Results 1 to 10 of about 7,622,838 (295)
In vitro potency and pharmacokinetics of APG777, a novel anti–IL-13 mAb [PDF]
Journal of Allergy and Clinical Immunology: GlobalBackground: IL-13 plays a key role in the induction and perpetuation of type 2 immune responses associated with the development of atopic dermatitis and other chronic inflammatory diseases.
Eric Zhu, PhD +8 more
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Vaccines, 2021 We have shown that manipulation of IL-13 and STAT6 signaling at the vaccination site can lead to different innate lymphoid cell (ILC)/dendritic cell (DC) recruitment, resulting in high avidity/poly-functional T cells and effective antibody ...
Zheyi Li, Sreeja Roy, Charani Ranasinghe
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Journal of Pure and Applied Microbiology, 2022 The heterogeneous etiology of asthma makes its diagnosis complicated. Measurement of cytokine levels could be relevant in determining the asthma phenotype, predicting severity, and identifying the treatment type. Enzyme-linked immunosorbent assay (ELISA)
Sawsan M. Jabbar AL-Hasnawi +1 more
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IL-13 Signaling in Liver Fibrogenesis [PDF]
Frontiers in Immunology, 2012 Liver fibrosis is the final common pathway of chronic liver diseases irrespective of etiology. However, etiology deeply impacts progression and characteristics of liver fibrogenesis. IL-13 is the dominant pro-fibrotic cytokine in Schistosomiasis associated liver fibrogenesis. In vitro, IL-13 directly induces expression of fibrosis-associated genes, e.g.
Yan eLiu +4 more
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Vaccines, 2022 Interleukin-4 (IL-4) and interleukin-13 (IL-13) are key cytokines involved in the pathophysiology of both immune-inflammatory and structural changes underlying type 2 asthma.
Corrado Pelaia +8 more
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A Case of Papuloerythroderma Successfully Treated with Dupilumab
Case Reports in Dermatology, 2022 Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching.
Ayaka Mizuno +4 more
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Effects of IL-13 on murine listeriosis [PDF]
International Immunology, 1997 Acquired resistance against Listeria monocytogenes is a typical T helper (Th) 1 dominated immune response, whereas Th2 cytokines are thought to worsen listeriosis. We investigated effects of recombinant IL-13 (rIL-13) on the host response to L. monocytogenes in mice.
Flesch, I., Wandersee, A., Kaufmann, S.
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Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study
Autoimmunity, 2022 Introduction Asthma is a chronic lung disease that injures and constricts the airways. This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways.
Mohammed K. Еlmahdy +3 more
doaj +1 more source
Interleukin-13 (IL-13) Pathway [PDF]
Science's STKE, 2005 Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T H 2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). It is also produced by activated eosinophils.
Ann, Kelly-Welch +2 more
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IL-4/IL-13 axis as therapeutic targets in allergic rhinitis and asthma [PDF]
PeerJ, 2022 Allergic rhinitis (AR) is a common disorder of the upper airway, while asthma is a disease affecting the lower airway and both diseases are usually comorbid.
Siti Muhamad Nur Husna +3 more
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