Results 21 to 30 of about 673,896 (307)

Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia

Frontiers in Immunology, 2020
Background: Eosinophils develop from CD34+ progenitor cells in the bone marrow under the influence of interleukin (IL)-5. Several cell types produce IL-5, including type 2 innate lymphoid cells (ILC2s).
Emma Boberg, Kristina Johansson, Carina Malmhäll, Jenny Calvén, Julie Weidner, Madeleine Rådinger   +5 more
doaj   +1 more source

Episodic angioedema associated with eosinophilia [PDF]

Anais Brasileiros de Dermatologia, 2017
: We report a 12-year-old girl who presented with recurrent angioedema on the face, trunk, and extremities, and concomitant marked weight gain for 5 years.
Fang Liu, Wenxing Hu, Haibo Liu, Min Zhang, Hong Sang   +4 more
doaj   +1 more source

Impaired interferon-γ responses, increased interleukin-17 expression, and a tumor necrosis factor–α transcriptional program in invasive aspergillosis [PDF]

, 2009
This article is available open access through the publisher’s website. Copyright @ 2009 Oxford University Press.Background - Invasive aspergillosis (IA) is the most common cause of death associated with fungal infection in the developed world ...
Armstrong-James, DP, Bignell, E, Haynes, K, Rogers, NJ, Rogers, TRF, Stark, J, Teo, I, Turnbull, SA   +7 more
core   +1 more source

Mepolizumab in the treatment of bronchial asthma in children

Медицинский совет, 2020
Severe bronchial asthma in children remains a serious problem, which is due to the high risk of mortality, side effects of therapy with high doses of glucocorticosteroids, significant consumption of health resources.
Yu. L. Mizernitskiy, I. M. Mel'nikova, V. A. Pavlenko   +2 more
doaj   +1 more source

Interleukin-5 Mediates Parasite-Induced Protection against Experimental Autoimmune Encephalomyelitis: Association with Induction of Antigen-Specific CD4+CD25+ T Regulatory Cells

Frontiers in Immunology, 2017
ObjectiveTo examine if the protective effect of parasite infection on experimental autoimmune encephalomyelitis (EAE) was due to interleukin (IL)-5, a cytokine produced by a type-2 response that induces eosinophilia.
Giang T. Tran, Paul L. Wilcox, Lindsay A. Dent, Catherine M. Robinson, Nicole Carter, Nirupama D. Verma, Bruce M. Hall, Suzanne J. Hodgkinson   +7 more
doaj   +1 more source

Expression level of micro-RNA-1, IL-5, IFNγ, and TNFα in adult-onset asthmatic patients

Egyptian Journal of Chest Disease and Tuberculosis, 2021
Background and objective Asthma is an inflammatory process, where T lymphocytes cells, mainly the Th1/Th2 cells, participate in bronchial asthma’s pathogenesis and progression.
Shaimaa M Abo-Youssef, Amira H Allam, Mysa S Mustafa, Hasnaa S Abd el Hamid, Amany K Shahat, Hany H Moussa   +5 more
doaj   +1 more source

Eosinophil Apoptosis and Clearance in Asthma [PDF]

, 2013
Peer reviewedPublisher ...
Bickham U.R., Duval E., Fadok V.A., Fadok V.A., Gaipl U.S., Hart S.P., Luttmann W., Meagher L.C., Schwartz B.R., Walsh G.M.   +9 more
core   +3 more sources

Interleukin 5 as a therapeutic target in severe asthma

Alergologia Polska
Asthma is a chronic inflammatory disease of the airways, the severe forms of which can lead to severe exacerbations and significant deterioration in quality of life.
Hubert Bajer, Rafał Pawliczak
doaj   +1 more source

Short-term stimulation with interleukin (IL)-4 enhances purified protein derivative-induced production of an eosinophil chemotactic lymphokine, but suppresses IL-5 production

Allergology International, 1998
The effect of interleukin (IL)-4 on eosinophil chemotactic lymphokine (ECL) production from peripheral blood mononuclear cells (PBMC) stimulated with purified protein derivative (PPD) was examined.
Takehiko Nishiyama, Taishi Hata, Hiroki Okada, Mitsuomi Hiroshima   +3 more
doaj   +1 more source

Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population [PDF]

, 2017
Acknowledgments The authors thank Derek Skinner (Cambridge Research Support Ltd, Oakington, Cambridge, UK) for assistance with data extraction.Peer reviewedPublisher ...
Gibson, Danny, Golam, Sarowar, Hillyer, Elizabeth V, Kerkhof, Marjan, Price, David B, Soriano, Joan B, Tran, Trung N   +6 more
core   +1 more source