Results 1 to 10 of about 177,144 (212)

Robust Phenotypic Activation of Eosinophils during Experimental Toxocara canis Infection

Frontiers in Immunology, 2018
Eosinophils are multifunctional cells that have cytotoxic proinflammatory activities and stimulate CD4+ T-cells in experimental models of allergy and parasitic infections.
Joice Margareth de Almeida Rodolpho, Luciana Camillo, Márcio Sobreira Silva Araújo, Elaine Speziali, Jordana Grazziela Coelho-dos-Reis, Ricardo de Oliveira Correia, Débora Meira Neris, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Fernanda de Freitas Anibal   +9 more
doaj   +2 more sources

Production of monoclonal antibodies reactive with ovine eosinophils

BMC Immunology, 2007
Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT, Young Anna R, Sansome Georgina M, Bischof Robert J   +3 more
doaj   +1 more source

Dual function of eosinophils in pathogenesis and protective immunity against parasites

Memorias do Instituto Oswaldo Cruz, 1992
The functional duality of eosinophils, involved in a protective response or in pathogenesis is illustrated in various parasitic infections. In schistosomiasis, eosinophils have been shown to mediate schistosomula killing, in the presence of antibodies ...
Monique Capron
doaj   +1 more source

A METHOD FOR DIGITAL QUANTIFICATION OF EOSINOPHILS INFILTRATE IN ORAL SQUAMOUS CELL CARCINOMA [PDF]

Alexandria Dental Journal, 2020
Introduction:The recent advances in tumor immunotherapy triggered more attention towards analysis of tumor inflammation. Oral squamous cell carcinoma (OSCC) is malignancy that can be therapeutically challenging and resistant to treatment.
Rania Younis
doaj   +1 more source

Anti-IL5 Drugs in COVID-19 Patients: Role of Eosinophils in SARS-CoV-2-Induced Immunopathology

Frontiers in Pharmacology, 2021
SARS-CoV-2 infection stimulates a complex activation of the immune system. Eosinophils belong to the host’s defense equipment against respiratory viruses.
Daniele Pala, Daniele Pala, Marco Pistis, Marco Pistis   +3 more
doaj   +1 more source

Prostaglandin D2 and Interleukin-5 Reduce Crth2 Surface Expression on Human Eosinophils

Allergology International, 2004
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified.
Kazuyuki Hamada, Yoshiyuki Yamada, Yumiko Kamada, Shigeharu Ueki, Kazutoshi Yamaguchi, Hajime Oyamada, Miyoshi Fujita, Atsuko Usami, Takahito Chiba, Akira Kanda, Hiroyuki Kayaba, Junichi Chihara   +11 more
doaj   +1 more source

Autophagy Protects against Eosinophil Cytolysis and Release of DNA

Cells, 2022
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault, Paul S. Fichtinger, Karina T. Barretto, Frances J. Fogerty, Ksenija Bernau, Deane F. Mosher, Sameer K. Mathur, Nathan Sandbo, Nizar N. Jarjour   +8 more
doaj   +1 more source

Eosinophils, Stroke-Associated Pneumonia, and Outcome After Mechanical Thrombectomy for Acute Ischemic Stroke

Frontiers in Aging Neuroscience, 2022
BackgroundEosinophils contribute to antibacterial defense by releasing mitochondrial DNA, which are decreased in patients with acute ischemic stroke (AIS).
Zhiliang Guo, Jie Hou, Shuai Yu, Hang Zhang, Shuhong Yu, Huaishun Wang, Jiaping Xu, Shoujiang You, Zhichao Huang, Guodong Xiao, Yongjun Cao, Chun-Feng Liu   +11 more
doaj   +1 more source

UpToDate on eosinophils [PDF]

Exploration of Asthma & Allergy
This review describes the eosinophil journey through the various physiological and pathophysiological phases, from production, maturation, and activation by chemokines and cytokines [especially eotaxin, interleukin (IL)-5, IL-3, and granulocyte ...
Mario Di Gioacchino, Diego Bagnasco, Fulvio Braido, Federica Buta, Pasquale Caponnetto, Roberto Giovanni Carbone, Mario Cazzola, Willem van de Veen, Camilla De Vitis, Linhong Deng, Nelson Rosario Filho, Eva Rebelo Gomes, Giuseppe Guida, Dichapong Kanjanawasee, Nathachit Limjunyawong, Mauro Maniscalco, Mário Morais-Almeida, Giuseppe Murdaca, Jayoung Oh, Giovanni Paoletti, Vincenzo Patella, Ana Margarida Pereira, Graziella Chiara Prezzavento, Francesco Puppo, Chae-Seo Rhee, Erminia Ridolo, Matija Rijavec, Nikoletta Rovina, Franziska Roth-Walter, Pongsakorn Tantilipikorn, Arzu Yorgancıoğlu, Garry Michael Walsh, Torsten Zuberbier, Giorgio Walter Canonica   +33 more
doaj   +1 more source

CD69 Signaling in Eosinophils Induces IL-10 Production and Apoptosis via the Erk1/2 and JNK Pathways, Respectively

Biomolecules
Introduction: Eosinophils contribute to the pathogenesis of allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. We previously reported that human tissue eosinophils have high CD69 expression compared to blood eosinophils, and ...
Dan Van Bui, Linh Manh Nguyen, Akira Kanda, Hanh Hong Chu, Nhi Kieu Thi Le, Yasutaka Yun, Yoshiki Kobayashi, Kensuke Suzuki, Akitoshi Mitani, Akihiro Shimamura, Kenta Fukui, Shunsuke Sawada, David Dombrowicz, Hiroshi Iwai   +13 more
doaj   +1 more source