Results 1 to 10 of about 90,829,949 (240)

Eosinophils, beyond IL-5 [PDF]

open access: yesCells, 2021
New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault   +2 more
doaj   +7 more sources

IL-5 and IL-5 receptor in asthma [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Eosinophils, along with mast cells are key cells involved in the innate immune response against parasitic infection whereas the adaptive immune response is largely dependent on lymphocytes. In chronic parasitic disease and in chronic allergic disease, IL-
ATC Kotsimbos, Q Hamid
doaj   +6 more sources

The role of interleukin-5 (IL-5 ) in vivo: studies with IL-5 deficient mice [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
Eosinophil recruitment is a characteristic feature of a number of pathological conditions and was the topic of the recent International Symposium on allergic inflammation, asthma, parasitic and infectious diseases (Rio de Janeiro, June 3-5, 1996).
Klaus I Matthaei   +2 more
doaj   +4 more sources

German Asthma Net: Characterisation of responders to anti-IL-5 and anti-IL-5(R) therapy

open access: yesPulmonology
Introduction Previous studies of anti-IL-5/IL-5(R) therapies in severe asthma found that response was mainly predicted by indicators of good baseline disease control.
Christina Bal   +14 more
doaj   +5 more sources

Interleukin-5, Interleukin-6 and Eosinophils in COVID-19 Egyptian Patients: Potential Clues for Prognosis and Immunotherapy [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: A decrease in eosinophil levels was found in Corona Virus Disease-19 [COVID-19] patients [eosinopenia]. However, recent research on eosinopenia and disease severity has yielded conflicting results.Objectives: To investigate the relationship ...
Sara Taha   +6 more
doaj   +1 more source

Pollinosis in children and adolescents: modern aspects of pathogenesis and tendencies in therapy

open access: yesАллергология и Иммунология в Педиатрии, 2023
The development of pollinosis in children and adolescents is determined by the influence of genetic and environmental factors. The pathogenetic basis of pollinosis in children and adolescents is the differentiation of Th0 to Th2, activation of Th2cells ...
I. I. Balabolkin
doaj   +1 more source

Evaluation of Serum IL-33, IL-5 and Trace Elements Levels among Asthmatic Patients

open access: yesJournal of Pure and Applied Microbiology, 2022
The precise relationship between interleukins-33 and IL-5, as well as some trace elements and asthma, is unknown. The target of research was to compare and link the above-mentioned serological parameters in asthmatic patients and healthy controls.
Mayada Noori Iqbal   +3 more
doaj   +1 more source

Anti-IL-5 therapies for asthma [PDF]

open access: yesCochrane Database of Systematic Reviews, 2022
This is the second update of previously published reviews in the Cochrane Library (2015, first update 2017). Interleukin-5 (IL-5) is the main cytokine involved in the proliferation, maturation, activation and survival of eosinophils, which cause airway inflammation and are a classic feature of asthma.
Farne, Hugo A   +5 more
openaire   +2 more sources

Study of immunological parameters associated with asthma with and without bacterial infection in Thi-Qar Province [PDF]

open access: yesRomanian Journal of Medical Practice
Background. Asthma is a prevalent and persistent respiratory condition that impacts more than 300 million individuals globally, leading to substantial illness and death. Objective.
Huda Kareem ABBAS, Huda Kareem ABBAS
doaj   +1 more source

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-γ, IL-4, IL-5 and IL-10 with age [PDF]

open access: yes, 2007
Background The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium ...
Mduluza Takafira   +17 more
core   +2 more sources

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