Results 21 to 30 of about 177,144 (212)

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. [PDF]

, 2018
Eosinophils are predominantly known for their contribution to allergy. Here, we have examined the function and regulation of gastrointestinal eosinophils in the steady-state and during infection with or We find that eosinophils are recruited to sites ...
Taube, Christian, Maries van den Broek, Ottemann, Karen, Anne Müller, Kyburz, Andreas, Yousefi, Shida, Müller, Anne, Paulino Tallón de Lara, Andreas Kyburz, Simon, Hans-Uwe, Hans-Uwe Simon, Arnold, Isabelle C, Tallón de Lara, Paulino, Isabelle C. Arnold, Karen Ottemann, Shida Yousefi, Artola-Borán, Mariela, van den Broek, Maries, de Lara, Paulino Tallón, Christian Taube, Mariela Artola-Borán   +20 more
core   +4 more sources

CD44 on blood eosinophils as a novel marker of bronchial asthma management

Allergology International, 1998
Bronchial asthma (BA) is characterized by infiltration of the respiratory tracts by eosinophils. A wide variety of adhesion molecules is involved in the binding of eosinophils to the vascular endothelium and their subsequent transmigration from the ...
Kunio Sano, Kohei Yamauchi, Hiroki Hoshi, Masaaki Honma, Gen Tamura, Kunio Shirato   +5 more
doaj   +1 more source

Role of IL-25 on Eosinophils in the Initiation of Th2 Responses in Allergic Asthma

Frontiers in Immunology, 2022
BackgroundEosinophils act as a secondary antigen-presenting cell (APC) to stimulate Th cell responses against antigens. IL-25 plays a significant role in eosinophil activation in allergic asthma.
Bo Peng, Bo Peng, Bo Peng, Lin Sun, Lin Sun, Lin Sun, Meng Zhang, Huacheng Yan, Huacheng Yan, Huacheng Yan, Guochao Shi, Guochao Shi, Guochao Shi, Zhenwei Xia, Ranran Dai, Ranran Dai, Ranran Dai, Wei Tang, Wei Tang, Wei Tang   +19 more
doaj   +1 more source

Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding

Pharmacology Research & Perspectives, 2020
Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros, Tamara Dekker, Barbara Smids, Christof J. Majoor, Lara Ravanetti, Gino Villetti, Maurizio Civelli, Fabrizio Facchinetti, René Lutter   +8 more
doaj   +1 more source

Eosinophils, beyond IL-5

Cells, 2021
New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault, Mats W Johansson, Sameer K Mathur   +2 more
doaj   +1 more source

Active eosinophils regulate host defense and immune responses in colitis. [PDF]

, 2023
In the past decade, single-cell transcriptomics has helped uncover new cell types and states and led to the construction of a cellular compendium of health and disease1.
Raju, Deeksha, Krebs, Philippe, Acar, Ilhan E, Schneider, Christoph; id_orcid, Valenta, Tomas, Gurtner, Alessandra, Basler, Konrad, Stirm, Kristin, Arnold, Isabelle C, Slack, Emma, Gschwend, Julia, Vu, Vivian P., Núñez, Nicolás, Schneider, Christoph, Becher, Burkhard, Núñez, Nicolás G, Núñez, Nicolás G., Crepaz, Daniel, Moor, Andreas E, Gonzalez Perez, Ignacio, Bach, Karsten, Vu, Vivian P, Lafzi, Atefeh, Moor, Andreas E., Acar, Ilhan E., Borrelli, Costanza, Moor, Andreas; id_orcid, Arnold, Isabelle C., Handler, Kristina, Slack, Emma; id_orcid, Gonzalez-Perez, Ignacio, Valenta, Tomas; https://orcid.org/, Schneider, Christoph; https://orcid.org/, Slack, Emma; https://orcid.org/, Basler, Konrad; https://orcid.org/, Gschwend, Julia; https://orcid.org/, Arnold, Isabelle C; https://orcid.org/, Moor, Andreas E; https://orcid.org/, Becher, Burkhard; https://orcid.org/   +38 more
core   +2 more sources

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]

, 1996
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
A. E. Heufelder, J. R. Goellner, Gleich, G. J., I. D. Hay, Bahn, R. S., R. S. Bahn, Hay, I. D., Heufelder, Armin E., Goellner, J. R., G. J. Gleich   +9 more
core   +1 more source

Basophils Orchestrating Eosinophils' Chemotaxis and Function in Allergic Inflammation. [PDF]

, 2021
Eosinophils are well known to contribute significantly to Th2 immunity, such as allergic inflammations. Although basophils have often not been considered in the pathogenicity of allergic dermatitis and asthma, their role in Th2 immunity has become ...
Fux, Michaela, Joseena Iype, Iype, Joseena, Michaela Fux   +3 more
core   +2 more sources

Eosinophilic Pneumonia with Eosinophilic Gastroenteritis.

Internal Medicine, 1999
A 48-year-old man was admitted to our hospital with cough, fever and dysphagia. He had a past history of bronchial asthma and surgery for nasal polyp. Chest radiograph and computed tomography showed atelectasis in the right lower field and infiltrative shadow in the left lower field and overall thickening of the esophageal wall.
MIYAZONO, Takahito, KAWABATA, Masaharu, HIGASHIMOTO, Ikkou, KOREEDA, Yoshifusa, IWAKIRI, Yuuji, ARIMURA, Kimiyoshi, OSAME, Mitsuhiro   +6 more
openaire   +3 more sources