Results 41 to 50 of about 1,081,549 (346)

Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies. [PDF]

, 2015
Treatment of hematological malignant disorders has been improved over the last years, but high relapse rate mainly attributable to the presence of minimal residual disease still persists.
Biassoni, Biron, Björklund, Brodin, Bryceson, Burns, Campbell, Cooley, Cooper, Cooper, Curti, Davies, Di Santo, Di Santo, Farag, Fehniger, Fogler, Foley, Freud, Gasser, Gilfillan, Grimm, Guethlein, Herberman, Huntington, Joncker, Kiessling, Killig, King, Kröger, Lajoie, Lanier, Leong, Ljunggren, Lowe, Lundqvist, Mancusi, McQueen, Miller, Moretta, Moretta, Moretta, Nguyen, Oevermann, Ouyang, Perussia, Phillips, Romagnani, Romee, Rosenberg, Rosenberg, Rosenberg, Ruggeri, Santoni, Stabile, Stabile, Stern, Stringaris, Thielens, Torelli, Trinchieri, Trinchieri, Vago, Valés-Gómez, Venstrom, Vivier, Whitelaw, Zorn   +67 more
core   +1 more source

Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy [PDF]

, 2020
Microglia, the major endogenous immune cells of the central nervous system, mediate critical degenerative and regenerative responses in ischaemic stroke.
Chen, Ruoli, Dallas, Mark L., Jenkins, Stuart, Rawlinson, Charlotte, Thei, Laura   +4 more
core   +3 more sources

Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model. [PDF]

PLoS ONE, 2016
The need for new options for chronic lung diseases promotes the research on stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can modulate lung inflammation, but the data on cellular processes involved in early airway ...
Konrad Urbanek, Antonella De Angelis, Giuseppe Spaziano, Elena Piegari, Maria Matteis, Donato Cappetta, Grazia Esposito, Rosa Russo, Gioia Tartaglione, Raffaele De Palma, Francesco Rossi, Bruno D'Agostino   +11 more
doaj   +1 more source

Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2) [PDF]

, 2017
Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of con-firmed HF cases in the United States. However, there are no highly effective evidence-basedtreatments currently available for these patients.
Abbate, Antonio, Abouzaki, Nayef, Arena, Ross, Biondi-zoccai, Giuseppe, Buckley, Leo F., Canada, Justin M., Carbone, Salvatore, Dixon, Dave L., Oddi-erdle, Claudia, Trankle, Cory R., Van Tassell, Benjamin W.   +10 more
core   +1 more source

Monoclonal antibodies reactive with the mouse interleukin 5 receptor. [PDF]

The Journal of experimental medicine, 1989
The rat mAbs R52.120 and R52.625 inhibit the action of IL-5 on both IL-5-sensitive cell lines and freshly isolated splenic B lymphocytes. Neither antibody inhibits the proliferative cell responses promoted by IL-2, IL-3, or IL-4. Purified R52.120+ lymphoid spleen cells contain 15-20-fold higher numbers of B lymphocytes responding to IL-5 in the form of
A G, Rolink, F, Melchers, R, Palacios
openaire   +2 more sources

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. [PDF]

, 2016
Natural killer (NK) cells are functionally suppressed in the glioblastoma multiforme (GBM) tumor microenvironment. We have recently shown that survival and differentiation of cancer stem-like cells (CSCs)/poorly differentiated tumors are controlled ...
Bui, Vickie T, Cacalano, Nicholas, Inagaki, Akihito, Jewett, Anahid, Kasahara, Noriyuki, Kaur, Kawaljit, Kozlowska, Anna K, Topchyan, Paytsar, Tseng, Han-Ching   +8 more
core   +1 more source

Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model

Molecular Pain, 2020
Background Chronic pain is frequently comorbid with anxiety disorder, thereby complicating its treatment. Polydatin, a component from the root of Polygonum cuspidatum , has shown neuroprotection in the central nervous system. However, its effects on pain
Shao-Yu Guan, Kun Zhang, Xin-Shang Wang, Le Yang, Bin Feng, Dan-Dan Tian, Mei-Rong Gao, Shui-Bing Liu, An Liu, Ming-Gao Zhao   +9 more
doaj   +1 more source

Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production

Journal of Experimental Medicine, 1991
Interleukin 5 (IL-5) has been suggested to be involved in the growth and differentiation of B cells and eosinophils. Especially, Ly-1+ B cells, which have been considered to produce autoantibodies, are selectively developed by this lymphokine in long ...
A. Tominaga, S. Takaki, N. Koyama, S. Katoh, R. Matsumoto, M. Migita, Y. Hitoshi, Yukio Hosoya, Shigehito Yamauchij Yoshiyuki Kanai, J. Miyazaki, G. Usuku, Ken-ichi Yamamura, K. Takatsu   +12 more
semanticscholar   +1 more source

Expression of interleukin 2 receptors on activated human B cells. [PDF]

, 1984
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF, Depper, JM, Goldman, CK, Greene, WC, Korsmeyer, SJ, Leonard, WJ, Robb, RJ, Sharrow, SO, Waldmann, TA   +8 more
core  

Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. [PDF]

, 2019
Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming.
Canter, Robert J, Gingrich, Alicia A, Modiano, Jaime F   +2 more
core   +2 more sources