Results 21 to 30 of about 12,528,653 (292)

Interleukin-5 and Interleukin-5 Receptor Polymorphism in Asthma

, 2023
Asthma is a common chronic inflammatory disease of the airways of the lungs, in the world. It’s associated with type 2 cytokines interleukin-4, IL-5, and IL-13, which promote airway eosinophilia, bronchial hyperresponsiveness, mucus overproduction, and immunogloubulin E synthesis.
Raghdah Maytham Hameed, Haidar Abdul Amir Najim Abood, Mohanad Mohsin Ahmed   +2 more
openaire   +1 more source

The enigmatic eosinophil: investigation of the biological role of eosinophils in parasitic helmint infection

Memorias do Instituto Oswaldo Cruz, 1997
In many helminth infected hosts the number of eosinophils increases dramatically, often without any concurrent increases in the number of other leukocytes, so that eosinophils become the dominant cell type.
Karen S Ovington, Carolyn A Behm
doaj   +1 more source

Optimization of Interleukin-5 Protein Expression in BL21 Strain of Escherichia Coli

مجله دانشکده پزشکی اصفهان, 2020
Background: In asthma, the relationship between number of eosinophils and severity of this disease supports the hypothesis that eosinophil is the major effector cell in inflammation of airway. Evolution of eosinophils is regulated by interlukin-5 (IL-5).
mina Jamalvandi, Hossein Khanahmad, Shiva Irani, Sayad Bastaminejad   +3 more
doaj   +1 more source

Interleukin-4 and interleukin-5 as targets for the inhibition of eosinophilic inflammation and allergic airways hyperreactivity

Memorias do Instituto Oswaldo Cruz, 1997
Clinical and experimental investigations suggest that allergen-specific CD4+ T-cells, IgE and the cytokines IL-4 and IL-5 play central roles in initiating and sustaining an asthmatic response by regulating the recruitment and/or activation of airways ...
Paul S Foster, Simon P Hogan, Klaus I Matthaei, Ian G Young   +3 more
doaj   +1 more source

The role of interleukin 5 in asthma [PDF]

Expert Review of Clinical Immunology, 2016
Eosinophils were first named in 1879 by Paul Ehrlich, who described their capacity to be stained by eosin, a bright red synthetic dye [1].
Varricchi, Gilda, Canonica, Giorgio W.
openaire   +4 more sources

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B., Robertson, S.E., Gracie, J.A.   +2 more
core   +1 more source

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +1 more source

A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes [PDF]

, 2016
Air pollutants have been linked to type 2 diabetes (T2D), hypothesized to act through inflammatory pathways and may induce interleukin-6 gene (IL6) in the airway epithelium. The cytokine interleukin-6 may impact on glucose homeostasis.
Imboden, Medea, Eze, Ikenna C, von Eckardstein, Arnold, Margaret W. Gerbase, Turk, Alexander, Ikenna C. Eze, Christian Schindler, Eze, Ikenna C., Kumar, Ashish, Probst-Hensch, Nicole, Daiana Stolz, Kronenberg, Florian, Medea Imboden, Adam, Martin, Künzli, Nino, Alexander Turk, Stolz, Daiana, Gerbase, Margaret W, Martin Adam, Nino Künzli, Gerbase, Margaret W., Florian Kronenberg, Nicole Probst-Hensch, Schindler, Christian, Arnold von Eckardstein, Ashish Kumar   +25 more
core   +1 more source

cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]

, 2000
By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Baeuerle, Patrick A., Kaspers, Bernd, Kirsten Schneider, Schneider, Kirsten, Baeuerle, Daniela, Daniela Baeuerle, Kirsten C. Weining, Puehler, Florian, Elvers, Sandra, Weining, Kirsten C., Florian Puehler, Sandra Elvers, Bernd Kaspers   +15 more
core   +1 more source

Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia

Frontiers in Immunology, 2020
Background: Eosinophils develop from CD34+ progenitor cells in the bone marrow under the influence of interleukin (IL)-5. Several cell types produce IL-5, including type 2 innate lymphoid cells (ILC2s).
Emma Boberg, Kristina Johansson, Carina Malmhäll, Jenny Calvén, Julie Weidner, Madeleine Rådinger   +5 more
doaj   +1 more source