Results 51 to 60 of about 237,523 (354)

Esophageal Squamous Cell Carcinoma with Marked Eosinophil Infiltration

Case Reports in Gastroenterology, 2011
We report a case of esophageal squamous cell carcinoma (SCC) with marked eosinophil infiltration which was identified postoperatively in the esophageal wall in areas not surrounding the SCC.
Minoru Fukuchi, Shinji Sakurai, Masaki Suzuki, Hiroshi Naitoh, Yuichi Tabe, Takaharu Fukasawa, Shinsuke Kiriyama, Takehiko Yokobori, Hiroyuki Kuwano   +8 more
doaj   +1 more source

Prediction value of neutrophil and eosinophil count at risk of COPD exacerbation

Annals of Medicine, 2023
Introduction Predicting acute exacerbations (AEs) in chronic obstructive pulmonary disease (COPD) is crucial. This study aimed to identify blood biomarkers for predicting COPD exacerbations by inflammatory phenotypes.Materials and methods We analyzed ...
Tzu-Tao Chen, Kang-Yun Lee, Jer-Hwa Chang, Chi-Li Chung, Huan Minh Tran, Amja Manullang, Shu-Chuan Ho, Kuan-Yuan Chen, Chien-Hua Tseng, Sheng-Ming Wu, Hsiao-Chi Chuang   +10 more
doaj   +1 more source

Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil Counts.

Chest, 2016
BACKGROUND IL-5, a mediator of eosinophil activity, is an important potential treatment target in patients with uncontrolled asthma. The efficacy of reslizumab, a humanized anti-human IL-5 monoclonal antibody, has been characterized in patients with ...
J. Corren, S. Weinstein, L. Janka, J. Zangrilli, M. Garin   +4 more
semanticscholar   +1 more source

Identification of autoantigens and their potential post-translational modification in EGPA and severe eosinophilic asthma

Frontiers in Immunology, 2023
BackgroundThe chronic airway inflammation in severe eosinophilic asthma (SEA) suggests potential autoimmune aetiology with unidentified autoantibodies analogous to myeloperoxidase (MPO) in ANCA-positive EGPA (eosinophilic granulomatosis with polyangiitis)
Ilaria Esposito, Ioanna Kontra, Chiara Giacomassi, Chiara Giacomassi, Sotiria Manou-Stathopoulou, James Brown, Richard Stratton, Richard Stratton, Galateia Verykokou, Roberto Buccafusca, Michael Stevens, Michael Stevens, Ahuva Nissim, Myles J. Lewis, Paul E. Pfeffer, Paul E. Pfeffer   +15 more
doaj   +1 more source

The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
K. Amber, Manuel Valdebran, K. Kridin, S. Grando   +3 more
semanticscholar   +1 more source

Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. [PDF]

, 2019
There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking.
Aceves, Seema S, Adejumobi, Dolapo, Akuthota, Praveen, Dohil, Ranjan, Duong, Loan D, Jones, Stacie M, Kurten, Richard C, Levy, Rebecca, Newbury, Robert O, Rawson, Renee, Rothenberg, Marc E, Shoda, Tetsuo, Wright, Benjamin L   +12 more
core   +3 more sources

Static and Dynamic Eosinophil Measures and In-Hospital Mortality in Patients with Sepsis: A Retrospective Cohort Study

Medicina
Backgroundand Objectives: Reliable prognostic biomarkers in sepsis that are inexpensive and universally available remain limited. Eosinophil counts decrease in systemic illness, but the prognostic value of static versus dynamic eosinophil measures in ...
Florentina Mușat, Octavian Andronic, Alexandra Bolocan, Cosmin-Alexandru Palcău, Alina Mihaela Dobre, Daniel Ion, Dan Nicolae Păduraru   +6 more
doaj   +1 more source

Eosinophilic Pneumonias [PDF]

Clinical Microbiology Reviews, 2012
SUMMARY This review starts with discussions of several infectious causes of eosinophilic pneumonia, which are almost exclusively parasitic in nature. Pulmonary infections due specifically to Ascaris , hookworms, Strongyloides , Paragonimus , filariasis, and
Akuthota, P., Weller, Peter
openaire   +3 more sources

Remission of Kimura disease with carotid hypervascularization after cyclosporine treatment [PDF]

, 2020
No abstract ...
Bartolazzi, Armando, Persechino, Flavia, Persechino, Severino, Raffa, Salvatore, Tammaro, Antonella, Torrisi, Maria Rosaria, Valente, Sabatino, Visco, Vincenzo   +7 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source