Effect of Aerobic Training with Aqueous Allium sativum L on IL-17, IL-22 Expression and Insulin Resistance in Diabetic Rats [PDF]
Background and Purpose: There is now mounting evidence that pro-inflammatory pathways, which are mediated by T cells (that secrete IL-17 and IL-22), play a critical role in metabolic control.
Elnaz Sadeghpour Firozabadi +2 more
doaj +1 more source
IL-22-Fc promotes wound healing in db/db mice. [PDF]
(A) Wound gaps of a clean wound on the back of db/db and lean control mice (n = 7). (B-F) db/db mice with wounds i.p. injected with control Fc, IL-22-Fc or anti-FGFR1 (n = 7). (B) Wound gaps.
Jason A. Hackney (29921) +9 more
core +1 more source
Group 3 Innate Lymphoid Cells Protect Steatohepatitis From High-Fat Diet Induced Toxicity
Background and Aims: Emerging evidence has revealed that innate lymphoid cells (ILCs) play a key role in regulating metabolic disorders. Here, we investigated the role of group 3 ILCs (ILC3s) in the modulation of Non-alcoholic fatty liver disease (NAFLD).
Masahide Hamaguchi +13 more
doaj +1 more source
IL-22-Fc induced genes involved in wound healing. [PDF]
Skins were harvested on day 7 after treatment with control Fc, IL-22-Fc, PDGF or VEGF (n = 3–5). Microarray analysis was done with purified skin RNA. (A) Heat map of genes that were differentially regulated with treatments.
Jason A. Hackney (29921) +9 more
core +1 more source
Significance of Interleukin-22 and CD38 in Chronic Lymphocytic Leukemia [PDF]
Chronic lymphocytic leukaemia (CLL) is a common type of leukaemia characterised by an abnormal increase in T-cell count. T-helper cytokines were reported to stimulate the survival and proliferation of CLL cells and could be correlated with disease ...
Nancy Youssef +3 more
doaj +1 more source
IL-22-Fc treatment is superior to VEGF and PDGF in S. aureus infected diabetic wounds. [PDF]
(A-B) C57BL/6 mice were i.p. injected with control or IL-22-Fc (n = 6), shaved skins on the back were harvested in 24 hours. mRNA expression of s100a9 (A), and Defb1 (B). (C) Wound closure of wounds infected with control (n = 8) or with S.aureus (n = 9).
Jason A. Hackney (29921) +9 more
core +1 more source
Data_Sheet_1_Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk.docx [PDF]
Vulvovaginal candidiasis (VVC) is a common mucosal infection caused by Candida spp., most frequently by Candida albicans, which may become recurrent and severely impacting the quality of life of susceptible women.
Monica Borghi (198897) +12 more
core +1 more source
Serum Levels of IL-10 and IL-22 Cytokines in Patients with Psoriasis [PDF]
Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (
Mohammad Reza Sobhan +4 more
doaj
Innate lymphoid cells type 3 in cancer
Cancer is a multifactorial chronic illness caused by a combination of genetic and environmental factors. A tumor is more than just a collection of cancer cells, it also contains infiltrating and resident host cells that are constantly interacting with it.
Raquel Castillo-González +5 more
doaj +1 more source
IL-22-mediated signaling enhances the gene expression of anti-apoptotic and antimicrobial proteins in lung epithelial cells. [PDF]
One month after the induction of diabetes, T2DM mice were infected with 50–100 CFU of aerosolized Mtb. The mice were then treated intravenously with either recombinant IL-22 (100 ng/kg body weight, twice weekly, starting 5 months p.i.) or PBS.
Rajesh Kumar Radhakrishnan (5587778) +9 more
core +1 more source

