Results 41 to 50 of about 12,528,653 (292)
The effects of anti-interleukin-5 on SABA rescue use.
, 2016 The effects of anti-interleukin-5 on SABA rescue use.
Ting Liu (45625) +4 more
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[Anti-interleukin-5 therapy for eosinophilic diseases] [PDF]
, 2007 In a number of diseases with eosinophilia, elevated interleukin (IL)-5 levels are detected in the peripheral blood and/or tissues. IL-5 plays an important role in regulating the production, differentiation, recruitment, activation, and survival of ...
Simon, H-U, Simon, D, Braathen, L R
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Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease
Respiratory Research, 2001 Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 ...
Chapman Richard W +4 more
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Drugs in Context, 2019 Background: Asthma is an inflammatory disease of the airways with symptoms that vary over time and intensity, sometimes leading to disability or even death. Eosinophilic asthma accounts for 25% of cases of severe asthma.
Olalla Montero-Pérez +2 more
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Selective suppression of leukocyte recruitment in allergic inflammation
Memorias do Instituto Oswaldo Cruz, 2005 Allergic diseases result in a considerable socioeconomic burden. The incidence of allergic diseases, notably allergic asthma, has risen to high levels for reasons that are not entirely understood.
CL Weller, PJ Jose, TJ Williams
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Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
, 2003 Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda +10 more
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Interleukin 5 as a therapeutic target in severe asthma
Alergologia PolskaAsthma is a chronic inflammatory disease of the airways, the severe forms of which can lead to severe exacerbations and significant deterioration in quality of life.
Hubert Bajer, Rafał Pawliczak
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Covalent modification of the interleukin‐5 receptor by isothiazolones leads to inhibition of the binding of interleukin‐5 [PDF]
European Journal of Biochemistry, 1994 Using a fusion protein of the human interleukin‐5‐receptor α chain (hILSRα) and the human IgG Cγ3 chain (hIL5Rα‐hγ3), we have developed a solid‐phase assay for high‐flux screening of a collection of synthetic compounds. We report on the identification of isothiazolone derivatives as potent inhibitors of binding of interleukin‐5 (IL5) to the hIL5Ra, as ...
R, Devos +7 more
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Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
, 2016 Begg’s funnel plot evaluated the effect of anti-interleukin-5 on FEV1.
Ting Liu (45625) +4 more
core +1 more source
The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
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