Results 51 to 60 of about 171,953 (311)

Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?

open access: yesFrontiers in Immunology, 2021
Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Inge Jacobs   +11 more
doaj   +1 more source

The Role of Eosinophils in Viral Infections

open access: yes, 2021
Respiratory viruses are a leading cause of severe respiratory infections normally seen in infants and children. As there is currently no known vaccine against major respiratory viruses, the pressure is on the innate immune cells to clear these infections
Townsend, Dijana, Simson, Ljubov
core  

Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma

open access: yesAllergy, Asthma & Clinical Immunology, 2018
Background The fractional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of eosinophilic airway inflammation used in the diagnosis and management of asthma, although induced sputum is the gold standard test for phenotypic asthma ...
Jie Gao, Feng Wu
doaj   +1 more source

Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD. [PDF]

open access: yes, 2016
INTRODUCTION: Sputum eosinophilia occurs in approximately one-third of stable chronic obstructive pulmonary disease (COPD) patients and can predict exacerbation risk and response to corticosteroid treatments. Sputum induction, however, requires expertise,
Gibson, PG   +13 more
core   +1 more source

The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. [PDF]

open access: yes, 2020
Eosinophils and their secretory mediators play an important role in the pathogenesis of infectious and inflammatory disorders. Although eosinophils are largely evolutionally conserved, their physiologic functions are not well understood.
Simon, Hans-Uwe   +10 more
core   +2 more sources

Active eosinophils regulate host defense and immune responses in colitis. [PDF]

open access: yes, 2023
In the past decade, single-cell transcriptomics has helped uncover new cell types and states and led to the construction of a cellular compendium of health and disease1.
Raju, Deeksha   +30 more
core   +2 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

The Role of Saturated Fatty Acids in Connexin Expression on Endothelial Cells and Eosinophils [PDF]

open access: yes, 2012
Eotaxin is a potent chemoattractant for eosinophils that becomes elevated in the tissues in response to inflammation and increased adiposity. Therefore, eosinophil migration into adipose tissue should increase in diet-induced obese individuals, yet it ...
Ashack, Kurt Anthony
core  

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

High Transcriptional Activity and Clinical Correlations in Eosinophils of Patients with Late-Onset Asthma

open access: yes, 2023
Ting-Yu Lin,1,2 Chun-Yu Lo,1,2 Po-Jui Chang,1,2 Yu-Lun Lo,1,2 Chung-Shu Lee,1– 3 Chih-Hao Chang,1– 3 Chih-Teng Yu,1,2 Jonathan Huai Yao,1 Shu-Min Lin1,2 1Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan; 2College of Medicine,
Lo YL   +8 more
core  

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