Results 41 to 50 of about 161,284 (313)

Eosinophils as putative therapeutic targets in bullous pemphigoid. [PDF]

open access: yes, 2017
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering skin disease and is characterized by the presence of autoantibodies directed against the hemidesmosomal proteins BP180 and BP230 that can be detected in the skin and serum of ...
Simon, Hans-Uwe   +5 more
core   +1 more source

The Role of Eosinophils in Viral Infections

open access: yes, 2021
Respiratory viruses are a leading cause of severe respiratory infections normally seen in infants and children. As there is currently no known vaccine against major respiratory viruses, the pressure is on the innate immune cells to clear these infections
Townsend, Dijana, Simson, Ljubov
core  

Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae.

open access: yesPLoS Pathogens, 2014
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman   +6 more
doaj   +1 more source

Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma

open access: yesAllergy, Asthma & Clinical Immunology, 2018
Background The fractional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of eosinophilic airway inflammation used in the diagnosis and management of asthma, although induced sputum is the gold standard test for phenotypic asthma ...
Jie Gao, Feng Wu
doaj   +1 more source

Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?

open access: yesFrontiers in Immunology, 2021
Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Inge Jacobs   +11 more
doaj   +1 more source

Eosinophils and eosinophil-associated diseases: An update [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2018
The goal of this series is to offer a survey of the latest literature for clinicians and scientists alike, providing a list of important recent advances relevant to the broad field of allergy and immunology. This particular assignment was to cover the topic of eosinophils. In an attempt to highlight major ideas, themes, trends, and advances relevant to
Jeremy A. O'Sullivan, Bruce S. Bochner
openaire   +2 more sources

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients

open access: yesRespiratory Research, 2019
Introduction Airway eosinophilic inflammation is a characteristic of asthmatic patients and of a sub group of COPD subjects. Blood eosinophils are deemed as a good surrogate marker of sputum eosinophilic inflammation; however, controversial data have ...
Patrizia Pignatti   +7 more
doaj   +1 more source

Recent advances of eosinophils and its correlated diseases

open access: yesFrontiers in Public Health, 2022
Eosinophils are differentiated by bone marrow multipotent progenitor cells and are further released into peripheral blood after maturation. Human eosinophils can exhibit unique multi-leaf nuclear morphology, which are filled with cytoplasmic granules ...
Zhang Tao   +10 more
doaj   +1 more source

The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. [PDF]

open access: yes, 2020
Eosinophils and their secretory mediators play an important role in the pathogenesis of infectious and inflammatory disorders. Although eosinophils are largely evolutionally conserved, their physiologic functions are not well understood.
Simon, Hans-Uwe   +10 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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