BALB/c mice deficient in CD4(+) T cell IL-4R alpha expression control Leishmania mexicana load although female but not male mice develop a healer phenotype [PDF]
, 2011 Immunologically intact BALB/c mice infected with Leishmania mexicana develop non-healing progressively growing lesions associated with a biased Th2 response while similarly infected IL-4R alpha-deficient mice fail to develop lesions and develop a robust ...
Owain R Millington +29 more
core +1 more source
IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17-1 [PDF]
, 2011 Copyright information:Taken from "IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17"http://respiratory-research.com/content/8/1/51Respiratory Research 2007;8(1):51-51.Published online
Linda D Martin (79453) +3 more
core +1 more source
Cells, 2023 Asthma is a chronic complex pulmonary disease characterized by airway inflammation, remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and eosinophil-derived neurotoxin (EDN) are two significant mediators involved in the ...
Maciej Tota +4 more
doaj +1 more source
IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17-5 [PDF]
, 2011 Copyright information:Taken from "IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17"http://respiratory-research.com/content/8/1/51Respiratory Research 2007;8(1):51-51.Published online
Linda D Martin (79453) +3 more
core +1 more source
Pathogenesis of Atopic Dermatitis: Current Paradigm [PDF]
Iranian Journal of Immunology, 2019 Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized.
Masutaka Furue +5 more
doaj +1 more source
Differential Effects of Alarmins on Human and Mouse Basophils
Frontiers in Immunology, 2022 Epithelial-derived alarmins (IL-33, TSLP, and IL-25) play an upstream role in the pathogenesis of asthma. Basophil-derived cytokines are a pivotal component of allergic inflammation.
Adriana R. Gambardella +17 more
doaj +1 more source
IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17-6 [PDF]
, 2011 Copyright information:Taken from "IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17"http://respiratory-research.com/content/8/1/51Respiratory Research 2007;8(1):51-51.Published online
Linda D Martin (79453) +3 more
core +1 more source
Selective IL-13 inhibitors for the treatment of atopic dermatitis
Drugs in Context, 2021 Background: Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. AD pathogenesis is multifactorial, involving environmental and genetic factors.
Francisca Gonçalves +2 more
doaj +1 more source
The viability and morphology of IL-13- or IL-13+ cell cultures. [PDF]
, 2019 (A) Percentages of cell viability at the end of cultivation of P0, P1, and P2 cultures and percentages of cell viability of the unattached GC-enriched subpopulation harvested on P1d1.
Pavlina Skalicka (3929549) +4 more
core +1 more source
Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors
Frontiers in Immunology, 2020 Cytokines are small secreted proteins that among many functions also play key roles in the orchestration of inflammation in host defense and disease.
Aurora Holgado +15 more
doaj +1 more source