Results 31 to 40 of about 1,381,565 (235)
IL-22 Fate Reporter Reveals Origin and Control of IL-22 Production in Homeostasis and Infection [PDF]
The Journal of Immunology, 2014 Abstract IL-22 is a cytokine that regulates tissue homeostasis at barrier surfaces. A variety of IL-22–producing cell types is known, but identification on the single-cell level remains difficult. Therefore, we generated a fate reporter mouse that would allow the identification of IL-22–producing cells and their fate mapping in vivo.
Ahlfors, Helena +8 more
openaire +3 more sources
The Interleukin-10 Family of Cytokines and Their Role in the CNS
Frontiers in Cellular Neuroscience, 2018 Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R. Burmeister, Ian Marriott
doaj +1 more source
Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis
Acta Dermato-Venereologica, 2017 Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these ...
Kazuhisa Furue +8 more
doaj +1 more source
Colonizing Microbes, IL-10 and IL-22: Keeping the Peace at the Mucosal Surface
Frontiers in Microbiology, 2021 Our world is filled with microbes. Each multicellular organism has developed ways to interact with this microbial environment. Microbes do not always pose a threat; they can contribute to many processes that benefit the host.
Evelien Kidess +2 more
doaj +1 more source
Effects of all-trans retinoic acid on the function of Cx43 and GJIC in HaCaT cells induced by IL-22
Pifu-xingbing zhenliaoxue zazhi, 2019 Objective: To investigate the effect of all-trans retinoic acid (ATRA) on Cx43 protein expression and GJIC function in IL-22-treated HaCaT cells, and whether it is related to the JNK pathway to further elaborate molecular mechanism of ATRA on GJIC ...
Xiao-dong LIANG +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi +20 more
wiley +1 more source
The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy
Respiratory ResearchPleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung structure damage and the development of various respiratory issues.
Qian Niu, Meng Wang, Xian-Sheng Liu
doaj +1 more source
IL-22: There Is a Gap in Our Knowledge [PDF]
ImmunoHorizons, 2018 Abstract IL-22 is a critical cytokine in modulating tissue responses during inflammation. IL-22 is upregulated in many chronic inflammatory diseases, making IL-22 biology a potentially rewarding therapeutic target. However, this is complicated by the dual-natured role of IL-22 in inflammation, as the cytokine can be protective or ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges +12 more
wiley +1 more source
Clinical and Experimental Obstetrics & Gynecology, 2023 Objectives: Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disease characterized by thrombocytopenia. This review will examine the Notch-aromatic hydrocarbon receptor (AhR)-interleukin-22 (IL-22) signaling pathway regulatory mechanisms ...
Qian-qian Fan, Rong-xia He
doaj +1 more source