Results 41 to 50 of about 123,808 (307)

Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD) [PDF]

, 2018
Eosinophil-associated diseases (EADs) are rare, heterogeneous disorders characterized by the presence of eosinophils in tissues and/or peripheral blood resulting in immunopathology.
Collins, Margaret M.H., Joseph R Arron, PF Weller (7781321), Khoury, Paneez, Leiferman, Kristen M, KM Leiferman (7781285), Steven J Ackerman, Spencer, Lisa A, P Khoury (7781252), Gerald J Gleich, SJ Ackerman (7781258), Akuthota, Praveen, M Minnicozzi (7781294), Steinfeld, Jonathan, Fulkerson, Patricia C, Fulkerson, Patricia P.C., Minnicozzi, Michael, Leiferman, Kristin, Jean-Emmanuel Kahn, Gopal-Srivastava, Rashmi, Gleich, Gerald J, Kahn, Jean-Emmanuel, JR Arron (7781261), Sameer K Mathur, SK Mathur (7781291), Arron, Joseph R, LA Spencer (7781312), Wechsler, Michael M.E., AJ Wardlaw (7654397), J Steinfeld (7781315), Arron, Joseph J.R., R Gopal-Srivastava (7781279), Ackerman, Steven J, Bruce S Bochner, Elizabeth A Jacobsen, GJ Gleich (7781276), PC Fulkerson (7781273), Prussin, Calman, J-E Kahn (7781270), C Prussin (7781297), Spencer, Lisa L.A., Weller, Peter, Peter F Weller, ME Wechsler (7781318), Sable, Kathleen, Wardlaw, Andrew J, Hans-Uwe Simon, Wechsler, Michael E, Amy D Klion, Francesca, Levi-Schaffer, Kathleen Sable, Rothenberg, Marc, Francesca, Levi Schaffer, P Akuthota (7781255), Ackerman, Steven S.J., Bochner, Bruce B.S., Bochner, Bruce S, Paneez Khoury, D Simon (7781309), Weller, Peter F, Wardlaw, Andrew, Patricia C Fulkerson, MH Collins (7781267), Jacobsen, Elizabeth A, Rothenberg, Marc E, Jonathan Steinfeld, Roufosse, Florence, Michael Minnicozzi, Mathur, Sameer S.K., ME Rothenberg (7781300), Michael E Wechsler, Florence Roufosse, EA Jacobsen (7781282), Marc E Rothenberg, Jacobsen, Elizabeth E.A., Margaret H Collins, L-S Francesca (7781288), AD Klion (7781324), Praveen Akuthota, Kristen M Leiferman, Lisa A Spencer, Dagmar Simon, Andrew J Wardlaw, K Sable (7781306), Klion, Amy D, Calman Prussin, H-U Simon (7737986), BS Bochner (7781264), Gleich, Gerald G.J., Simon, Hans-Uwe, Klion, Amy, Rashmi Gopal-Srivastava, F Roufosse (7781303), Mathur, Sameer K, Simon, Dagmar, Collins, Margaret H, Levi-Schaffer Francesca, Arron JR, Leiferman KM, Ackerman, Steven J., Wardlaw, Andrew J., Fulkerson, Patricia C., Prussin C, Simon HU, Gleich GJ, Kahn JE, Fulkerson PC, Weller PF, Collins, Margaret H., Klion AD, Collins MH, Jacobsen EA, Jacobsen, Elizabeth A., Simon D, Gleich, Gerald J., Rothenberg, Marc E., Wechsler, Michael E., Bochner, Bruce S., Francesca LS, Spencer LA, Gopal-Srivastava R, Bochner BS, Roufosse F, Mathur SK, Khoury P, Ackerman SJ, Akuthota P, Steinfeld J, Weller, Peter F., Sable K, Wechsler ME, Klion, Amy D., Spencer, Lisa A., Minnicozzi M, Rothenberg ME, Wardlaw AJ, Mathur, Sameer K., Arron, Joseph R., Leiferman, Kristen M.   +138 more
core   +1 more source

Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase

, 2008
Nitration of tyrosine residues has been observed during various acute and chronic inflammatory diseases. However, the mechanism of tyrosine nitration and the nature of the proteins that become tyrosine nitrated during inflammation remain unclear. Here we
Kita, H., Schwarz, Heinz, Markus Schirle, Ralph S. Pero, Shimokawa, H., Alina Petre, Döring, Gerd, Thiyagarajan, N., Gabriel Bellon, Schirle, M. ; https://orcid.org/, Acharya, K., Alfred Doyle, Doyle, Alfred, Schumm, Michael, Schirle, Markus, Martina Ulrich, Przybylski, Michael, Prömm, F., Acharya, K Ravi, Checkel, James, Simon, H., Przybylski, M., Gerd Döring, Tsutsui, Masato, Bellon, Gabriel, Heinz Schwarz, Doyle, A., Tsutsui, M., Ulrich, M., Masato Tsutsui, Petre, Alina, Youhnovski, Nikolay, Hirohito Kita, Nethaji Thiyagarajan, Schmid-Grendelmeier, Peter, Petre, A., Nikolay Youhnovski, Peter Schmid-Grendelmeier, Pero, R., K. Ravi Acharya, Youhnovski, N., Lee, J., Hiroaki Shimokawa, Shimokawa, Hiroaki, Michael Przybylski, Schumm, M., Kita, Hirohito, Acharya, K. Ravi, Petre, Brînduşa-Alina, Bellon, G., Ulrich, Martina, Pero, Ralph S, Thiyagarajan, Nethaji, Simon, Hans-Uwe, Lee, James J, Hans-Uwe Simon, Schwarz, H., Prömm, Franziska, Döring, G., James Checkel, Schmid-Grendelmeier, P., Checkel, J., Michael Schumm, Pero, Ralph S., Lee, James J., Franziska Prömm, James J. Lee   +66 more
core   +1 more source

Static and Dynamic Eosinophil Measures and In-Hospital Mortality in Patients with Sepsis: A Retrospective Cohort Study

Medicina
Backgroundand Objectives: Reliable prognostic biomarkers in sepsis that are inexpensive and universally available remain limited. Eosinophil counts decrease in systemic illness, but the prognostic value of static versus dynamic eosinophil measures in ...
Florentina Mușat, Octavian Andronic, Alexandra Bolocan, Cosmin-Alexandru Palcău, Alina Mihaela Dobre, Daniel Ion, Dan Nicolae Păduraru   +6 more
doaj   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Eosinophilic Gastritis and Eosinophilic Duodenitis

Current Treatment Options in Gastroenterology, 2022
Abstract Purpose of review This review provides an overview of recent developments in the field of eosinophilic gastritis (EG) and eosinophilic duodenitis (EoD) with emphasis on diagnostic criteria, the clinical manifestation and available or emerging treatments. Recent findings
Sarah Olsson, Nicholas J. Talley, Gerald Holtmann   +2 more
openaire   +1 more source

Evaluation of association of blood and bronchoalveolar eosinophil numbers and serum total immunoglobulin E concentration with the expression of nonspecific airway reactivity in dogs [PDF]

, 1997
To characterize the relation between bronchoalveolar and blood eosinophil numbers, serum total IgE concentration, and nonspecific airway reactivity in healthy ...
Muggenburg, B A, Bice, D E, DeBoer, D J, Collie, D D   +3 more
core  

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

A case of eosinophilic gastroenteritis with eosinophilic ascites.

Nihon Naika Gakkai Zasshi, 1989
48才の女性が,水様性下痢便に続く著明な腹水で,近医より紹介された.末梢血白血球分画で好酸球が42%と著増を示し,また,腹水中の好酸球が84%を占めていた.開腹による小腸楔状切除生検にて,粘膜下層から漿膜下層にわたるほぼ全層に,好酸球の浸潤を認めた.これらから,本例はいわゆるMcNabbらの言うtransmural eosinophilic gastroenteritis with ascitesに相当すると思われる.
HARIGANE, Mitsuya, OHARA, Hiroyasu, KAWAMURA, Osamu, NAGAI, Kunio, GENDA, Akira, NAGAO, Mamoru   +5 more
openaire   +3 more sources

Eosinophil-mediated tissue inflammatory responses in helminth infection. [PDF]

, 2009
Eosinophilic leukocytes function in host protection against parasitic worms. In turn, helminthic parasites harbor specific molecules to evade or paralyze eosinophil-associated host immune responses; these molecules facilitate the migration and survival ...
이영아, Young Ah Lee, Duk-Young Min, 신명헌, Myeong Heon Shin   +4 more
core   +1 more source