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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]
, 2012 BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.Thomas, GN, Willeit, P, Trip, MD, Willeit, J, Nelson, Christopher P, Samani, NJ, Danesh, J, Psaty, Bruce M., Assimes, Themistocles L., Stringham, Heather M, Kastelein, JJP, Adamovic, Svetlana, Franks, Paul W., Trip, Mieke D, Harris, Tamara B, Meade, TW, Thomas, Graham; id_orcid, Tivesten, A, de Bakker, PIW, Tybjærg-Hansen, Anne, Boehnke, M, de Bakker, Paul IW, Wilson, Anthony G, Trip, Mieke D., Witteman, Jacqueline C. M., Freitag, DF, Sarwar, Nadeem, Gao, P, Gallacher, John Edward, Ljunggren, Osten, Qi, Lu, Hall, Alistair S., Samani, Nilesh J., Karlsson, Magnus, Hofman, Bert, Goodall, AH, Watkins, H, Arbor, Ann, Davey Smith, George, Chambers, John C, Shaffer, Jonathan A, Butterworth, Adam S., Tracy, Russell P, O'Donnell, CJ, Gorman, Donal N., Psaty, Bruce M, Panagiotakos, DB, Wilde, Arthur AM, Best, LG, Di Angelantonio, Emanuele, Sundstrom, J, Butterworth, AS, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.), Cambien, Francois, Gregson, J, Gorman, Donal N, Best, Lyle G., Manson, JE, Rimm, Eric B, Wennberg, P, de Bakker, Paul I. W., Melzer, D, Qi, L, Gillum, Richard F, Kleber, ME, Gallacher, John, Kastelein, John JP, Chasman, DI, Cambien, F, Ridker, Paul M, Salomaa, Veikko, Hall, AS, Benjamin, Emelia J., Chasman, Daniel I, Salonen, JT, Kaptoge, S, Salonen, Jukka T., O'Donnell, Christopher J., Ingelsson, Erik, Benjamin, Emelia J, Freitag, Daniel F, Rader, Daniel J., Tracy, Russell P., Salonen, Jukka T, Saleheen, D, ?, ?, Salomaa, V, Clarke, Robert, Kleber, Marcus E., Chambers, JC, Witteman, Jacqueline C M, Braund, Peter S., Manson, JoAnn E., Boehnke, Michael, Ouwehand, Willem H, Rendon, A, Wilson, Anthony G., Harari, Olivier, Hopewell, Jemma C., Wilson, AG, Tracy, RP, Karlsson, M, Cantin, B, Reilly, Muredach P., Ohlsson, C, Melzer, David, IL6R Genetics Consortium Emerging Risk Factors Collaboration, Meade, Tom W, Benjamin, EJ, Stringham, Heather M., Freitag, Daniel F., Cantin, Bernard, Gregson, John, Chasman, Daniel I., Butterworth, Adam S, Reich, David, Braund, PS, Schunkert, H, Di Angelantonio, E, Ouwehand, WH, Harris, Tamara B., Thomas, G. Neil, Allin, Kristine H., Nelson, CP, Allin, Kristine Højgaard, Best, Lyle G, de Faire, Ulf, Davey-Smith, George, Kooner, Jaspal S, Gudnason, Vilmundur, Rimm, Eric B., Shaffer, Jonathan A., Sundstrom, Johan, Jansson, JO, Erdmann, Jeanette, Steri, M, Kauhanen, J, Holm, H, Samani, Nilesh J, Nordestgaard, BG, Mellstrom, Dan, Rader, Daniel J, Kaptoge, Stephen, Goodall, Alison H., Meade, Tom W., Clarke, R, Shaffer, JA, Ben-Shlomo, Yoav, Wilson, James F, Witteman, JCM, Ridker, PM, Davey-Smith, G, Tivesten, Asa, Koenig, W, Franks, Paul W.,, O'Donnell, Christopher J, Allin, Kristine H, van der Schoot, CE, Reilly, MP, Asselbergs, FW, Nelson, Christopher P., Hung, J, Danesh, John, Witteman, Jacqueline