Results 41 to 50 of about 177,144 (212)

Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?

Frontiers in Immunology, 2021
Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Inge Jacobs, Matthias Ceulemans, Lucas Wauters, Lucas Wauters, Christine Breynaert, Christine Breynaert, Séverine Vermeire, Séverine Vermeire, Bram Verstockt, Bram Verstockt, Tim Vanuytsel, Tim Vanuytsel   +11 more
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Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma

Allergy, Asthma & Clinical Immunology, 2018
Background The fractional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of eosinophilic airway inflammation used in the diagnosis and management of asthma, although induced sputum is the gold standard test for phenotypic asthma ...
Jie Gao, Feng Wu
doaj   +1 more source

Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. [PDF]

PLoS Pathogens, 2017
Aspergillus fumigatus causes invasive pulmonary disease in immunocompromised hosts and allergic asthma in atopic individuals. We studied the contribution of lung eosinophils to these fungal diseases.
Evelyn Santos Guerra, Chrono K Lee, Charles A Specht, Bhawna Yadav, Haibin Huang, Ali Akalin, Jun R Huh, Christian Mueller, Stuart M Levitz   +8 more
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The Role of Eosinophils in Viral Infections

, 2021
Respiratory viruses are a leading cause of severe respiratory infections normally seen in infants and children. As there is currently no known vaccine against major respiratory viruses, the pressure is on the innate immune cells to clear these infections
Townsend, Dijana, Simson, Ljubov
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Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae.

PLoS Pathogens, 2014
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman, Katherine A Thysse, Siobhan Bearder, Anita Y N Cheung, Ashleigh C Johnston, James J Lee, Rachel A Lawrence   +6 more
doaj   +1 more source

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients

Respiratory Research, 2019
Introduction Airway eosinophilic inflammation is a characteristic of asthmatic patients and of a sub group of COPD subjects. Blood eosinophils are deemed as a good surrogate marker of sputum eosinophilic inflammation; however, controversial data have ...
Patrizia Pignatti, Dina Visca, Francesca Cherubino, Elisabetta Zampogna, Etienne Lucini, Laura Saderi, Giovanni Sotgiu, Antonio Spanevello   +7 more
doaj   +1 more source

Recent advances of eosinophils and its correlated diseases

Frontiers in Public Health, 2022
Eosinophils are differentiated by bone marrow multipotent progenitor cells and are further released into peripheral blood after maturation. Human eosinophils can exhibit unique multi-leaf nuclear morphology, which are filled with cytoplasmic granules ...
Zhang Tao, Hua Zhu, Hua Zhu, Jiateng Zhang, Jiateng Zhang, Zhiming Huang, Zhiming Huang, Ze Xiang, Ze Xiang, Tu Hong, Tu Hong   +10 more
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Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization. [PDF]

, 2022
The intestine harbors a large population of resident eosinophils, yet the function of intestinal eosinophils has not been explored. Flow cytometry and whole-mount imaging identified eosinophils residing in the lamina propria along the length of the ...
Hamelin, R., McDonald, B., Koeller, Yasmin, Petrova, T.V., Shah, Kathleen, Ignacio, Aline, Harris, Nicola L, Wang, H., Shah, K., Dufour, A., McCoy, K.D., Wong, N.C., Burkhard, R., Hamelin, Romain, Coakley, G., Burkhard, Regula, Thomson, Carolyn A, Petrova, Tatiana V, Moyat, M., Ramay, H., Wang, Haozhe, Ignacio, A., Moyat, Mati, Armand, Florence, McCoy, Kathy D, Wong, Nick C, McDonald, Braedon, Geuking, Markus B., Coakley, Gillian, Thomson, Carolyn A., Dufour, Antoine, Harris, N.L., Ramay, Hena, Geuking, Markus B, Bernier-Latmani, Jeremiah, Petrova, Tatiana, V, Armand, F., Thomson, C.A., McCoy, Kathy D., Bernier-Latmani, J., Köller, Yasmin, Köller, Y., Geuking, M.B., Wong, Nick C., Harris, Nicola L., Nick C. Wong, Antoine Dufour, Markus B. Geuking, Aline Ignacio, Florence Armand, Carolyn A. Thomson, Mati Moyat, Tatiana V. Petrova, Romain Hamelin, Jeremiah Bernier-Latmani, Haozhe Wang, Braedon McDonald, Hena Ramay, Nicola L. Harris, Yasmin Köller, Kathleen Shah, Regula Burkhard, Kathy D. McCoy, Gillian Coakley   +63 more
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Eosinophils Exert Antitumorigenic Effects in the Development of Esophageal Squamous Cell CarcinomaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background and Aims: Eosinophils are present in several solid tumors and have context-dependent function. Our aim is to define the contribution of eosinophils in esophageal squamous cell carcinoma (ESCC), as their role in ESCC is unknown.
Justin Jacobse, Zaryab Aziz, Lili Sun, Jasmine Chaparro, Jennifer M. Pilat, Aaron Kwag, Matthew Buendia, Mae Wimbiscus, Motomi Nasu, Tsuyoshi Saito, Shinji Mine, Hajime Orita, Frank Revetta, Sarah P. Short, M. Kay Washington, Girish Hiremath, Michael K. Gibson, Lori A. Coburn, Tatsuki Koyama, Jeremy A. Goettel, Christopher S. Williams, Yash A. Choksi   +21 more
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High Transcriptional Activity and Clinical Correlations in Eosinophils of Patients with Late-Onset Asthma

, 2023
Ting-Yu Lin,1,2 Chun-Yu Lo,1,2 Po-Jui Chang,1,2 Yu-Lun Lo,1,2 Chung-Shu Lee,1– 3 Chih-Hao Chang,1– 3 Chih-Teng Yu,1,2 Jonathan Huai Yao,1 Shu-Min Lin1,2 1Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan; 2College of Medicine,
Lo YL, Lo CY, Lin SM, Lee CS, Chang CH, Lin TY, Yu CT, Yao JH, Chang PJ   +8 more
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