Results 11 to 20 of about 1,381,565 (235)

The effect of high-intensity interval training on IL-22 and STAT3 gene expression of liver tissue in steatosis animal model [PDF]

open access: yesJournal of Exercise & Organ Cross Talk, 2023
Inflammation is a major component of almost all acute and chronic liver disorders, including non-alcoholic fatty liver disease. This study aimed to investigate the effect of high-intensity interval training on IL-22 and STAT3 gene expression of liver ...
Vahideh Ebrahimi Gharab   +3 more
doaj   +1 more source

IL-22 regulates endometrial regeneration by enhancing tight junctions and orchestrating extracellular matrix

open access: yesFrontiers in Immunology, 2022
The uterine endometrium uniquely regenerates after menses, postpartum, or after breaks in the uterine layer integrity throughout women’s lives. Direct cell–cell contacts ensured by tight and adherens junctions play an important role in endometrial ...
Umida Ganieva   +6 more
doaj   +1 more source

IL‐22 in antifungal immunity [PDF]

open access: yesEuropean Journal of Immunology, 2011
AbstractDeciphering cellular and molecular mechanisms that maintain host immune homeostasis with fungi and the breakdown of this homeostatic tolerance during fungal infections disease is a challenge in medical mycology. In fact, the virulence of fungi may be determined by the interaction between fungi and the host immune status and its classification ...
ZELANTE, TERESA   +3 more
openaire   +3 more sources

Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2023
Background This study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-inflammatory and anti-inflammatory cytokines) in 90 patients with mild/moderate coronavirus disease 2019 (COVID-19) and 90 healthy controls.
Abdulraheem Y. Majeed   +2 more
doaj   +1 more source

A Critical Role of the IL-22–IL-22 Binding Protein Axis in Hepatocellular Carcinoma

open access: yesCancers, 2022
Hepatocellular carcinoma (HCC) ranks among the five most common cancer entities worldwide and leads to hundred-thousands of deaths every year. Despite some groundbreaking therapeutical revelations during the last years, the overall prognosis remains poor.
Anastasios D. Giannou   +39 more
openaire   +4 more sources

IL-22 in mucosal immunity [PDF]

open access: yesMucosal Immunology, 2008
Recent studies in infectious disease and autoimmune disease models have revealed that interleukin (IL)-22 might have both proinflammatory and anti-inflammatory functions. There is, however, lack of evidence for IL-22 directly repressing immune responses of leukocytes.
W, Ouyang, P, Valdez
openaire   +2 more sources

IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice

open access: yesArthritis Research & Therapy, 2022
Background Interstitial lung disease, a common extra-articular complication of connective tissue disease, is characterized by progressive and irreversible pulmonary inflammation and fibrosis, which causes significant mortality. IL-22 shows a potential in
Ziye Qu   +5 more
doaj   +1 more source

Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/IκBα pathway

open access: yesArthritis Research & Therapy, 2020
Background The present study aimed to evaluate the suppressive role of interleukin (IL)-25 in IL-22-induced osteoclastogenesis and receptor activator of nuclear factor κB ligand (RANKL) expression in rheumatoid arthritis (RA). Methods Serum from patients
Hong Ki Min   +7 more
doaj   +1 more source

CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

open access: yesOncoImmunology, 2023
Metastasis is a cancer-related systemic disease and is responsible for the greatest mortality rate among cancer patients. Interestingly, the interaction between the immune system and cancer cells seems to play a key role in metastasis formation in the ...
Tao Zhang   +51 more
doaj   +1 more source

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