Results 41 to 50 of about 63,742,190 (280)

IL-22 Fate Reporter Reveals Origin and Control of IL-22 Production in Homeostasis and Infection [PDF]

The Journal of Immunology, 2014
Abstract IL-22 is a cytokine that regulates tissue homeostasis at barrier surfaces. A variety of IL-22–producing cell types is known, but identification on the single-cell level remains difficult. Therefore, we generated a fate reporter mouse that would allow the identification of IL-22–producing cells and their fate mapping in vivo.
Ahlfors, Helena, Morrison, Peter J, Duarte, Joao H, Li, Ying, Biro, July, Tolaini, Mauro, Di Meglio, Paola, Potocnik, Alexander J, Stockinger, Brigitta   +8 more
openaire   +3 more sources

Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis

Acta Dermato-Venereologica, 2017
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these ...
Kazuhisa Furue, Kazuhiko Yamamura, Gaku Tsuji, Chikage Mitoma, Hiroshi Uchi, Takeshi Nakahara, Makiko Kido-Nakahara, Takafumi Kadono, Masutaka Furue   +8 more
doaj   +1 more source

Effects of all-trans retinoic acid on the function of Cx43 and GJIC in HaCaT cells induced by IL-22

Pifu-xingbing zhenliaoxue zazhi, 2019
Objective: To investigate the effect of all-trans retinoic acid (ATRA) on Cx43 protein expression and GJIC function in IL-22-treated HaCaT cells, and whether it is related to the JNK pathway to further elaborate molecular mechanism of ATRA on GJIC ...
Xiao-dong LIANG, Jie DENG, Rui-xian YE, Huan-yan LIU, Qi-ying XIONG, Ru-jun XUE, Hui-heng CHEN, Yu-mei LIU, Jing-yao LIANG, Xi-bao ZHANG   +9 more
doaj   +1 more source

Healing of intestinal inflammation by IL-22 [PDF]

Inflammatory Bowel Diseases, 2012
An interleukin (IL)-10 family cytokine, IL-22 is characterized by several unique biological properties, including 1) the target restricted to innate cells; 2) the distinct expression pattern between large and small intestines; 3) alteration of the cellular source depending on several factors; 4) the dual abilities to serve as protective versus ...
openaire   +2 more sources

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy

Respiratory Research
Pleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung structure damage and the development of various respiratory issues.
Qian Niu, Meng Wang, Xian-Sheng Liu
doaj   +1 more source

Serum Interleukin-22 as a Marker of Decompensated Liver Cirrhosis and Hepatocellular Carcinoma in Chronic Hepatitis C Virus Patients [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim: Chronic liver disease (CLD), when associated with chronic hepatitis C virus (HCV) infection, typically develops into cirrhosis and hepatocellular carcinoma (HCC).
Rania Abou Youssef, Ayman Elshayeb, Akram Deghady, Noura Hosny   +3 more
doaj   +1 more source

Immunobiology of IL-17A in human colorectal cancer [PDF]

, 2015
During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
core   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source