Results 61 to 70 of about 123,808 (307)

Secretory Leukocyte Protease Inhibitor Is Present in Circulating and Tissue-Recruited Human Eosinophils and Regulates Their Migratory Function

Frontiers in Immunology, 2022
Eosinophils and secretory leukocyte protease inhibitor (SLPI) are both associated with Th2 immune responses and allergic diseases, but whether the fact that they are both implicated in these conditions is pathophysiologically related remains unknown ...
Oktawia Osiecka, Joanna Skrzeczynska-Moncznik, Agnieszka Morytko, Angelika Mazur, Pawel Majewski, Bernadetta Bilska, Monika Kapinska-Mrowiecka, Joanna Kosalka-Wegiel, Joanna Kosalka-Wegiel, Maciej Pastuszczak, Elzbieta Pyza, Joanna Cichy   +11 more
doaj   +1 more source

Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes

, 1998
Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are generally regarded as eosinophil-specific proteins. We tested whether EDN and ECP are present in mature neutrophils.
Jill M Wagner, Hirohito Kita, Terry J George, Stephen M Kujawa, Kristin M Leiferman, Sanjiv Sur, Ellen A Peterson, Deborah A Weiler, Gail M Kephart, Gerald J Gleich, Dohn G Glitz   +10 more
core   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Eosinophil - 1

, 2014
An image from a normal peripheral blood smear showing an ...
Fraser, Marion
core   +1 more source

Eosinophil and Eosinophil Cationic Protein Level Raising in Dermatitis Due to Food Patients [PDF]

, 2016
Background: Food allergy prevalence worldwide has been increase. Skin is secondary most often target organ in food allergy reaction. Food allergy affects 35% atopic dermatitis (AD) patients. Diagnosis of food allergy  is still challenge because signs are
Sawitri, Sawitri, Umborowati, Menul Ayu, Hoetomo, Marsoedi   +2 more
core   +2 more sources

Differential Diagnosis of Mucopolysaccharidoses Types I, II, III, IVA, and VI Through Analysis of Leukocytic Inclusions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with different types of MPS and assess their diagnostic relevance.
Márcio A. W. Melo, Marcelo S. Kertenetzky, Cristina M. Silveira, Maíra M. Ribeiro, Paula F. Medeiros, Gabriela S. Arcanjo   +5 more
wiley   +1 more source

Eosinophilic Gastroenteritis and Related Eosinophilic Disorders [PDF]

Gastroenterology Clinics of North America, 2014
Eosinophilic gastroenteritis (EGE) represents one member within the spectrum of diseases collectively referred to as eosinophilic gastrointestinal disorders, which includes eosinophilic esophagitis (EoE), gastritis, enteritis, and colitis. EGE is less common than EoE and involves a different site of disease but otherwise shares many common features ...
openaire   +2 more sources

Expression and function of beta1 integrins on human eosinophils [PDF]

Memorias do Instituto Oswaldo Cruz, 1997
Eosinophils preferentially accumulate at sites of chronic allergic diseases such as bronchial asthma. The mechanisms by which selective eosinophil migration occurs are not fully understood.
Maria-Cristina Seminario, Bruce S Bochner   +1 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source