Results 51 to 60 of about 63,742,190 (280)

IL-22-Fc promotes wound healing in db/db mice.

, 2017
(A) Wound gaps of a clean wound on the back of db/db and lean control mice (n = 7). (B-F) db/db mice with wounds i.p. injected with control Fc, IL-22-Fc or anti-FGFR1 (n = 7). (B) Wound gaps.
Jason A. Hackney (29921), Vineela Gandham (3709540), Xiumin Wu (3709537), Wyne P. Lee (3709543), Dimitry M. Danilenko (3709546), Jose Zavala-Solorio (381386), Puneet Arora (3709534), Xiaoting Wang (206653), Wenjun Ouyang (1533880), Ganesh Kolumam (178774)   +9 more
core   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

IL-22-Fc induced genes involved in wound healing.

, 2017
Skins were harvested on day 7 after treatment with control Fc, IL-22-Fc, PDGF or VEGF (n = 3–5). Microarray analysis was done with purified skin RNA. (A) Heat map of genes that were differentially regulated with treatments.
Jason A. Hackney (29921), Vineela Gandham (3709540), Xiumin Wu (3709537), Wyne P. Lee (3709543), Dimitry M. Danilenko (3709546), Jose Zavala-Solorio (381386), Puneet Arora (3709534), Xiaoting Wang (206653), Wenjun Ouyang (1533880), Ganesh Kolumam (178774)   +9 more
core   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

CircRAB3B suppresses proliferation, motility, cell cycle progression and promotes the apoptosis of IL-22-induced keratinocytes depending on the regulation of miR-1228-3p/PTEN axis in psoriasis

Autoimmunity, 2021
Introduction Psoriasis is an immune-related chronic skin disease, and interleukin-22 (IL-22) is involved in psoriasis pathogenesis through promoting proliferation and migration abilities of keratinocytes.
Jiajing Lu, Xin Xu, Ying Li, Ning Yu, Yangfeng Ding, Yuling Shi   +5 more
doaj   +1 more source

IL-22-Fc treatment is superior to VEGF and PDGF in S. aureus infected diabetic wounds.

, 2017
(A-B) C57BL/6 mice were i.p. injected with control or IL-22-Fc (n = 6), shaved skins on the back were harvested in 24 hours. mRNA expression of s100a9 (A), and Defb1 (B). (C) Wound closure of wounds infected with control (n = 8) or with S.aureus (n = 9).
Jason A. Hackney (29921), Vineela Gandham (3709540), Xiumin Wu (3709537), Wyne P. Lee (3709543), Dimitry M. Danilenko (3709546), Jose Zavala-Solorio (381386), Puneet Arora (3709534), Xiaoting Wang (206653), Wenjun Ouyang (1533880), Ganesh Kolumam (178774)   +9 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

ILC3 Function as a Double-Edged Sword in EV71 Infection

Viruses
Enterovirus 71 (EV71) is a common pathogen responsible for hand, foot, and mouth disease (HFMD), leading to severe neurological complications and even death.
Chang Zhang, Linlin Bao, Feifei Qi, Qi Lv, Fengdi Li, Chuan Qin   +5 more
doaj   +1 more source

Data_Sheet_1_Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk.docx

, 2019
Vulvovaginal candidiasis (VVC) is a common mucosal infection caused by Candida spp., most frequently by Candida albicans, which may become recurrent and severely impacting the quality of life of susceptible women.
Monica Borghi (198897), Marina M. Bellet (7488542), Giorgia Renga (655372), Luigina Romani (195694), Marilena Pariano (6669215), Claudia Stincardini (4336312), Matteo Puccetti (655374), Stefano Brancorsini (3809080), Claudio Costantini (6016601), Carmine Vacca (6669221), Valentina Solito (7488539), Paolo Mosci (347203), Federica Sellitto (7488545)   +12 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source