In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines [PDF]
, 2002 We show that a combination of the immunosuppressive drugs, vitamin D3 and Dexamethasone, induced human and mouse naive CD4(+) T cells to differentiate in vitro into regulatory T cells.
Hawrylowicz, C.M. +39 more
core +1 more source
Journal of Neuroinflammation, 2019 Background Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague.
Yi Sun +9 more
doaj +1 more source
IL-10-producing Breg subsets in HIV+ patients and healthy individuals. [PDF]
, 2019 PBMCs were isolated, and some cells were stimulated with CD40L/LPS/CpG. After 2 days, cells were labeled for surface markers and intracellular IL-10.
Verónica Pérez-Fernández (6519359) +7 more
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GENERATION OF IL-17 IMMUNE RESPONSE IN OBESE PATIENTS WITH ASTHMA
Наука и инновации в медицине, 2017 Aim - to investigate the influence of IL-17, IL-10 on the level of asthma control among obese patients. Materials and methods. 79 patients with asthma aged from 18 to 65 years were enrolled in our study and categorized into three groups according to ...
MS S Nurdina, VI I Kupaev, OV V Sazonova
doaj +1 more source
Pseudaminic acid on Campylobacter jejuni flagella modulates dendritic cell IL-10 expression via Siglec-10 receptor: a novel flagellin-host interaction. [PDF]
, 2014 INTRODUCTION: Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. At present the identity of host-pathogen interactions that promote successful bacterial colonisation remain ill defined.
Crocker, Paul R. +13 more
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Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]
, 2012 Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem +23 more
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Association between human IL-10 gene polymorphisms and serum IL-10 level in patients with food allergy [PDF]
, 2014 Background/Purpose: Single nucleotide polymorphisms (SNPs) of the interleukin-10 (IL-10) gene are associated with allergic diseases in different populations.
Chen, Tuo-Kang;Lee, Jyh-Hong;Yu, Hsin-Hui;Yang, Yao-Hsu;Wang, Li-Chieh;Lin, Yu-Tsan;Chiang, Bor-Luen +1 more
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Cytokine Profiles and Antibody Response Associated to Choclo Orthohantavirus Infection
Frontiers in Immunology, 2021 BackgroundNew World Hantaviruses (NWHs) are the etiological agent underlying hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with high mortality rates in humans.
Tybbysay P. Salinas +16 more
doaj +1 more source
Human CD4+ Memory T Cells Can Become CD4+IL-9+ T Cells [PDF]
, 2010 Background: IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-β directs mouse CD4+CD25−CD62L+ T cells to commit to inflammatory IL-9 producing CD4+ T cells.
Popoola, Joyce +17 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source