IL-22 in Atopic Dermatitis [PDF]
CellsAtopic dermatitis (AD) is a prevalent and chronic inflammatory skin condition characterized by a multifaceted pathophysiology that gives rise to diverse clinical manifestations.
Julia Laska +4 more
doaj +4 more sources
A Critical Role of the IL-22–IL-22 Binding Protein Axis in Hepatocellular Carcinoma [PDF]
Cancers, 2022 Hepatocellular carcinoma (HCC) ranks among the five most common cancer entities worldwide and leads to hundred-thousands of deaths every year. Despite some groundbreaking therapeutical revelations during the last years, the overall prognosis remains poor.
Anastasios D. Giannou +39 more
core +8 more sources
Decidual Interleukin-22-Producing CD4+ T Cells (Th17/Th0/IL-22+ and Th17/Th2/IL-22+, Th2/IL-22+, Th0/IL-22+), Which Also Produce IL-4, Are Involved in the Success of Pregnancy [PDF]
International Journal of Molecular Sciences, 2019 Trophoblast expressing paternal HLA-C resembles a semiallograft, and could be rejected by maternal T cells. IL-22 seems to be involved in allograft rejection and thus could be responsible for miscarriages. We examined the role of decidual IL-22-producing CD4+ T on human pregnancy.
Logiodice F. +6 more
openaire +8 more sources
Characterization of IL-22 Bioactivity and IL-22-Positive Cells in Grass Carp Ctenopharyngodon idella [PDF]
Frontiers in Immunology, 2020 Interleukin (IL)-22 plays an important role in regulating inflammation and clearance of infectious pathogens. IL-22 homologs have been discovered in fish, but the functions and sources of IL-22 have not been fully characterized.
Yibin Yang +27 more
doaj +3 more sources
Serum Levels of IL-22 and ACPA in Patients with Rheumatoid Arthritis
Journal of Pure and Applied Microbiology, 2018 Both rheumatoid arthritis and periodontitis are complex multifactorial disorders, characterized not only by a dysfunction of basic inflammatory and tissue destructive mechanisms, but also by an altered adaptive and innate immune response in individuals ...
Zainab A. Aldhaher +2 more
doaj +2 more sources
FEBS Letters, 2008 MINT‐6693956: Il22 (uniprotkb:Q9GZX6) and IL22R1 (uniprotkb:Q8N6P7) bind (MI:0407) by X-ray crystallography (MI:0114)
Bleicher, Lucas +6 more
openaire +3 more sources
The AhR/IL-22 axis in chronic gut inflammation: unraveling mechanisms and therapeutic prospects [PDF]
Frontiers in ImmunologyChronic inflammatory bowel diseases, including Crohn’s disease (CD), ulcerative colitis (UC), and post-infectious irritable bowel syndrome (PI-IBS), are characterized by immune-mediated intestinal inflammation and epithelial barrier dysfunction. Research
Huimin Kang +4 more
doaj +2 more sources
Serum Levels of IL-21 and IL-22 in Breast Cancer Patients—A Preliminary Study [PDF]
Current Issues in Molecular BiologyBreast cancer is one of the most commonly diagnosed malignant tumours in women worldwide. Although modern medicine has led to advanced diagnostic methods and therapies that allow for increasingly effective treatment, the mechanisms underlying breast ...
Jacek Kabut +8 more
doaj +2 more sources
ES-62 protects against collagen-induced arthritis by resetting interleukin-22 towards resolution of inflammation in the joints [PDF]
, 2014 Objective. The parasitic worm–derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17 associated cytokine
Al-Riyami, Lamyaa +4 more
core +3 more sources
IL‐22 in antifungal immunity [PDF]
European Journal of Immunology, 2011 AbstractDeciphering cellular and molecular mechanisms that maintain host immune homeostasis with fungi and the breakdown of this homeostatic tolerance during fungal infections disease is a challenge in medical mycology. In fact, the virulence of fungi may be determined by the interaction between fungi and the host immune status and its classification ...
ZELANTE, TERESA +3 more
openaire +3 more sources