CM, Gudnason, V, Adamovic, S, Holm, Hilma, Kleber, Marcus E, Cushman, M, Ljunggren, Östen,, Erdmann, J, Koenig, Wolfgang, Rimm, EB, Hung, Joseph, Asselbergs, Folkert W., van der Schoot, C. Ellen, Wassertheil-Smoller, S, Kooner, Jaspal S., Panagiotakos, Demosthenes B, Franks, Paul, Willeit, Peter, Nordestgaard, Børge G, Kooner, JS, Chambers, John C., Tybjaerg-Hansen, Anne, Nordestgaard, Borge G., Tybjaerg-Hansen, A, Kauhanen, Jussi, Wilde, Arthur A. M., Gillum, RF, Watkins, Hugh, Mellstrom, D, Thomas, G Neil, Sarwar, N, de Faire, U, Wilde, AAM, Psaty, BM, Ben-Shlomo, Y, Panagiotakos, Demosthenes B., Ljunggren, O, Harris, TB, Sundström, Johan,, Reilly, Muredach P, Wilde, Arthur A M, Asselbergs, Folkert W, Woodward, Mark, Stringham, HM, Harari, O, Saleheen, Danish, Schunkert, Heribert, Hall, Alistair S, Cushman, Mary, Gorman, DN, Gillum, Richard F., Hopewell, Jemma C, Wilson, JF, IL6R Genetics Consortium, Rader, DJ, Wilson, James F., Kastelein, John J. P., Woodward, M, Hopewell, JC, Hofman, Albert, Rendon, Augusto, Wennberg, Patrik, Jansson, John-Olov, Wilhelmsen, L, Reich, D, Manson, JoAnn E, Onat, A, Amouyel, Philippe, Hamsten, A, Ingelsson, E, Franks, Paul W, Willeit, Johann, Onat, Altan, Wilhelmsen, Lars, Assimes, Themistocles L, Gallacher, J, Wassertheil-Smoller, Sylvia, van der Schoot, C Ellen, Assimes, TL, Goodall, Alison H, Franks, PW, Amouyel, P, Steri, Maristella, Ohlsson, Claes, Braund, Peter S, Allin, KH, Hamsten, Anders, Ridker, Paul M., Ouwehand, Willem H., Gao, Pei, Uitterlinden AG, Stark K, Asselbergs FW, Gregson J, Baumert J, Böhm BO, Kleber ME, Butterworth AS, de Jong JS, Yarnell JW, Danesh J. Collaborators Assimes TL, Wennberg P, Rimm EB, Preuss M, Qi L, Ripatti S, Stefanadis C, Smith AV, Ben Shlomo Y, Rasheed A, Ridker PM, Goodall AH, Karlsson, Magnus,, Kuusisto J, Tikkanen E, Rose LM, Perola M, Dupuis J, Armitage J, Mukamal KJ, Wilson JF, Nordestgaard BG, Hu FB, Jula A, Cheng KK, Reich D, Thorsteinsdóttir U, Thompson PL, Quertermous T, Nieminen MS, Illig T, Lind L, Gallacher J, Tivesten Å, Basu S, Mellström D, Stringham HM, Winkelmann BR, Silveira A, Tivesten, Åsa,, O'Donnell CJ, Whincup PH, Arveiler D, Morris RW, Guralnik JM, Sinisalo J, Maiwald S, Scharnagl H, Jansson JH, van der Schouw YT, Jansson JO, Tuomainen TP, Chasman DI, Freitag DF, Hengstenberg C, Tracy RP, Peden JF, Dehghan A, Fontes JD, Lam TH, Gigante B, Sivapalaratnam S, Hall AS, Harris TB, Lund University., Laakso M, Wilde AA, Nahrstaedt J, Deloukas P, Dagenais GR, Sarwar N, Qu L, Hofman A, Benjamin EJ, Loley C, Kastelein JJ, Rumley A, Heckbert SR, Koenig IR, Beilby JP, Clarke R, Bezzina CR, Amouyel P, Howard BV, Kaptoge S, de Bakker PI, Willenborg C, Shungin D, Schunkert H, Wassertheil Smoller S, Gillum RF, Barroso I, Mellström, Dan,, Gao P, Di Angelantonio E, Tuomilehto J, Cantin B, Shaffer JA, Jansson, John-Olov,, Ingelsson E, Männistö S, Knowles JW, Wilhelmsen L, Singleton AB, Koenig