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Metabolic Profiling of Human Eosinophils [PDF]
Immune cells face constant changes in their microenvironment, which requires rapid metabolic adaptation. In contrast to neutrophils, which are known to rely near exclusively on glycolysis, the metabolic profile of human eosinophils has not been ...
Linsey Porter +6 more
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Eosinophils in skin diseases. [PDF]
Eosinophil infiltration is a common finding in a broad spectrum of skin diseases, despite the fact that the skin is devoid of eosinophils under physiologic conditions. Although cutaneous eosinophilia is reactive, cytokine-mediated in most cases, diseases
Simon, Hans-Uwe +4 more
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Eosinophils from A to Z. [PDF]
Eosinophils are bone marrow-derived granulocytes and are found in low numbers in the peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the bone marrow is increased, resulting in a rise in the number of mature ...
Simon, Hans-Uwe +9 more
core +1 more source
Basophils Orchestrating Eosinophils' Chemotaxis and Function in Allergic Inflammation. [PDF]
Eosinophils are well known to contribute significantly to Th2 immunity, such as allergic inflammations. Although basophils have often not been considered in the pathogenicity of allergic dermatitis and asthma, their role in Th2 immunity has become ...
Fux, Michaela +3 more
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A Study of Eosinophils – From the Human Thymus to Eosinophilic Esophagitis [PDF]
Eosinophils are cells of the innate immune system. They primarily reside within tissues and are most numerous in the gastrointestinal tract but are absent from the healthy esophagus.
Albinsson Högberg, Sofie
core +1 more source
New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault +2 more
doaj +1 more source
Eosinophils in eosinophilic pneumonia [PDF]
Idiopathic eosinophilic pneumonia (IEP) is an uncom-mon disease of unknown aetiology characterized by theaccumulation of eosinophils in the lung, variable bloodeosinophilia and peripheral opacities on the chest radio-gram. The response to steroid treatment is dramatic butrelapses are frequent, requiring the use of long-termsteroid treatment [1 ...
C Albera, P Ghio
openaire +1 more source
Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
A. E. Heufelder +9 more
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Production of monoclonal antibodies reactive with ovine eosinophils
Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT +3 more
doaj +1 more source
Dual function of eosinophils in pathogenesis and protective immunity against parasites
The functional duality of eosinophils, involved in a protective response or in pathogenesis is illustrated in various parasitic infections. In schistosomiasis, eosinophils have been shown to mediate schistosomula killing, in the presence of antibodies ...
Monique Capron
doaj +1 more source

