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2.2. Il nulla nulleggia ancora
Rivista di Estetica, 2012 Carnap (1932) famously attacked Heidegger for having constructed an insane metaphysics based on a misconception of both the logical form and the semantics of ordinary language.
Alberto Voltolini
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Group 3 Innate Lymphoid Cells Protect Steatohepatitis From High-Fat Diet Induced Toxicity
Frontiers in Immunology, 2021 Background and Aims: Emerging evidence has revealed that innate lymphoid cells (ILCs) play a key role in regulating metabolic disorders. Here, we investigated the role of group 3 ILCs (ILC3s) in the modulation of Non-alcoholic fatty liver disease (NAFLD).
Masahide Hamaguchi +13 more
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Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
Exploration of Immunology, 2021 Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
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Recent advances in IL-22 biology [PDF]
International Immunology, 2011 Several cell types, in particular epithelial cells, express the receptor for the cytokine IL-22 and upon its recognition produce molecules that are active both locally and systemically. Many different types of lymphocyte secrete IL-22. T(h)17 cells produce IL-22 although the optimal conditions for secretion of IL-17 or IL-22 by T(h)17 cells differ, as ...
Lauren A, Zenewicz, Richard A, Flavell
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IL-22 and IL-22 receptor expression after MI and sham.
, 2023 Serum levels of IL-22 at the indicated time points before and after MI (A) and sham(B) were determined by microbeads-based assay (n = 3 to 8 for each group).
Mai Yamamoto (3205116) +10 more
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Investigating IL-22 gene polymorphism in patients afflicted with inflammatory bowel disease [PDF]
Journal of Advanced Biomedical Sciences, 2017 Background & Objective: inflammatory bowel disease is related to a group of chronic inflammatory disorders with unknown etiology which involves the digestive system.
Ali Moravej +5 more
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The Interleukin-10 Family of Cytokines and Their Role in the CNS
Frontiers in Cellular Neuroscience, 2018 Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R. Burmeister, Ian Marriott
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Role of IL‐22 in homeostasis and diseases of the skin
APMIS, 2022 Interleukin‐22 (IL‐22) is a cytokine mainly produced by T cells and innate lymphoid cells (ILC). IL‐22 primarily targets non‐hematopoietic cells such as epithelial cells and fibroblasts. In the skin, IL‐22 promotes the proliferation of keratinocytes and dermal fibroblasts. IL‐22 furthermore regulates innate immune responses as it induces the production
Lopez, Daniel Villalba +1 more
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, 2017 There remain significant obstacles in developing biologics to treat primary biliary cholangitis (PBC). Although a number of agents have been studied both in murine models and human patients, the results have been relatively disappointing.
莊雅惠 +1 more
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IL-22: There Is a Gap in Our Knowledge [PDF]
ImmunoHorizons, 2018 Abstract IL-22 is a critical cytokine in modulating tissue responses during inflammation. IL-22 is upregulated in many chronic inflammatory diseases, making IL-22 biology a potentially rewarding therapeutic target. However, this is complicated by the dual-natured role of IL-22 in inflammation, as the cytokine can be protective or ...
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