CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

open access: yesOncoImmunology, 2023
Metastasis is a cancer-related systemic disease and is responsible for the greatest mortality rate among cancer patients. Interestingly, the interaction between the immune system and cancer cells seems to play a key role in metastasis formation in the ...
Tao Zhang   +51 more
doaj   +1 more source

Significance of Interleukin-22 and CD38 in Chronic Lymphocytic Leukemia [PDF]

open access: yesMinia Journal of Medical Research, 2019
Chronic lymphocytic leukaemia (CLL) is a common type of leukaemia characterised by an abnormal increase in T-cell count. T-helper cytokines were reported to stimulate the survival and proliferation of CLL cells and could be correlated with disease ...
Nancy Youssef   +3 more
doaj   +1 more source

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