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2.2. Il nulla nulleggia ancora
Carnap (1932) famously attacked Heidegger for having constructed an insane metaphysics based on a misconception of both the logical form and the semantics of ordinary language.
Alberto Voltolini
doaj +1 more source
Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
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IL-22 regulates genes involved in intestinal immune defence responses. [PDF]
WT organoids were treated with IL-22 (2 ng/ml) for 3 hours. RNA was isolated for RNAseq analysis. (A) Volcano plot showing fold change (log2) in gene expression of WT organoids treated with IL-22 (2 ng/ml) for 3 hours compared to untreated WT organoids ...
Yu Chen (29959) +5 more
core +1 more source
Investigating IL-22 gene polymorphism in patients afflicted with inflammatory bowel disease [PDF]
Background & Objective: inflammatory bowel disease is related to a group of chronic inflammatory disorders with unknown etiology which involves the digestive system.
Ali Moravej +5 more
doaj
IL-22 serum levels in patients with uveitis. [PDF]
Serum was obtained from patients with uveitis (n = 20) and healthy donors (n = 19). It was separated from whole blood using a serum-separating tube by centrifuging at 600 x g for 10 min.
Tae Wan Kim (140536) +10 more
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IL-22 Fate Reporter Reveals Origin and Control of IL-22 Production in Homeostasis and Infection [PDF]
Abstract IL-22 is a cytokine that regulates tissue homeostasis at barrier surfaces. A variety of IL-22–producing cell types is known, but identification on the single-cell level remains difficult. Therefore, we generated a fate reporter mouse that would allow the identification of IL-22–producing cells and their fate mapping in vivo.
Ahlfors, Helena +8 more
openaire +3 more sources
Role of IL‐22 in homeostasis and diseases of the skin
Interleukin‐22 (IL‐22) is a cytokine mainly produced by T cells and innate lymphoid cells (ILC). IL‐22 primarily targets non‐hematopoietic cells such as epithelial cells and fibroblasts. In the skin, IL‐22 promotes the proliferation of keratinocytes and dermal fibroblasts. IL‐22 furthermore regulates innate immune responses as it induces the production
Lopez, Daniel Villalba +1 more
openaire +4 more sources
IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice [PDF]
Diabetic foot ulcers (DFU) are one of the major complications in type II diabetes patients and can result in amputation and morbidity. Although multiple approaches are used clinically to help wound closure, many patients still lack adequate treatment ...
Jason A Hackney +19 more
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Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these ...
Kazuhisa Furue +8 more
doaj +1 more source
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +1 more source

