Results 51 to 60 of about 6,541,017 (281)
The Interleukin-10 Family of Cytokines and Their Role in the CNS
Frontiers in Cellular Neuroscience, 2018 Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R. Burmeister, Ian Marriott
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Healing of intestinal inflammation by IL-22 [PDF]
Inflammatory Bowel Diseases, 2012 An interleukin (IL)-10 family cytokine, IL-22 is characterized by several unique biological properties, including 1) the target restricted to innate cells; 2) the distinct expression pattern between large and small intestines; 3) alteration of the cellular source depending on several factors; 4) the dual abilities to serve as protective versus ...
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Identification of Reg3β-producing cells using IL-22-stimulated enteroids [PDF]
, 2019 Reg3β, a lectin, displays antibacterial activity. This study investigated Reg3β-expressing cells using IL-22-stimulated enteroids. IL-22 stimulation elevated the mRNA and protein levels of Reg3β.
Yuki Saito (230959) +6 more
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Effects of all-trans retinoic acid on the function of Cx43 and GJIC in HaCaT cells induced by IL-22
Pifu-xingbing zhenliaoxue zazhi, 2019 Objective: To investigate the effect of all-trans retinoic acid (ATRA) on Cx43 protein expression and GJIC function in IL-22-treated HaCaT cells, and whether it is related to the JNK pathway to further elaborate molecular mechanism of ATRA on GJIC ...
Xiao-dong LIANG +9 more
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Clinical and Experimental Obstetrics & Gynecology, 2023 Objectives: Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disease characterized by thrombocytopenia. This review will examine the Notch-aromatic hydrocarbon receptor (AhR)-interleukin-22 (IL-22) signaling pathway regulatory mechanisms ...
Qian-qian Fan, Rong-xia He
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley +1 more source
Immunobiology of IL-17A in human colorectal cancer [PDF]
, 2015 During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
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The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy
Respiratory ResearchPleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung structure damage and the development of various respiratory issues.
Qian Niu, Meng Wang, Xian-Sheng Liu
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IL-22: There Is a Gap in Our Knowledge [PDF]
ImmunoHorizons, 2018 Abstract IL-22 is a critical cytokine in modulating tissue responses during inflammation. IL-22 is upregulated in many chronic inflammatory diseases, making IL-22 biology a potentially rewarding therapeutic target. However, this is complicated by the dual-natured role of IL-22 in inflammation, as the cytokine can be protective or ...
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IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response. [PDF]
, 2020 Cytokines maintain intestinal health, but precise intercellular communication networks remain poorly understood. Macrophages are immune sentinels of the intestinal tissue and are critical for gut homeostasis.
Louise Chappell-Maor (2559871) +13 more
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