Results 1 to 10 of about 673,896 (307)

Structural insight into interleukin‐4Rα and interleukin‐5 inhibition by nanobodies from a bispecific antibody [PDF]

MedComm
Weicheng Qiu, Jinguo Meng, Zhipeng Su, Wei Xie, Gaojie Song   +4 more
doaj   +2 more sources

The role of interleukin-4 and interleukin-5 Th2 cytokines in assessing severity and prognosis of acute pancreatitis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction/Objective. Acute pancreatitis (AP) is a relatively common disease which in most patients has favorable course. However, in approximately 20% patients, the course of the disease is more severe with high mortality (40–50%).
Doklestić Krstina, Ivančević Nenad, Lončar Zlatibor, Micić Dušan, Ristić Miloš, Jovanović Bojan, Gregorić Pavle   +6 more
doaj   +1 more source

Bronchial asthma and interleukin-5 [PDF]

Respiratory Research, 2001
Das Undurti, Leckie MJ, Brinke A, Khan J, Diamant Z, O'Connor BJ, Walls CM, Mathur AK, Cowley HC, Chung KF, Djukanovic R, Hansel TT, Holgate ST, Sterk PJ, Barnes PJ   +14 more
doaj   +2 more sources

Evaluation of IL-3, IL-5, and IL-6 concentration in the follicular fluid of women with endometriosis: A cross-sectional study

International Journal of Reproductive BioMedicine, 2022
Background: Endometriosis is associated with abnormal immunologic responses and combined inflammatory and anti-inflammatory conditions. Objective: This study aims to investigate follicular fluid (FF) concentration of interleukin (IL)-3, IL-5, and IL-6 in
Mohammad Ghodsi, Vida Hojati, Armin Attaranzadeh, Bita Saifi   +3 more
doaj   +1 more source

The course and outcomes of COVID-19 in patients with ANCA-associated systemic vasculitis, receiving biological therapy (Rituximab, Mepolizumab): The results of the first 8 months of the pandemic

Научно-практическая ревматология, 2021
Objective. Currently, the issues of the effect of anti-B cell therapy or inhibitor of interleukin 5 on the risk of COVID-19 infecting and outcomes in patients with ANCA-associated vasculitis (AAV) has not been completely studied.
T. V. Beketova, V. V. Babak, M. D. Suprun   +2 more
doaj   +1 more source

The enigmatic eosinophil: investigation of the biological role of eosinophils in parasitic helmint infection

Memorias do Instituto Oswaldo Cruz, 1997
In many helminth infected hosts the number of eosinophils increases dramatically, often without any concurrent increases in the number of other leukocytes, so that eosinophils become the dominant cell type.
Karen S Ovington, Carolyn A Behm
doaj   +1 more source

Interleukin-4 and interleukin-5 as targets for the inhibition of eosinophilic inflammation and allergic airways hyperreactivity

Memorias do Instituto Oswaldo Cruz, 1997
Clinical and experimental investigations suggest that allergen-specific CD4+ T-cells, IgE and the cytokines IL-4 and IL-5 play central roles in initiating and sustaining an asthmatic response by regulating the recruitment and/or activation of airways ...
Paul S Foster, Simon P Hogan, Klaus I Matthaei, Ian G Young   +3 more
doaj   +1 more source

Optimization of Interleukin-5 Protein Expression in BL21 Strain of Escherichia Coli

مجله دانشکده پزشکی اصفهان, 2020
Background: In asthma, the relationship between number of eosinophils and severity of this disease supports the hypothesis that eosinophil is the major effector cell in inflammation of airway. Evolution of eosinophils is regulated by interlukin-5 (IL-5).
mina Jamalvandi, Hossein Khanahmad, Shiva Irani, Sayad Bastaminejad   +3 more
doaj   +1 more source

Cytokine profile associated with human chronic schistosomiasis mansoni

Memorias do Instituto Oswaldo Cruz, 2004
This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients.
Andréa Magalhães, Delfin Gonzalez Miranda, Roberval Gonzalez Miranda, Maria Ilma Araújo, Adriana Almeida de Jesus, Angela Silva, Luciana B Santana, Edward Pearce, Edgar M Carvalho, Amélia Ribeiro de Jesus   +9 more
doaj   +1 more source

Interleukin-5 modulates interleukin-8 secretion in eosinophilic inflammation

Mediators of Inflammation, 1998
Serum and BALF (bronchoalveolar lavage fluid) IL-8 levels and serum levels were investigated in Tox ocara canis infected guinea-pigs and the role of IL-5 as a modulator of cytokine secretion was studied.
L. H. Faccioli, A. I. Medeiros, A. Malheiro, R. C. L. R. Pietro, A. Januário, B. B. Vargaftig   +5 more
doaj   +1 more source