Results 1 to 10 of about 171,953 (311)

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. [PDF]

PLoS Pathogens, 2017
Aspergillus fumigatus causes invasive pulmonary disease in immunocompromised hosts and allergic asthma in atopic individuals. We studied the contribution of lung eosinophils to these fungal diseases.
Evelyn Santos Guerra, Chrono K Lee, Charles A Specht, Bhawna Yadav, Haibin Huang, Ali Akalin, Jun R Huh, Christian Mueller, Stuart M Levitz   +8 more
doaj   +1 more source

Eosinophils and eosinophil-associated diseases: An update [PDF]

Journal of Allergy and Clinical Immunology, 2018
The goal of this series is to offer a survey of the latest literature for clinicians and scientists alike, providing a list of important recent advances relevant to the broad field of allergy and immunology. This particular assignment was to cover the topic of eosinophils. In an attempt to highlight major ideas, themes, trends, and advances relevant to
Jeremy A. O'Sullivan, Bruce S. Bochner
openaire   +2 more sources

Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae.

PLoS Pathogens, 2014
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman, Katherine A Thysse, Siobhan Bearder, Anita Y N Cheung, Ashleigh C Johnston, James J Lee, Rachel A Lawrence   +6 more
doaj   +1 more source

Recent advances of eosinophils and its correlated diseases

Frontiers in Public Health, 2022
Eosinophils are differentiated by bone marrow multipotent progenitor cells and are further released into peripheral blood after maturation. Human eosinophils can exhibit unique multi-leaf nuclear morphology, which are filled with cytoplasmic granules ...
Zhang Tao, Hua Zhu, Hua Zhu, Jiateng Zhang, Jiateng Zhang, Zhiming Huang, Zhiming Huang, Ze Xiang, Ze Xiang, Tu Hong, Tu Hong   +10 more
doaj   +1 more source

Humanized FcεRI Expressed on Mouse Eosinophils Mediates IgE-Facilitated Eosinophil Antigen Presentation

Cells
High-affinity IgE receptors (FcεRI) are expressed on human blood eosinophils and may be upregulated on eosinophils at sites of allergic inflammation including atopic dermatitis and allergic asthma.
Haibin Wang, Jean-Pierre Kinet, Peter F. Weller   +2 more
doaj   +1 more source

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients

Respiratory Research, 2019
Introduction Airway eosinophilic inflammation is a characteristic of asthmatic patients and of a sub group of COPD subjects. Blood eosinophils are deemed as a good surrogate marker of sputum eosinophilic inflammation; however, controversial data have ...
Patrizia Pignatti, Dina Visca, Francesca Cherubino, Elisabetta Zampogna, Etienne Lucini, Laura Saderi, Giovanni Sotgiu, Antonio Spanevello   +7 more
doaj   +1 more source

Eosinophils Exert Antitumorigenic Effects in the Development of Esophageal Squamous Cell CarcinomaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background and Aims: Eosinophils are present in several solid tumors and have context-dependent function. Our aim is to define the contribution of eosinophils in esophageal squamous cell carcinoma (ESCC), as their role in ESCC is unknown.
Justin Jacobse, Zaryab Aziz, Lili Sun, Jasmine Chaparro, Jennifer M. Pilat, Aaron Kwag, Matthew Buendia, Mae Wimbiscus, Motomi Nasu, Tsuyoshi Saito, Shinji Mine, Hajime Orita, Frank Revetta, Sarah P. Short, M. Kay Washington, Girish Hiremath, Michael K. Gibson, Lori A. Coburn, Tatsuki Koyama, Jeremy A. Goettel, Christopher S. Williams, Yash A. Choksi   +21 more
doaj   +1 more source

Eosinophilic Gastritis and Eosinophilic Duodenitis

Current Treatment Options in Gastroenterology, 2022
Abstract Purpose of review This review provides an overview of recent developments in the field of eosinophilic gastritis (EG) and eosinophilic duodenitis (EoD) with emphasis on diagnostic criteria, the clinical manifestation and available or emerging treatments. Recent findings
Sarah Olsson, Nicholas J. Talley, Gerald Holtmann   +2 more
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In vivo visualization of eosinophil secretion in eosinophilic granulomatosis with polyangiitis: An ultrastructural study

Allergology International, 2022
Background: Although eosinophilic granulomatosis with polyangiitis (EGPA) has been considered as a single disease entity belonging to anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, several studies have suggested that in addition to ...
Haruki Koike, Ryoji Nishi, Soma Furukawa, Naohiro Mouri, Yuki Fukami, Masahiro Iijima, Masahisa Katsuno   +6 more
doaj   +1 more source

Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase

Nature Communications
Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow.
Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec   +10 more
doaj   +1 more source