Results 1 to 10 of about 110,162 (214)

Static and Dynamic Eosinophil Measures and In-Hospital Mortality in Patients with Sepsis: A Retrospective Cohort Study [PDF]

Medicina
Backgroundand Objectives: Reliable prognostic biomarkers in sepsis that are inexpensive and universally available remain limited. Eosinophil counts decrease in systemic illness, but the prognostic value of static versus dynamic eosinophil measures in ...
Florentina Mușat, Octavian Andronic, Alexandra Bolocan, Cosmin-Alexandru Palcău, Alina Mihaela Dobre, Daniel Ion, Dan Nicolae Păduraru   +6 more
doaj   +2 more sources

Transcription Factors in Eosinophil Development and As Therapeutic Targets

Frontiers in Medicine, 2017
Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor
Patricia C. Fulkerson
exaly   +3 more sources

The distribution of blood eosinophil levels in a Japanese COPD clinical trial database and in the rest of the world

International Journal of COPD, 2018
Neil Barnes,1,2 Takeo Ishii,3,4 Nobuyuki Hizawa,5 Dawn Midwinter,6 Mark James,3 Emma Hilton,1 Paul Jones1,71Respiratory Medicine Franchise, GlaxoSmithKline, Brentford, UK; 2William Harvey Research Institute, Barts and The London School of Medicine and ...
Barnes N, Ishii T, Hizawa N, Midwinter D, James M, Hilton E, Jones PW   +6 more
doaj   +3 more sources

Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts

Biomedicines, 2022
Higher blood and sputum eosinophil counts are associated with a greater response to corticosteroids in COPD. Low blood eosinophil counts exhibit greater stability over time whereas higher counts demonstrate more variability.
Augusta Beech, Natalie Jackson, Dave Singh   +2 more
doaj   +1 more source

Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. [PDF]

PLoS ONE, 2013
MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels.
Thomas X Lu, Eun-Jin Lim, Svetlana Itskovich, John A Besse, Andrew J Plassard, Melissa K Mingler, Joelle A Rothenberg, Patricia C Fulkerson, Bruce J Aronow, Marc E Rothenberg   +9 more
doaj   +1 more source

Haematological Predictors of Section Recovery in Dengue Cases [PDF]

National Journal of Laboratory Medicine, 2019
Introduction: Dengue fever is associated with relative increase in haemoglobin, haematocrit and monocyte counts and reduction in platelet counts, eosinophil percentage and absolute eosinophil count.
Sushma Nayar, B Sriranjan, Priyadarshini Shanmugam   +2 more
doaj   +1 more source

Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis [PDF]

Korean Journal of Pediatrics, 2019
Background Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic ...
Yeonu Choi, Haeun Jeon, Eun Ae Yang, Jong-Seo Yoon, Hyun Hee Kim   +4 more
doaj   +1 more source

Clinical and Biological Markers in Hypereosinophilic Syndromes

Frontiers in Medicine, 2017
Hypereosinophilic syndromes (HES) are rare, heterogeneous syndromes characterized by markedly elevated eosinophil counts in the blood and/or tissue and evidence of eosinophil-associated pathology. Although parasitic infections, drug hypersensitivity, and
Paneez Khoury, Michelle Makiya, Amy D. Klion   +2 more
doaj   +1 more source

Eosinophil-mediated cholinergic nerve remodeling [PDF]

, 2006
Eosinophils are observed to localize to cholinergic nerves in a variety of inflammatory conditions such as asthma, rhinitis, eosinophilic gastroenteritis, and inflammatory bowel disease, where they are also responsible for the induction of cell ...
McLean, W.G., Anthony G. Fenech, Madziar, B., Madziar, Beata, Durcan, Niamh, Gleich, G.J., Walsh, M., Fenech, Anthony G., McLean, Graham W., Jan Blusztajn, Gerard J. Gleich, Gleich, Gerard J., Niamh Durcan, Hall, Ian P., Beata Madziar, Walsh, Marie-Therese, Hall, I.P., Ian P. Hall, Durcan, N., Costello, Richard W., Richard W. Costello, Marie-Therese Walsh, McGarvey, Lorcan, Costello, R.W., Fenech, A.G., W. Graham McLean, Lorcan McGarvey, Blusztain, J., Blusztajn, Jan   +28 more
core   +1 more source

The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. [PDF]

, 2021
Eosinophils are a subset of granulocytes characterized by a high abundance of specific granules in their cytoplasm. To act as effector cells, eosinophils degranulate and form eosinophil extracellular traps (EETs), which contain double-stranded DNA (dsDNA)
Aref Hosseini, Fettrelet, T., Yousefi, S., Michael P. Horn, Horn, Michael P., Timothée Fettrelet, Hosseini, A., Dagmar Simon, Shida Yousefi, Stojkov, D., Simon, H.U., Nina Germic, Hosseini, Aref, Alexander Karaulov, Karaulov, Alexander, Yousefi, Shida, Simon, D., Germic, Nina, Stojkov, Darko, Simon, Hans-Uwe, Darko Stojkov, Hans-Uwe Simon, Horn, M.P., Germic, N., Karaulov, A., Simon, Dagmar, Fettrelet, Timothée   +26 more
core   +1 more source