Results 41 to 50 of about 673,896 (307)

Heterogeneity of Group 2 Innate Lymphoid Cells Defines Their Pleiotropic Roles in Cancer, Obesity, and Cardiovascular Diseases

Frontiers in Immunology, 2022
Group 2 innate lymphoid cells (ILC2s) are typically known for their ability to respond rapidly to parasitic infections and play a pivotal role in the development of certain allergic disorders.
Masashi Ikutani, Susumu Nakae, Susumu Nakae   +2 more
doaj   +1 more source

Immune Responses in Human Necatoriasis: Association between Interleukin-5 Responses and Resistance to Reinfection [PDF]

, 2004
Cytokine and proliferative responses to Necator americanus infection were measured in a treatment-reinfection study of infected subjects from an area of Papua New Guinea where N. americanus is highly endemic.
Brown, A.P., Pritchard, D.I., Quinnell, R.J., Raiko, A., Shaw, M.-A.   +4 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Anti-Interleukin-5-Therapie bei eosinophilen Erkrankungen [PDF]

, 2018
Zusammenfassung: Bei einer Reihe von Erkrankungen, die durch eine Eosinophilie charakterisiert sind, findet man erhöhte Spiegel von Interleukin- (IL-)5 im Blut und/oder Gewebe.
Braathen, L.R., Simon, D., Simon, H.-U
core  

Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]

, 2012
Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Nandra, KK, Patel, NSA, Thiemermann, C
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Uncovering how interleukin-5 and interleukin-23 shape human immune defense against Salmonella enterica Typhi

Journal of Microbiology and Infectious Diseases
Background: Salmonella enterica serotype Typhi remains a major global health concern, particularly in regions with limited resources. Interleukins such as interleukin-5 and interleukin-23 are thought to play pivotal roles in shaping the host's ...
Ruaa Kareem Surhan, Aqeel A. Al-Sadawi, Ali Reyadh Medhat, Ahmed Al Obaidi   +3 more
doaj   +1 more source

Eosinophil Activation Status in Separate Compartments and Association with Asthma

Frontiers in Medicine, 2017
Asthma is frequently characterized by eosinophil-rich airway inflammation. Airway eosinophilia is associated with asthma exacerbations and likely plays a part in airway remodeling.
Mats W. Johansson
doaj   +1 more source

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]

, 1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB, Erle, DJ, Folkesson, HG, Locksley, RM, Matthay, MA, Warnock, ML, Wiener-Kronish, JP   +6 more
core  

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Allen, Judith E, Graham, Andrea L, Lamb, Tracey J, Read, Andrew F   +3 more
core   +3 more sources