W, Chambers JC, Das D, Davidson KW, Psaty BM, Willeit J, Willeit P, Hlatky MA, Hankinson SE, Schreiber S, Wiggins KL, Panagiotakos DB, Dekker LR, Salonen JT, Manson JE, Thomas GN, Watkins H, Lokki ML, Pai J, Ljunggren Ö, McQuillan BM, Buring J., Adamovic, Svetlana,, Go AS, Gorman DN, Boehnke M, Bis JC, Witteman JC, Adamovic S, Sheikh N, Havulinna AS, Thorleifsson G, Reilly MP, Folsom AR, Sanna S, Fraser R, Meisinger C, Karlsson MK, Kauhanen J, Li M, van Duijn CM, Cambien F, Samani NJ, Davey Smith G, Assimes TL, de Faire U, Meade TW, van der Schoot CE, Verschuren WM, Ohlsson, Claes,, Motazacker M, Allin KH, Sabater Lleal M, Smith NL, Danesh J, Jackson A, Kurl S, Tanck M, Shea SJ, Yin X, Kooner JS, Collins R, Zhang W, Steri M, Thorand B, Saleheen D, CUCCA, Francesco, Gudnason V, Harari O, Melzer D, Onat A, Best LG, Tybjærg Hansen A, Nelson CP, Onland Moret NC, Franks PW, Rosengren A, Karlsson M, Erdmann J, Basart H, Wannamethee SG, Salomaa V, Ouwehand WH, Trip MD, Woodward M, Rendon A, Parish S, Balmforth AJ, Braund PS, Stefansson K, Abecasis GR, Ohlsson C, Sundström J, Hveem K, Hólm H, Ferrucci L, Syvänen AC, Hallmans G, Hopewell JC, Lowe G, Pitsavos C, Kiechl S, Farrall M, Thorgeirsson G, Hamsten A, Rader DJ, Boer JM, Franks, Paul,, Jiang CC, Chrysohoou C, Hung J, Bandinelli S, Schlessinger D, März W, Uda M, Cushman M, Wilson AG, Thompson JR, Qasim A, Sarwar, N;Butterworth, AS;Freitag, DF;Gregson, J;Willeit, P;Gorman, DN;Gao, P;Saleheen, D;Rendon, A;Nelson, CP;Braund, PS;Hall, AS;Chasman, DI;Tybjærg-Hansen, A;Chambers, JC;Benjamin, EJ;Franks, PW;Clarke, R;Wilde, AA;Trip, MD;Steri, M;Witteman, JC;Qi, L;van der Schoot, CE;de Faire, U;Erdmann, J;Stringham, HM;Koenig, W;Rader, DJ;Melzer, D;Reich, D;Psaty, BM;Kleber, ME;Panagiotakos, DB;Willeit, J;Wennberg, P;Woodward, M;Adamovic, S;Rimm, EB;Meade, TW;Gillum, RF;Shaffer, JA;Hofman, A;Onat, A;Sundström, J;Wassertheil-Smoller, S;Mellström, D;Gallacher, J;Cushman, M;Tracy, RP;Kauhanen, J;Karlsson, M;Salonen, JT;Wilhelmsen, L;Amouyel, P;Cantin, B;Best, LG;Ben-Shlomo, Y;Manson, JE;Davey-Smith, G;de Bakker, PI;O'Donnell, CJ;Wilson, JF;Wilson, AG;Assimes, TL;Jansson, JO;Ohlsson, C;Tivesten, Å;Ljunggren, Ö;Reilly, MP;Hamsten, A;Ingelsson, E;Cambien, F;Hung, J;Thomas, GN;Boehnke, M;Schunkert, H;Asselbergs, FW;Kastelein, JJ;Gudnason, V;Salomaa, V;Harris, TB;Kooner, JS;Allin, KH;Nordestgaard, BG;Hopewell, JC;Goodall, AH;R, Campbell H, Wild S, Kooner AS +489 morecore +5 more sourcesPulmonary biology of anti-interleukin 5 antibodies
Memorias do Instituto Oswaldo Cruz, 1997 Interleukin 5 (IL-5) is a critical cytokine for the maturation of eosinophil precursors to eosinophils in the bone marrow and those eosinophils then accumulate in the lungs during asthma. We have studied anti IL-5 antibodies on allergic responses in mice,RW Egan, D Athwahl, C-C Chou, RW Chapman, S Emtage, C-H Jenh, TT Kung, PJ Mauser, NJ Murgolo, MW Bodmer +9 moredoaj +2 more sources
