Results 1 to 10 of about 79,335,581 (259)

IL-5 and GM-CSF, but Not IL-3, Promote the Proliferative Properties of Inflammatory-like and Lung Resident-like Eosinophils in the Blood of Asthma Patients

Cells, 2022
Blood eosinophils can be described as inflammatory-like (iEOS-like) and lung-resident-like (rEOS-like) eosinophils. This study is based on the hypothesis that eosinophilopoetins such as interleukin (IL)-3 and IL-5 and granulocyte-macrophage colony ...
Jolita Palacionyte, Andrius Januskevicius, Egle Vasyle, Airidas Rimkunas, Ieva Bajoriuniene, Skaidrius Miliauskas, Kestutis Malakauskas   +6 more
doaj   +1 more source

Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

Neural Regeneration Research, 2023
The noble gas argon has the potential to protect neuronal cells from cell death. So far, this effect has been studied in treatment after acute damage. Preconditioning using argon has not yet been investigated.
Stefanie Scheid, Adrien Lejarre, Jakob Wollborn, Hartmut Buerkle, Ulrich Goebel, Felix Ulbrich   +5 more
doaj   +1 more source

Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor κB in BEAS-2B cells. [PDF]

PLoS ONE, 2014
The airway epithelium may release pro-inflammatory cytokines and chemokines in the asthmatic airway. Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil ...
Michael J O'Sullivan, Nobuaki Hirota, James G Martin   +2 more
doaj   +1 more source

Involvement of 5HT3 Receptors in Anti-Inflammatory Effects of Tropisetron on Experimental TNBS-Induced Colitis in Rat [PDF]

BioImpacts, 2013
Introduction: There is a pressing need for research leading to the development of new effective drugs with lower side effects and more efficacy for treating inflammatory bowel disease (IBD).
Azadeh Motavallian, Mohsen Minaiyan, Mohammad Rabbani, Sasan Andalib, Parvin Mahzouni   +4 more
doaj   +1 more source

Permethrin induced arterial retention of native and oxidized LDL in rats by promoting inflammation, oxidative stress and affecting LDL receptors, and collagen genes

Ecotoxicology and Environmental Safety, 2021
This study is the first to examine the possible mechanism by which long-term exposure to permethrin (PER) can promote arterial retention of proatherogenic lipid and lipoproteins and related vascular dysfunction in rats.
Anouar Feriani, Meriam Tir, Rafik Hachani, Mohamed Salah Allagui, Nizar Tlili, Saber Nahdi, Saleh Alwasel, Abdel Halim Harrath   +7 more
doaj   +1 more source

The role of polymorphism of genes IL5 (–703) and IL5RA (–80) in formation of blood eosinophilia under pulmonary tuberculosis

Бюллетень сибирской медицины, 2012
With attracting contemporary molecular-genetic and immunological research methods, the article analyses etiopathogenetical factors of formation of eosinophilic blood reaction under pulmonary tuberculosis.
K. O. Mikheyeva, V. V. Novitsky, O. I. Urazova, Yu. V. Kolobovnikova, M. D. Goncharov, I. O. Naslednikova   +5 more
doaj   +1 more source

Length-Dependent Modulation of B Cell Activating Factor Transcripts in Chicken Macrophage by Viral Double-Stranded RNA

Vaccines, 2023
Viral double-stranded RNA (dsRNA) interacts with Retinoic-acid-inducible-gene-1 (RIG-1)-like receptors (RLRs) to induce type 1 interferons. Melanoma-derived-antigen-5 (MDA-5), an RLR, but not RIG-1, is found in chickens.
Magda I. Abo-Samaha, Mohammed M. Sharaf, Abeer F. El-Nahas, Solomon O. Odemuyiwa   +3 more
doaj   +1 more source

Suppression of interleukin-1 beta and LDL scavenger receptor expression in macrophages by a selective protein kinase C inhibitor.

Journal of Lipid Research, 1991
A human monocytic cell line, THP-1, stimulated with 40 nM phorbol myristate acetate (PMA), differentiated to macrophage-like cells, and exhibited increased expression and release of interleukin-1 beta and expression of acetylated low density lipoprotein (
AL Akeson, K Schroeder, C Woods, CJ Schmidt, W D Jones   +4 more
doaj   +1 more source

A computational analysis of transcriptional profiles from CD8(+) T lymphocytes reveals potential mechanisms of HIV/AIDS control and progression

Computational and Structural Biotechnology Journal, 2021
Cytotoxic and noncytotoxic CD8+ T lymphocyte responses are essential for the control of HIV infection. Understanding the mechanisms underlying HIV control in elite controllers (ECs), which maintain undetectable viral load in the absence of antiretroviral
Sergey Ivanov, Dmitry Filimonov, Olga Tarasova   +2 more
doaj   +1 more source

Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children

Frontiers in Immunology, 2018
Lower respiratory tract infections (LRTI) are often caused by Streptococcus pneumoniae (Spn) and can be recurrent in 8% of children older than 2 years of age.
Johan N. Siebert, Johan N. Siebert, Lutz Hamann, Charlotte M. Verolet, Cécile Gameiro, Stéphane Grillet, Claire-Anne Siegrist, Claire-Anne Siegrist, Claire-Anne Siegrist, Klara M. Posfay-Barbe, Klara M. Posfay-Barbe   +10 more
doaj   +1 more source